Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Simon B. Lang"'
Autor:
Wayland E. Noland, Neil J. Kroll, Matthew P. Huisenga, Ruixian A. Yue, Simon B. Lang, Nathan D. Klein, Kenneth J. Tritch
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 12, Pp 550-554 (2014)
The title tetrone compound, C32H22N2O4S· 0.5C8H10, is the major product (50% yield) of an attempted Diels–Alder reaction of 2-(α-styryl)thiophene with N-phenylmaleimide (2 equivalents) in toluene. Recrystallization of the resulting powder from p-
Externí odkaz:
https://doaj.org/article/91ffe30add3546529f29c4f8db566a56
Autor:
Shuilian Zhao, Takao Suzuki, Tingting Yu, Simon B. Lang, Zhiqi Qi, Jianming Bao, Rohan R Merchant
Publikováno v:
Organic Letters. 22:4180-4184
In this letter, we report a general one-pot strategy that utilizes three elementary steps (decarboxylative hydrazination, Boc deprotection, and heterocycle condensation) to regioselectively prepare hindered C(sp3) substituted pyrazoles and triazoles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8c7d439993e3dc5577c686cbb3db6b2
https://doi.org/10.1021/acs.orglett.0c01254
https://doi.org/10.1021/acs.orglett.0c01254
Autor:
Rohan R, Merchant, Simon B, Lang, Tingting, Yu, Shuilian, Zhao, Zhiqi, Qi, Takao, Suzuki, Jianming, Bao
Publikováno v:
Organic letters. 22(11)
In this letter, we report a general one-pot strategy that utilizes three elementary steps (decarboxylative hydrazination, Boc deprotection, and heterocycle condensation) to regioselectively prepare hindered C(sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb4b3e0c311de5de3f27c306f1628aab
https://pubmed.ncbi.nlm.nih.gov/32383385
https://pubmed.ncbi.nlm.nih.gov/32383385
Autor:
Diane T. Vo, Kenny Xiong, John A. Rosenow, Nathan D. Klein, Steven P. Daniels, Jidapa Ratanayanon, Ruixian A. Yue, Neil J. Kroll, Wayland E. Noland, Matthew P. Huisenga, Hoyeon Kim, Nathan S. Duncan, Jacob K. Riley, Benjamin Johnson, Ryan J. Herzig, Kenneth J. Tritch, Andrei Nesmelov, Bee K. Ong, Simon B. Lang
Publikováno v:
Journal of Heterocyclic Chemistry. 55:2698-2714
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59fe0644996e6a89931355a792194c12
https://doi.org/10.1002/jhet.3327
https://doi.org/10.1002/jhet.3327
Publikováno v:
Chemical Science. 9:3215-3220
Two synergistic approaches to the facile assembly of complex α-trifluoromethyl alkenes are described. Using α-trifluoromethyl-β-silyl alcohols as masked trifluoromethyl alkenes, cross-coupling or related functionalization processes at distal elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1048779499e6220464c1007c85943953
https://doi.org/10.1039/c7sc05420c
https://doi.org/10.1039/c7sc05420c
Autor:
Gary A. Molander, Osvaldo Gutierrez, Ryan Dykstra, María Jesús Cabrera-Afonso, Simon B. Lang, Christopher B. Kelly, Zhi-Peng Lu
Publikováno v:
Chemical Science. 9:3186-3191
This report details the development and implementation of a strategy to construct aryl- and heteroaryl sulfones via Ni/photoredox dual catalysis. Using aryl sulfinate salts, the C–S bond can be forged at room temperature under base-free conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a27dbcc0a5014fd1c7f991fcf6fb2ce
https://doi.org/10.1039/c7sc05402e
https://doi.org/10.1039/c7sc05402e
Publikováno v:
Angewandte Chemie International Edition. 56:15073-15077
Described is a facile, scalable route to access functional-group-rich gem-difluoroalkenes. Using visible-light-activated catalysts in conjunction with an arsenal of carbon-radical precursors, an array of trifluoromethyl-substituted alkenes undergoes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b49a5f2fb7c3dfb497e186244e93bd
https://doi.org/10.1002/anie.201709487
https://doi.org/10.1002/anie.201709487
Publikováno v:
The Journal of organic chemistry. 84(5)
Decarboxylative elimination of easily accessible N-acyl amino acids to provide enamide and enecarbamate building blocks has been realized through the combination of an organophotoredox catalyst and copper acetate as the terminal oxidant. This operati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051dadca6269767949de0a532cd1d675
https://pubmed.ncbi.nlm.nih.gov/30785754
https://pubmed.ncbi.nlm.nih.gov/30785754
Autor:
James P. Phelan, Katelyn Billings, Andrew J. Peat, Simon B. Lang, Simon Berritt, Gary A. Molander, Lijun Fan, Jaehoon Sim
Publikováno v:
Journal of the American Chemical Society. 141(8)
DNA-encoded library (DEL) technology is a powerful tool commonly used by the pharmaceutical industry for the identification of compounds with affinity to biomolecular targets. Success in this endeavor lies in sampling diverse chemical libraries. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff92fe5e0826448c01f7f4759ffad0e
https://pubmed.ncbi.nlm.nih.gov/30753065
https://pubmed.ncbi.nlm.nih.gov/30753065
Autor:
Ryan Dykstra, James P. Phelan, Jordan S. Compton, Gary A. Molander, Christopher B. Kelly, Osvaldo Gutierrez, Simon B. Lang
Publikováno v:
Journal of the American Chemical Society. 140(25)
A bench-top stable, bifunctional reagent for the redox-neutral cyclopropanation of olefins has been developed. Triethylammonium bis(catecholato)iodomethylsilicate can be readily prepared on multigram scale. Using this reagent in combination with an o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d9b0a0f39467eb45f23b9b9811ca3d
https://pubmed.ncbi.nlm.nih.gov/29916711
https://pubmed.ncbi.nlm.nih.gov/29916711