Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Simon A. Thom"'
Autor:
Boram Gu, Andris Piebalgs, Yu Huang, Colin Longstaff, Alun D. Hughes, Rongjun Chen, Simon A. Thom, Xiao Yun Xu
Publikováno v:
Pharmaceutics, Vol 11, Iss 3, p 111 (2019)
Thrombolytic therapy is one of the medical procedures in the treatment of acute ischaemic stroke (AIS), whereby the tissue plasminogen activator (tPA) is intravenously administered to dissolve the obstructive blood clot. The treatment of AIS by throm
Externí odkaz:
https://doaj.org/article/94bc751907694622929341af8f92261d
Publikováno v:
PeerJ, Vol 7, p e7119 (2019)
The optic disc (OD) in retinal fundus images is widely used as a reference in computer-based systems for the measurement of the severity of retinal disease. A number of algorithms have been published in the past 5 years to locate and measure the OD i
Externí odkaz:
https://doaj.org/article/d0fedb2a978e4db290eb1a17c733ac75
Autor:
Sashiananthan Ganesananthan, Christopher A Rajkumar, Michael Foley, David Thompson, Alexandra N Nowbar, Henry Seligman, Ricardo Petraco, Sayan Sen, Sukhjinder Nijjer, Simon A Thom, Roland Wensel, John Davies, Darrel Francis, Matthew Shun-Shin, James Howard, Rasha Al-Lamee
Publikováno v:
European Heart Journal. 43:3132-3145
Aims Oxygen-pulse morphology and gas exchange analysis measured during cardiopulmonary exercise testing (CPET) has been associated with myocardial ischaemia. The aim of this analysis was to examine the relationship between CPET parameters, myocardial
Autor:
Alun D Hughes, Raj Bathula, Chloe Park, Therese Tillin, Nicholas Wit, Simon McG Thom, Nish Chaturvedi
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76680 (2013)
People of South Asian descent have an increased risk of cardiovascular disease (CVD) and diabetes, but little is known about the microcirculation in South Asian people despite evidence that this plays an important role in the aetiology of CVD. We com
Externí odkaz:
https://doaj.org/article/60c31b3d8dac4a9c9e770c947577fc5a
Autor:
Mark Jackson, Nigel B. Wood, Shunzhi Zhao, Alexander Augst, John H. Wolfe, Wladyslaw M.W. Gedroyc, Alun D. Hughes, Simon A.McG. Thom, Xiao Y. Xu
Publikováno v:
Artery Research, Vol 3, Iss 1 (2009)
Background: Venous grafts commonly develop myointimal hyperplasia, which can lead to stenoses and, ultimately, with expression of adhesion molecules, lumenal occlusion. The aim of the present study was to investigate whether wall shear stress measure
Externí odkaz:
https://doaj.org/article/e1d65245dbb54b7aab59098247cbb330
Autor:
Rasha Al-Lamee, David Thompson, Hakim-Moulay Dehbi, Sayan Sen, Kare Tang, John Davies, Thomas Keeble, Michael Mielewczik, Raffi Kaprielian, Iqbal S Malik, Sukhjinder S Nijjer, Ricardo Petraco, Christopher Cook, Yousif Ahmad, James Howard, Christopher Baker, Andrew Sharp, Robert Gerber, Suneel Talwar, Ravi Assomull, Jamil Mayet, Roland Wensel, David Collier, Matthew Shun-Shin, Simon A Thom, Justin E Davies, Darrel P Francis, Amarjit Sethi, Punit Ramrakha, Rodney Foale, Ramzi Khamis, Nearchos Hadjiloizou, Masood Khan, Jaspal Kooner, Michael Bellamy, Ghada Mikhail, Piers Clifford, Peter O'Kane, Terry Levy, Rosie Swallow
Publikováno v:
The Lancet. 391:31-40
Summary Background Symptomatic relief is the primary goal of percutaneous coronary intervention (PCI) in stable angina and is commonly observed clinically. However, there is no evidence from blinded, placebo-controlled randomised trials to show its e
Autor:
Rasha, Al-Lamee, James P, Howard, Matthew J, Shun-Shin, David, Thompson, Hakim-Moulay, Dehbi, Sayan, Sen, Sukhjinder, Nijjer, Ricardo, Petraco, John, Davies, Thomas, Keeble, Kare, Tang, Iqbal S, Malik, Christopher, Cook, Yousif, Ahmad, Andrew S P, Sharp, Robert, Gerber, Christopher, Baker, Raffi, Kaprielian, Suneel, Talwar, Ravi, Assomull, Graham, Cole, Niall G, Keenan, Gajen, Kanaganayagam, Joban, Sehmi, Roland, Wensel, Frank E, Harrell, Jamil, Mayet, Simon A, Thom, Justin E, Davies, Darrel P, Francis
Publikováno v:
Circulation. 138(17)
There are no data on how fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are associated with the placebo-controlled efficacy of percutaneous coronary intervention (PCI) in stable single-vessel coronary artery disease.We report t
Autor:
Simon M Thom, Alun D. Hughes, Peter S. Lacy, Bryan Williams, Michael F. O'Rourke, H. Thurston, Kennedy Cruickshank, David Collier, Alice Stanton
Publikováno v:
Circulation. 113:1213-1225
Background— Different blood pressure (BP)–lowering drugs could have different effects on central aortic pressures and thus cardiovascular outcome despite similar effects on brachial BP. The Conduit Artery Function Evaluation (CAFE) study, a subst
Autor:
Morris J. Brown, Gordon T. McInnes, Peter S. Sever, Neil R Poulter, Bryan Williams, John F. Potter, Simon M Thom, Mark David McGregor Davis
Publikováno v:
BMJ. 328:634-640
Much new evidence has emerged on the importance of blood pressure as a risk factor for cardiovascular disease; the importance of lifestyle measures for the prevention and treatment of hypertension; the efficacy and safety of different drug classes; m
Autor:
Loreto Boix, Nicholas P.J. Brindle, Allan Sirsjö, Anders Gidlöf, Stefania Lucia Nori, Xuenong Bo, Maria Carlsson, Joan Rodés, Simon McG. Thom, Julie A.A. Borland, Jaime Bosch, Jordi Bruix, Rajabrata Sarkar, Mohamed Amrani, Yuri Bogdanov, Magdi H. Yacoub, Gregory J. Dusting, Wladimiro Jiménez, Peter Söderkvist, Eberhard Uhl, Lorenzo Fumagalli, Francisca Rivera, Heather Glazebrook, Martin Öst, P. Görög, Geoffrey Burnstock, Timothy Hatch, Albert Leivas, Vicente Arroyo, Iren B. Kovacs, R. Clinton Webb, Haruyo Hickey, Zhan-Li Yin, Adrian H. Chester, Karen J.M. Morrison
Publikováno v:
Journal of Vascular Research. 35:194-233