Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Simon A Joosse"'
Publikováno v:
Cells, Vol 13, Iss 16, p 1382 (2024)
Centrosomal Protein 55 (CEP55) exhibits various oncogenic activities; it regulates the PI3K-Akt-pathway, midbody abscission, and chromosomal instability (CIN) in cancer cells. Here, we analyzed the mechanism of how CEP55 controls CIN in ovarian and b
Externí odkaz:
https://doaj.org/article/ccefbab300754954ba207a979ca3abda
Autor:
Maha Elazezy, Katharina Prieske, Lan Kluwe, Leticia Oliveira‐Ferrer, Sven Peine, Volkmar Müller, Linn Woelber, Barbara Schmalfeldt, Klaus Pantel, Simon A. Joosse
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3615-3625 (2021)
Methylation of the BRCA1 promoter is an epigenetic gene expression regulator and is frequently observed in ovarian cancer; however, conversion of methylation status is thought to drive disease recurrence. Therefore, longitudinal monitoring of methyla
Externí odkaz:
https://doaj.org/article/d5b14d9287144f21a36580691214ee91
Autor:
Malte Mohme, Cecile L. Maire, Simon Schliffke, Simon A. Joosse, Malik Alawi, Jakob Matschke, Ulrich Schüller, Judith Dierlamm, Tobias Martens, Klaus Pantel, Sabine Riethdorf, Katrin Lamszus, Manfred Westphal
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Peripheral metastases of glioblastoma (GBM) are very rare despite the ability of GBM cells to pass through the blood-brain barrier and be disseminated through the peripheral blood. Here, we describe a detailed genetic and immunological chara
Externí odkaz:
https://doaj.org/article/af5e7fd562514538833c9008e7c88964
Autor:
Alexey S. Rzhevskiy, Alina Y. Kapitannikova, Denis V. Butnaru, Evgeniy V. Shpot, Simon A. Joosse, Andrei V. Zvyagin, Majid Ebrahimi Warkiani
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3115 (2022)
Currently, sensitive and specific methods for the detection and prognosis of early stage PCa are lacking. To establish the diagnosis and further identify an appropriate treatment strategy, prostate specific antigen (PSA) blood test followed by tissue
Externí odkaz:
https://doaj.org/article/618bb3529b314a97a8a67ca0537f7017
Autor:
Carlotta Riebensahm, Simon A. Joosse, Malte Mohme, Annkathrin Hanssen, Jakob Matschke, Yvonne Goy, Isabell Witzel, Katrin Lamszus, Jolanthe Kropidlowski, Cordula Petersen, Anja Kolb-Kokocinski, Sascha Sauer, Kerstin Borgmann, Markus Glatzel, Volkmar Müller, Manfred Westphal, Sabine Riethdorf, Klaus Pantel, Harriet Wikman
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Background The incidence of brain metastases in breast cancer (BCBM) patients is increasing. These patients have a very poor prognosis, and therefore, identification of blood-based biomarkers, such as circulating tumor cells (CTCs), and unde
Externí odkaz:
https://doaj.org/article/9ce323027a994649b8033de0443befc4
Autor:
Claudia Koch, Andra Kuske, Simon A Joosse, Gökhan Yigit, George Sflomos, Sonja Thaler, Daniel J Smit, Stefan Werner, Kerstin Borgmann, Sebastian Gärtner, Parinaz Mossahebi Mohammadi, Laura Battista, Laure Cayrefourcq, Janine Altmüller, Gabriela Salinas‐Riester, Kaamini Raithatha, Arne Zibat, Yvonne Goy, Leonie Ott, Kai Bartkowiak, Tuan Zea Tan, Qing Zhou, Michael R Speicher, Volkmar Müller, Tobias M Gorges, Manfred Jücker, Jean‐Paul Thiery, Cathrin Brisken, Sabine Riethdorf, Catherine Alix‐Panabières, Klaus Pantel
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
Abstract Functional studies giving insight into the biology of circulating tumor cells (CTCs) remain scarce due to the low frequency of CTCs and lack of appropriate models. Here, we describe the characterization of a novel CTC‐derived breast cancer
Externí odkaz:
https://doaj.org/article/6fcb45740e9c4955a376a11179160a9e
Autor:
Maha Elazezy, Simon A. Joosse
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 16, Iss , Pp 370-378 (2018)
Precision medicine in the clinical management of cancer may be achieved through the diagnostic platform called “liquid biopsy”. This method utilizes the detection of biomarkers in blood for prognostic and predictive purposes. One of the latest bl
Externí odkaz:
https://doaj.org/article/6e559c56886f4b3eb2e1467ac8fbd3d3
Autor:
Desiree Loreth, Moritz Schuette, Jenny Zinke, Malte Mohme, Andras Piffko, Svenja Schneegans, Julia Stadler, Melanie Janning, Sonja Loges, Simon A. Joosse, Katrin Lamszus, Manfred Westphal, Volkmar Müller, Markus Glatzel, Jakob Matschke, Christoffer Gebhardt, Stefan W. Schneider, Iwona Belczacka, Beate Volkmer, Rüdiger Greinert, Marie-Laure Yaspo, Patrick N. Harter, Klaus Pantel, Harriet Wikman
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6993 (2021)
Up to 40% of advance lung, melanoma and breast cancer patients suffer from brain metastases (BM) with increasing incidence. Here, we assessed whether circulating tumor cells (CTCs) in peripheral blood can serve as a disease surrogate, focusing on CD4
Externí odkaz:
https://doaj.org/article/16509b4c9bab441cbd41a1b4a6e22c5e
Autor:
Malte Mohme, Sabine Riethdorf, Marc Dreimann, Stefan Werner, Cecile L. Maire, Simon A. Joosse, Frederic Bludau, Volkmar Mueller, Rui P. L. Neves, Nikolas H. Stoecklein, Katrin Lamszus, Manfred Westphal, Klaus Pantel, Harriet Wikman, Sven O. Eicker
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Cement augmentation via percutaneous vertebroplasty or kyphoplasty for treatment of spinal metastasis is a well-established treatment option. We assessed whether elevated intrametastatic pressure during cement augmentation results in an incr
Externí odkaz:
https://doaj.org/article/91d6cac1f9e843848dfa4e20a239fc07
Autor:
Klaus Pantel, Thomas Krahn, Christian Schumann, Oliver von Ahsen, Nora Brychta, Stephen Jackson, Harriet Wikman, Klaus Lücke, Johannes Tucholski, Sabine Riethdorf, Simon A. Joosse, Thomas Schalk, Nicole Penkalla, Tobias M. Gorges
Purpose: The use of circulating tumor cells (CTC) as “liquid biopsy” is limited by the very low yield of CTCs available for subsequent analyses. Most in vitro approaches rely on small sample volumes (5–10 mL).Experimental Design: Here, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1e62a439d0b145178028853bc432be
https://doi.org/10.1158/1078-0432.c.6523296.v1
https://doi.org/10.1158/1078-0432.c.6523296.v1