Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Simon, de Denus"'
Autor:
Anna Levinsson, Simon de Denus, Johanna Sandoval, Louis-Philippe Lemieux Perreault, Joëlle Rouleau, Jean-Claude Tardif, Julie Hussin, Marie-Pierre Dubé
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Gender captures social components beyond biological sex and can add valuable insight to health studies in populations. However, assessment of gender typically relies on questionnaires which may not be available. The aim of this study is to c
Externí odkaz:
https://doaj.org/article/5ec3b8e589484f5a82d6a621193c99b3
Autor:
Marie-Pierre Dubé, Audrey Lemaçon, Amina Barhdadi, Louis-Philippe Lemieux Perreault, Essaïd Oussaïd, Géraldine Asselin, Sylvie Provost, Maxine Sun, Johanna Sandoval, Marc-André Legault, Ian Mongrain, Anick Dubois, Diane Valois, Emma Dedelis, Jennifer Lousky, Julie Choi, Elisabeth Goulet, Christiane Savard, Lea-Mei Chicoine, Mariève Cossette, Malorie Chabot-Blanchet, Marie-Claude Guertin, Simon de Denus, Nadia Bouabdallaoui, Richard Marchand, Zohar Bassevitch, Anna Nozza, Daniel Gaudet, Philippe L. L’Allier, Julie Hussin, Guy Boivin, David Busseuil, Jean-Claude Tardif
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract We conducted a genome-wide association study of time to remission of COVID-19 symptoms in 1723 outpatients with at least one risk factor for disease severity from the COLCORONA clinical trial. We found a significant association at 5p13.3 (rs
Externí odkaz:
https://doaj.org/article/22ad144ba1304827b38809d5ea8a9606
Autor:
Sylvie Perreault, Alice Dragomir, Robert Côté, Aurélie Lenglet, Simon de Denus, Marc Dorais, Brian White-Guay, James Brophy, Mireille E. Schnitzer, Marie-Pierre Dubé, Jean-Claude Tardif
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Aims: Observational studies of various dose levels of direct oral anticoagulants (DOACs) for patients with atrial fibrillation (AF) found that a high proportion of patients received a dose lower than the target dose tested in randomized controlled tr
Externí odkaz:
https://doaj.org/article/4e8f4f329cac4385b69b9b4e951ed5f4
Autor:
Jessica Hindi, Marc‐Olivier Pilon, Maxime Meloche, Grégoire Leclair, Essaïd Oussaïd, Isabelle St‐Jean, Martin Jutras, Marie‐Josée Gaulin, Ian Mongrain, David Busseuil, Jean Lucien Rouleau, Jean‐Claude Tardif, Marie‐Pierre Dubé, Simon de Denus
Publikováno v:
Clinical and Translational Science. 16:872-885
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b5c308daaf998db29838ff68914b79
https://doi.org/10.1111/cts.13497
https://doi.org/10.1111/cts.13497
Autor:
Marilyne, Jarjour, Jacinthe, Leclerc, Nadia, Bouabdallaoui, Charaf, Ahnadi, Denis, Brouillette, Simon, de Denus, Annik, Fortier, Patrick, Garceau, Geneviève, Giraldeau, Serge, Lepage, Mark, Liszkowski, Eileen, O'Meara, Marie-Claude, Parent, Normand, Racine, Maxime, Tremblay-Gravel, Michel, White, Jean-Lucien, Rouleau, Anique, Ducharme
Publikováno v:
International Journal of Cardiology. 370:300-308
In heart failure, specific target doses for each drug are recommended, but some patients receive suboptimal dosing, others are undertreated or remain chronically in a titration phase, despite having no apparent contraindication or intolerance. We ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8637031fa1657ef28fcda31acbf84603
https://doi.org/10.1016/j.ijcard.2022.09.058
https://doi.org/10.1016/j.ijcard.2022.09.058
Autor:
Marc-André Legault, Johanna Sandoval, Sylvie Provost, Amina Barhdadi, Louis-Philippe Lemieux Perreault, Sonia Shah, R Thomas Lumbers, Simon de Denus, Benoit Tyl, Jean-Claude Tardif, Marie-Pierre Dubé
