Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Simon A. Fox"'
Autor:
Ravi Teja Chitturi Suryaprakash, Kate Shearston, Camile S. Farah, Simon A. Fox, Muhammad Munir Iqbal, Ulrich Kadolsky, Xiao Zhong, Alka Saxena, Omar Kujan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4096 (2023)
This study aimed to develop an in vitro three-dimensional (3D) cell culture model of oral carcinogenesis for the rapid, scalable testing of chemotherapeutic agents. Spheroids of normal (HOK) and dysplastic (DOK) human oral keratinocytes were cultured
Externí odkaz:
https://doaj.org/article/794a2ea9e00b487bad7640b5e1022cd6
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 464 (2022)
Relapse after surgery for oral squamous cell carcinoma (OSCC) contributes significantly to morbidity, mortality and poor outcomes. The current histopathological diagnostic techniques are insufficiently sensitive for the detection of oral cancer and m
Externí odkaz:
https://doaj.org/article/0cbc5fb275f54a738500218909dd56a9
Publikováno v:
Journal of Oral Pathology & Medicine.
Publikováno v:
Archives of Biochemistry and Biophysics. 740:109583
Autor:
Andrew J. Dalley, Kate Shearston, Nigel C. Bennett, Maryam Jessri, Camile S. Farah, Simon A. Fox
Publikováno v:
Oral Oncology. 96:42-50
Objectives To map the genomic pathways of patients with oral leukoplakia (OLK) which transformed to cancer (progressive) and those which did not (non-progressive), and to compare their exomic profiles. Materials and methods Whole exome sequencing was
Autor:
Simon A. Fox, Camile S. Farah
Publikováno v:
Oral Diseases. 25:1715-1723
Objective The molecular mechanisms underlying the development of dysplasia in leukoplakia are unknown. We used RNA sequencing to examine the molecular and biological pathway differences in oral leukoplakia with and without oral epithelial dysplasia.
Publikováno v:
Oral oncology. 119
Objectives Oral Lichenoid Dysplasia (OLD) is a controversial histological term applied to lesions that display features of oral lichen planus (OLP) and oral epithelial dysplasia (OED). In this study we investigated the molecular profiles of OLD, OLP
Autor:
Kate Shearston, Naisana Seyedasli, Munira Xaymardan, Simon A. Fox, Giuseppe Pantaleo, Antonio Celentano, Camile S. Farah
Publikováno v:
Regenerative Approaches in Dentistry ISBN: 9783030598082
Stem cells are undifferentiated cells, which possess self-renewal properties and can produce specialized cells of multiple lineages. In addition to other stem cells from various anatomical locations within the maxillofacial complex, the oral cavity h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39406b77265a016556c2691384c5dec4
https://doi.org/10.1007/978-3-030-59809-9_10
https://doi.org/10.1007/978-3-030-59809-9_10
Publikováno v:
Am J Trop Med Hyg
Eosinophilic meningitis is classically caused by Angiostrongylus cantonensis. Treatment usually includes supportive care and corticosteroids. Anthelminthic drugs are often avoided because of the risk of an inflammatory reaction to dying larvae. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa82681f5b2590c3bb7fc6090d4a902d
https://europepmc.org/articles/PMC7866322/
https://europepmc.org/articles/PMC7866322/
Autor:
Peter J. Atkinson, Hugh Nuthall, Simon A. Fox, Diego Gomez-Nicola, Alan R. Prescott, Elena Pipi, Eric Karran, Janet Brownlees, Dorte Faust, Carol Routledge, Fergus Buchanan, Juliane Obst, Liana M Barkwill, Ivette Gonzalez-Rivera, V. Hugh Perry, Debra L. Taylor, Emilie Simon, Maria Martin-Estebane
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
The proliferation and activation of microglia, the resident macrophages in the brain, is a hallmark of many neurodegenerative diseases such as Alzheimer's disease (AD) and prion disease. Colony stimulating factor 1 receptor (CSF1R) is critically invo