Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Simon Burgener"'
Autor:
Charles AR Cotton, Iria Bernhardsgrütter, Hai He, Simon Burgener, Luca Schulz, Nicole Paczia, Beau Dronsella, Alexander Erban, Stepan Toman, Marian Dempfle, Alberto De Maria, Joachim Kopka, Steffen N Lindner, Tobias J Erb, Arren Bar-Even
Publikováno v:
eLife, Vol 9 (2020)
The promiscuous activities of enzymes provide fertile ground for the evolution of new metabolic pathways. Here, we systematically explore the ability of E. coli to harness underground metabolism to compensate for the deletion of an essential biosynth
Externí odkaz:
https://doaj.org/article/235537e1aaab4346aaee0e7963eb12d8
Publikováno v:
Molecules, Vol 23, Iss 1, p 68 (2017)
Although flavoenzymes have been studied in detail, the molecular basis of their dioxygen reactivity is only partially understood. The members of the flavin adenosine dinucleotide (FAD)-dependent acyl-CoA dehydrogenase and acyl-CoA oxidase families ca
Externí odkaz:
https://doaj.org/article/1b1de3ba4f104ac9941c402669e477bd
Autor:
Simon Burgener, Thomas R. Ward
Publikováno v:
Chem Catalysis. 2:2427-2429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cbfe6219190661b1f338f8f2d8e9791
https://doi.org/10.1016/j.checat.2022.09.031
https://doi.org/10.1016/j.checat.2022.09.031
Design of experiments (DoE) plays an important role in optimizing the catalytic performance of chemical reactions. The most commonly-used DoE relies on the response surface methodology (RSM) to model the variable space of experimental condi-tions wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3cdf0d5c5143e2b5c869e4173b1b7d
https://doi.org/10.26434/chemrxiv-2023-q8484
https://doi.org/10.26434/chemrxiv-2023-q8484
Publikováno v:
Nature Catalysis. 3:186-192
Modern-day chemical synthesis is still mainly a linear process that focuses on the design and optimization of single catalysts and reactions. By contrast, (bio)synthesis in nature is carried out by metabolic networks that are highly integrated, self-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9ca9375ea4591b2e9b769e958efd9e
https://doi.org/10.1038/s41929-020-0429-x
https://doi.org/10.1038/s41929-020-0429-x
Publikováno v:
Angewandte Chemie (International Ed. in English)
The synthesis of complex molecules from simple, renewable carbon units is the goal of a sustainable economy. Here we explored the biocatalytic potential of the thiamine‐diphosphate‐dependent (ThDP) oxalyl‐CoA decarboxylase (OXC)/2‐hydroxyacyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe80165602914834c505f3530eacbab
https://doi.org/10.1002/anie.201915155
https://doi.org/10.1002/anie.201915155
Publikováno v:
Angewandte Chemie. 132:5569-5573
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4adcf57a988c8bfb321a8d167b37ee4e
https://doi.org/10.1002/ange.201915155
https://doi.org/10.1002/ange.201915155
Publikováno v:
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering ISBN: 9780124095472
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c6b29647456b93e20371d7f0db6191
https://doi.org/10.1016/b978-0-32-390644-9.00082-2
https://doi.org/10.1016/b978-0-32-390644-9.00082-2
Publikováno v:
Current Opinion in Biotechnology
Current Opinion in Biotechnology 60 (2019)
Current Opinion in Biotechnology, 60, 221-229
Curr Opin Biotechnol
Current Opinion in Biotechnology 60 (2019)
Current Opinion in Biotechnology, 60, 221-229
Curr Opin Biotechnol
Conversion of biological feedstocks into value-added chemicals is mostly performed via microbial fermentation. An emerging alternative approach is the use of cell-free systems, consisting of purified enzymes and cofactors. Unfortunately, the in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86952745a4deb96b2110e38485f45c77
https://doi.org/10.1016/j.copbio.2019.05.003
https://doi.org/10.1016/j.copbio.2019.05.003
Autor:
Alberto De Maria, Marian Dempfle, Joachim Kopka, Charles A. R. Cotton, Nicole Paczia, Iria Bernhardsgrütter, Arren Bar-Even, Tobias J. Erb, Beau Dronsella, Steffen N. Lindner, Luca Schulz, Stepan Toman, Hai He, Alexander Erban, Simon Burgener
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The promiscuous activities of enzymes provide fertile ground for the evolution of new metabolic pathways. Here, we systematically explore the ability ofE. colito harness underground metabolism to compensate for the deletion of an essential biosynthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc41bbbbfba4e20bf99765b9aa6013c
https://hdl.handle.net/21.11116/0000-0007-0058-6
https://hdl.handle.net/21.11116/0000-0007-0058-6