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236193 (2020)
BackgroundNaturally occurring human genetic variants provide a valuable tool to identify drug targets and guide drug prioritization and clinical trial design. Ivabradine is a heart rate lowering drug with protective effects on heart failure despite i
Externí odkaz:
https://doaj.org/article/52a9a7b767ca4bfc96f14048d78d9942
Autor:
Nadia Iannino, Amine Nasri, Agnès Räkel, Anique Ducharme, Kim Lachance, Normand Racine, Simon de Denus, Maxime Tremblay-Gravel, Annik Fortier, Michel White
Publikováno v:
Journal of Transplantation, Vol 2018 (2018)
Background. Recent changes in the demographic of cardiac donors and recipients have modulated the rate and risk, associated with posttransplant diabetes mellitus (PTDM). We investigated the secular trends of the risk of PTDM at 1 year and 3 years aft
Externí odkaz:
https://doaj.org/article/5fba677db7134f409c8a25a7d2963079
Autor:
Zohar Bassevitch, Anna Nozza, Marie-Pierre Dubé, Maxine Sun, Jennifer Lousky, Julie Hussin, Malorie Chabot-Blanchet, Emma Dedelis, Anick Dubois, Marc-André Legault, Diane Valois, Lea Mei Chicoine, Christiane Savard, Audrey Lemaçon, Johanna Sandoval, Julie Choi, Daniel Gaudet, Ian Mongrain, Sylvie Provost, Louis Philippe Lemieux Perreault, Simon de Denus, R. Marchand, Guy Boivin, Amina Barhdadi, David Busseuil, Nadia Bouabdallaoui, Philippe L. L’Allier, Mariève Cossette, Marie Claude Guertin, Géraldine Asselin, Elisabeth Goulet, Jean-Claude Tardif, Essaïd Oussaïd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
We conducted a genome-wide association study of time to remission of COVID-19 symptoms in 1723 outpatients with at least one risk factor for disease severity from the COLCORONA clinical trial. We found a significant association at 5p13.3 (rs1173773;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a6534046888b83e0be281612006ca8
https://doaj.org/article/22ad144ba1304827b38809d5ea8a9606
https://doaj.org/article/22ad144ba1304827b38809d5ea8a9606
Autor:
Simon de Denus, Michael R. Zile, Eileen O'Meara, Jean L. Rouleau, Corrado De Marco, Scott D. Solomon, Martin G. Sirois, Thao Huynh, Akshay S. Desai, Brian Claggett, Bertram Pitt, Marc A. Pfeffer
Publikováno v:
ESC Heart Failure, Vol 8, Iss 2, Pp 1130-1138 (2021)
ESC Heart Failure
ESC Heart Failure
Aims Diabetes mellitus (DM) is common in heart failure with preserved ejection fraction (HFpEF). Patients with DM and heart failure with reduced ejection fraction have higher levels of cardiac, profibrotic, and proinflammatory biomarkers relative to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e25fa4a22bc44f039c3433483a20be8
https://doaj.org/article/b070388439fb4ff99e7b2abea15e1756
https://doaj.org/article/b070388439fb4ff99e7b2abea15e1756
Autor:
Alice Dragomir, Marie-Pierre Dubé, Aurélie Lenglet, Sylvie Perreault, B. White-Guay, James M. Brophy, Robert Côté, Marc Dorais, Simon de Denus, Jean-Claude Tardif, Mireille E. Schnitzer
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 41:379-393
Study objective Observational studies assessing direct oral anticoagulant (DOACs) dosage in atrial fibrillation (AF) reported that a lower proportion of patients received high-dose DOACs compared to those in randomized controlled trials (RCTs). Effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30d90fe01bd44d195a4502798384d7a
https://doi.org/10.1002/phar.2509
https://doi.org/10.1002/phar.2509