Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Simon, Strietholt"'
Autor:
Svetlana Frank, Marvin A Peters, Corinna Wehmeyer, Simon Strietholt, Christina Koers-Wunrau, Jessica Bertrand, Marianne Heitzmann, Anja Hillmann, Joanna Sherwood, Christine Seyfert, Steffen Gay, Thomas Pap
Publikováno v:
Annals of the Rheumatic Diseases. 72:1874-1881
Objective Based on previous data that have linked the small ubiquitin-like modifier-1 (SUMO-1) to the pathogenesis of rheumatoid arthritis (RA), we have investigated the expression of the highly homologous SUMO family members SUMO-2/3 in human RA and
Autor:
Ingmar Meinecke, Géza Pap, Heidi Mendoza, Steffen Drange, Stephan Ender, Simon Strietholt, Renate E. Gay, Christine Seyfert, Barbara Ink, Steffen Gay, Thomas Pap, Marvin A. Peters
Publikováno v:
Arthritis & Rheumatism. 60:2065-2070
Objective To study the expression of small ubiquitin-like modifier 1 (SUMO-1) in aseptic loosening of prosthesis implants and to investigate its role in regulating the susceptibility of prosthesis-loosening fibroblast-like synoviocytes (FLS) to Fas-i
Autor:
Beate Eckes, Svetlana Frank, Doreen Wendholt, Wim B. van den Berg, Simon Strietholt, Adelheid Korb-Pap, Noreen Pundt, Leo A. B. Joosten, Marvin A. Peters, Thomas Pap, George Kollias
Publikováno v:
Arthritis and Rheumatism, 64, 1359-68
Arthritis and Rheumatism, 64, 5, pp. 1359-68
Arthritis and Rheumatism, 64, 5, pp. 1359-68
Item does not contain fulltext OBJECTIVE: Integrin alpha2beta1 functions as a major receptor for type I collagen on different cell types, including fibroblasts and inflammatory cells. Although in vitro data suggest a role for alpha2beta1 integrin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f13eb77271bcb04197bc107c6c7a78a
https://www.ncbi.nlm.nih.gov/pubmed/22083543
https://www.ncbi.nlm.nih.gov/pubmed/22083543
Autor:
Hanna Maciejewska-Rodrigues, Emmanuel Karouzakis, Simon Strietholt, Hossein Hemmatazad, Michel Neidhart, Caroline Ospelt, Renate E. Gay, Beat A. Michel, Thomas Pap, Steffen Gay, Astrid Jüngel
Publikováno v:
Journal of Autoimmunity
Journal of Autoimmunity; Vol 35
Journal of Autoimmunity; Vol 35
The aggressive phenotype of RA synovial fibroblasts (RASF) is characterised by the increased expression of matrix metalloproteinase (MMP)-1 as well as the small ubiquitin like modifier (SUMO)-1 and decreased expression of SUMO-specific protease SENP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551cb11feb248871fdd38cd7c546333f
https://www.zora.uzh.ch/id/eprint/28729/
https://www.zora.uzh.ch/id/eprint/28729/
Autor:
Ingmar, Meinecke, Géza, Pap, Heidi, Mendoza, Steffen, Drange, Stephan, Ender, Simon, Strietholt, Renate E, Gay, Christine, Seyfert, Barbara, Ink, Steffen, Gay, Thomas, Pap, Marvin A, Peters
Publikováno v:
Arthritis and rheumatism. 60(7)
To study the expression of small ubiquitin-like modifier 1 (SUMO-1) in aseptic loosening of prosthesis implants and to investigate its role in regulating the susceptibility of prosthesis-loosening fibroblast-like synoviocytes (FLS) to Fas-induced apo
Publikováno v:
Arthritis Research & Therapy
Over the last decades, genetic factors for rheumatoid diseases like the HLA haplotypes have been studied extensively. However, during the past years of research, it has become more and more evident that the influence of epigenetic processes on the de
Autor:
Thomas Pap, Marvin A. Peters, D Wendholt, Svetlana Frank, George Kollias, Adelheid Korb, B Eckes, Simon Strietholt
Publikováno v:
Annals of the Rheumatic Diseases. 69:A22-A23
Integrins are the main receptors for cell-matrix interactions and integrin signalling is critical for a variety of cellular functions such as adhesion, cell spreading and inflammatory responses. α2β1 integrin functions as a major receptor for type
Autor:
Svetlana Frank, Thomas Pap, Simon Strietholt, Anja Hillmann, Marvin A. Peters, George Kollias
Publikováno v:
Annals of the Rheumatic Diseases. 71:159.3-159
Background It has been shown previousely that posttranslational protein modification through SUMOylation is enhanced in rheumatoid athritis synovial fibroblasts (RASF) compared to osteoathritis synovial fibroblasts (OASF) and that higher levels of SU
Publikováno v:
Annals of the Rheumatic Diseases. 69:A30-A30
SUMO-2/3 belongs to the small ubiquitin-related modifier family of proteins that have been implicated in many biological functions such as intracellular protein transport, control of gene expression and stability of proteins. The authors have previou
Autor:
Svetlana Frank, N Pundt, Simon Strietholt, S Ender, George Kollias, Marvin A. Peters, Thomas Pap
Publikováno v:
Annals of the Rheumatic Diseases. 69:A17-A17
Small ubiquitin-related modifiers (SUMOs) are key players in post-translational protein modifications and regulate various cellular processes such as cell division or apoptosis. SUMOylation is regulated by a family of SUMO specific proteases (SENPs)