Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Simon Allard"'
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2021)
Cue-evoked persistent activity is neural activity that persists beyond stimulation of a sensory cue and has been described in many regions of the brain, including primary sensory areas. Nonetheless, the functional role that persistent activity plays
Externí odkaz:
https://doaj.org/article/256d7d58ca14479ca4d7091c06952c8f
Autor:
M. Florencia Iulita, M. Beatriz Bistué Millón, Rowan Pentz, Lisi Flores Aguilar, Sonia Do Carmo, Simon Allard, Bernadeta Michalski, Edward N. Wilson, Adriana Ducatenzeiler, Martin A. Bruno, Margaret Fahnestock, A. Claudio Cuello
Publikováno v:
Neurobiology of Disease, Vol 108, Iss , Pp 307-323 (2017)
Evidence from human neuropathological studies indicates that the levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are compromised in Alzheimer's disease. However, the causes and temporal (pathology-de
Externí odkaz:
https://doaj.org/article/6c0c94eebe334f3fa038f02a235a8d3c
Autor:
Simon Allard, Maria Florencia Iulita, Lisi Flores Aguilar, Do Carmo S, Lindsay A. Welikovitch, Adriana Ducatenzeiler, Edward N. Wilson, Morgan K. Foret, A.C. Cuello, Emmerson Jt, Hélène Hall, Adam R. Marks, D T Jia
Publikováno v:
Journal of Alzheimer's disease : JAD. 73(2)
Epidemiological, preclinical, and clinical studies have suggested a role for microdose lithium in reducing Alzheimer's disease (AD) risk by modulating key mechanisms associated with AD pathology. The novel microdose lithium formulation, NP03, has dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2eccc81a2be1f9c9a63e337ee808c4
https://pubmed.ncbi.nlm.nih.gov/31868669
https://pubmed.ncbi.nlm.nih.gov/31868669
Publikováno v:
Cereb Cortex
The primary sensory cortex has historically been studied as a low-level feature detector, but has more recently been implicated in many higher-level cognitive functions. For instance, after an animal learns that a light predicts water at a fixed dela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ffdc7ba528eb065b141dceed10e868
Publikováno v:
Rheumatology Advances in Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e468ba2777ca89db2d89a02525a0b311
http://europepmc.org/articles/PMC6652636
http://europepmc.org/articles/PMC6652636
Publikováno v:
Neurobiology of aging. 67
The degeneration of basal forebrain cholinergic neurons (BFCNs) in Alzheimer's disease (AD) contributes to cognitive impairment. Nerve growth factor (NGF) secreted in the cerebral cortex is necessary for the phenotypic maintenance of BFCNs. AD is ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1447fe11aa1daa56b88df1bd29ffcdbb
https://pubmed.ncbi.nlm.nih.gov/29609077
https://pubmed.ncbi.nlm.nih.gov/29609077
Autor:
Luisa S.B. Pimentel, Simon Allard, A. Claudio Cuello, Sonia Do Carmo, M. Florencia Iulita, Adriana Ducatenzeiler, Cecilia E. Hanzel, Alexa Pichet-Binette
Publikováno v:
Neurobiology of Aging. 35:2249-2262
Chronic brain inflammation is associated with Alzheimer's disease (AD) and is classically attributed to amyloid plaque deposition. However, whether the amyloid pathology can trigger early inflammatory processes before plaque deposition remains a matt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a468b8fdb1a51c3fdcef89af21e58263
https://doi.org/10.1016/j.neurobiolaging.2014.03.026
https://doi.org/10.1016/j.neurobiolaging.2014.03.026
Autor:
Edward N. Wilson, Adam R. Marks, A. Claudio Cuello, Sonia Do Carmo, Adriana Ducatenzeiler, Joseph Windheim, Simon Allard, M. Florencia Iulita
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20383d6168e4da0ae3f722785a144ff3
https://doi.org/10.1016/j.jalz.2016.06.1704
https://doi.org/10.1016/j.jalz.2016.06.1704
Autor:
A. Claudio Cuello, Andrew R. Abela, Edward N. Wilson, Simon Allard, Adriana Ducatenzeiler, Lindsay A. Welikovitch, Adam R. Marks, Yogita Chudasama, Sonia Do Carmo
Publikováno v:
Cerebral Cortex. 27
In Alzheimer disease (AD), the accumulation of amyloid beta (Aβ) begins decades before cognitive symptoms and progresses from intraneuronal material to extracellular plaques. To date, however, the precise mechanism by which the early buildup of Aβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef709b664a6f1f2faf90f7ee0ab59cf7
https://doi.org/10.1093/cercor/bhv332
https://doi.org/10.1093/cercor/bhv332
Publikováno v:
Neurobiology of Aging. 33:1466-1480
It is well established that the cerebral cortex undergoes extensive remodeling in aging. In this study, we used behaviorally characterized rats to correlate age-related morphological changes with cognitive impairment. For this, young and aged animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4fb5b8e42bfc15f4ee2b37211ee63c
https://doi.org/10.1016/j.neurobiolaging.2010.10.011
https://doi.org/10.1016/j.neurobiolaging.2010.10.011