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pro vyhledávání: '"Simon Bendsen"'
Autor:
Simon Bendsen, Marie Brinch, A. Kathleen McClendon, Jennifer S. Dickey, Amanda C. Gentry, Anni H. Andersen, Neil Osheroff
Publikováno v:
McClendon, A, Gentry, A, Dickey, J, Brinch, M, Bendsen, S P, Andersen, A H & Osheroff, N 2008, ' Bimodal Recognition of DNA Geometry by Human Topoisomerase IIα: Preferential Relaxation of Positively Supercoiled DNA Requires Elements in the C-terminal Domain ', Biochemistry, vol. 47, pp. 13169-78 .
Human topoisomerase IIalpha, but not topoisomerase IIbeta, can sense the geometry of DNA during relaxation and removes positive supercoils10-fold faster than it does negative superhelical twists. In contrast, both isoforms maintain lower levels of DN
Autor:
Anni H. Andersen, Simon Bendsen, Sissel Juul, Birgitta R. Knudsen, Jørn Koch, Hanne Laerke Jørgensen, Felicie F. Andersen, Magnus Stougaard, Kristoffer Hald
Publikováno v:
Aarhus University
Andersen, F F, Stougaard, M, Jørgensen, H L, Bendsen, S P, Jensen, S J, Hald, K, Andersen, A H, Koch, J E & Knudsen, B R 2009, ' Multiplexed Detection of Site Specific Recombinase and DNA Topoisomerase Activities at the Single Molecule Level ', A C S Nano, vol. 3, no. 12 .
Andersen, F F, Stougaard, M, Jørgensen, H L, Bendsen, S P, Jensen, S J, Hald, K, Andersen, A H, Koch, J E & Knudsen, B R 2009, ' Multiplexed Detection of Site Specific Recombinase and DNA Topoisomerase Activities at the Single Molecule Level ', A C S Nano, vol. 3, no. 12 .
We previously demonstrated the conversion of a single human topoisomerase I mediated DNA cleavage-ligation event happening within nanometer dimensions to a micrometer-sized DNA molecule, readily detectable using standard fluorescence microscopy. This
Autor:
Anni H. Andersen, Marie Brinch, Camilla Skouboe, Simon Bendsen, Vibe H. Oestergaard, Birgitta R. Knudsen
Publikováno v:
Biochemistry. 48(27)
We have characterized a human topoisomerase IIalpha enzyme with a deletion of the conserved QTK loop, which extends from the transducer domain to the ATP-binding pocket in the GHKL domain. The loop has been suggested to play a role for interdomain co
Autor:
Kamilla Mundbjerg, Jakob Madsen Pedersen, Simon Bendsen, Lotte Andreasen, Birgitta Ruth Knudsen, Lotte Bjergbaek, Anni Andersen
Publikováno v:
Aarhus University
Mundbjerg, K, Pedersen, J M, Bendsen, S, Andreasen, L, Knudsen, B R, Bjergbaek, L & Andersen, A H 2008, ' DNA topoisomerases-Cellular tools with huge impact on genome stability ', Kos, Greece, 17/10/2008-22/10/2008, .
Mundbjerg, K, Pedersen, J M, Bendsen, S, Andreasen, L, Knudsen, B R, Bjergbaek, L & Andersen, A H 2008, ' DNA topoisomerases-Cellular tools with huge impact on genome stability ', Kos, Greece, 17/10/2008-22/10/2008, .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::37fd1d7c2af7e55a27541ce9860c9b0b
https://pure.au.dk/portal/en/publications/dna-topoisomerases--cellular-tools-with-huge-impact-on-genome-stability(3fe9eb70-1561-11df-b95d-000ea68e967b).html
https://pure.au.dk/portal/en/publications/dna-topoisomerases--cellular-tools-with-huge-impact-on-genome-stability(3fe9eb70-1561-11df-b95d-000ea68e967b).html