Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Simon, Rauber"'
Autor:
Pia Sinner, Katrin Peckert-Maier, Hashem Mohammadian, Christine Kuhnt, Christina Draßner, Vasiliki Panagiotakopoulou, Simon Rauber, Mathias Linnerbauer, Zhana Haimon, Dmytro Royzman, Deborah Kronenberg-Versteeg, Andreas Ramming, Alexander Steinkasserer, Andreas B. Wild
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Microglial activation during neuroinflammation is crucial for coordinating the immune response against neuronal tissue, and the initial response of microglia determines the severity of neuro-inflammatory diseases. The CD83 molecule has been
Externí odkaz:
https://doaj.org/article/9a4547d3e8bc4990bcfb3139d1b9c766
Autor:
Lisa Kohl, Md Nur A Alam Siddique, Barbara Bodendorfer, Raffaela Berger, Annica Preikschat, Christoph Daniel, Martha Ölke, Elisabeth Liebler‐Tenorio, Jan Schulze‐Luehrmann, Michael Mauermeir, Kai‐Ting Yang, Inaya Hayek, Manuela Szperlinski, Jennifer Andrack, Ulrike Schleicher, Aline Bozec, Gerhard Krönke, Peter J Murray, Stefan Wirtz, Masahiro Yamamoto, Valentin Schatz, Jonathan Jantsch, Peter Oefner, Daniel Degrandi, Klaus Pfeffer, Katja Mertens‐Scholz, Simon Rauber, Christian Bogdan, Katja Dettmer, Anja Lührmann, Roland Lang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Infection with the intracellular bacterium Coxiella (C.) burnetii can cause chronic Q fever with severe complications and limited treatment options. Here, we identify the enzyme cis‐aconitate decarboxylase 1 (ACOD1 or IRG1) and its product
Externí odkaz:
https://doaj.org/article/1b69987f304e4114b08d5e4633d04bb6
Autor:
Ariella Zehender, Yi-Nan Li, Neng-Yu Lin, Adrian Stefanica, Julian Nüchel, Chih-Wei Chen, Hsiao-Han Hsu, Honglin Zhu, Xiao Ding, Jingang Huang, Lichong Shen, Andrea-Hermina Györfi, Alina Soare, Simon Rauber, Christina Bergmann, Andreas Ramming, Markus Plomann, Beate Eckes, Georg Schett, Jörg H. W. Distler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Uncontrolled activation of fibroblasts contributes to tissue fibrosis and organ dysfunction. Here the authors demonstrate that the epigenetic control of autophagy is disturbed by a TGFβ-dependent downregulation of MYST1 in systemic sclerosis patient
Externí odkaz:
https://doaj.org/article/62b5d5ace81c405bb445c8cf7e9725a7
Autor:
Charles Gwellem Anchang, Cong Xu, Maria Gabriella Raimondo, Raja Atreya, Andreas Maier, Georg Schett, Vasily Zaburdaev, Simon Rauber, Andreas Ramming
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7506 (2021)
Immune-mediated inflammatory diseases (IMIDs), such as inflammatory bowel diseases and inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis), are marked by increasing worldwide incidence rates. Apart from irreversible damage of the
Externí odkaz:
https://doaj.org/article/ead5167c0e98474ba055c0bc2fd1f6b3
Autor:
Andreas Ramming, Simon Rauber, Hashem Mohammadian, Christian Schmidkonz, Armin Atzinger, Alina Soare, Christoph Treutlein, Samuel Kemble, Christopher Mahony, Manuel Geisthoff, Mario Angeli, Maria Raimondo, Cong Xu, Kai-Ting Yang, Le Lu, Hannah Labinsky, Mina Saad, Charles Gwellem, Eleni Kampylafka, Johannes Knitza, Jörg Distler, Megan Hanlon, Ursula Fearon, Douglas Veale, Frank Roemer, Tobias Bäuerle, Hans Maric, Simone Maschauer, Christopher Buckley, Adam Croft, Torsten Kuwert, Olaf Prante, Juan Cañete, Georg Schett
Fibroblasts are key orchestrators of inflammation. Little is known whether these cells change phenotype during resolution of inflammation. We adopted a method to visualise fibroblast activation during inflammation in humans in vivo, which is based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9318cbe23a870ef5b5e189cc306910b
https://doi.org/10.21203/rs.3.rs-2668533/v1
https://doi.org/10.21203/rs.3.rs-2668533/v1
Autor:
Simon Rauber, Hashem Mohammadian, Christian Schmidkonz, Armin Atzinger, Alina Soare, Simone Maschauer, Christoph Treutlein, Mario Angeli, Maria Gabriella Raimondo, Cong Xu, Kai-Ting Yang, Le Lu, Hannah Labinsky, Eleni Kampylafka, Johannes Knitza, Hans Maric, Jörg H.W. Distler, Tobias Bäuerle, Torsten Kuwert, Olaf Prante, Juan Cañete, Georg Schett, Andreas Ramming
Joint fibroblasts play an important role in the transition from joint inflammation to irreversible joint damage. There is no established clinical method to measure fibroblast activation during inflammation and their phenotypic dynamics upon therapy t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d78b362a094e12c867346f3afe40ca
https://doi.org/10.1101/2023.01.17.524425
https://doi.org/10.1101/2023.01.17.524425
Autor:
Lisa Kohl, Md Nur A Alam Siddique, Barbara Bodendorfer, Raffaela Berger, Annica Preikschat, Christoph Daniel, Martha Ölke, Elisabeth Liebler‐Tenorio, Jan Schulze‐Luehrmann, Michael Mauermeir, Kai‐Ting Yang, Inaya Hayek, Manuela Szperlinski, Jennifer Andrack, Ulrike Schleicher, Aline Bozec, Gerhard Krönke, Peter J Murray, Stefan Wirtz, Masahiro Yamamoto, Valentin Schatz, Jonathan Jantsch, Peter Oefner, Daniel Degrandi, Klaus Pfeffer, Katja Mertens‐Scholz, Simon Rauber, Christian Bogdan, Katja Dettmer, Anja Lührmann, Roland Lang
Infection with the intracellular bacterium Coxiella (C.) burnetii can cause chronic Q fever with severe complications and limited treatment options. Here, we identify the enzyme cis‐aconitate decarboxylase 1 (ACOD1 or IRG1) and its product itaconat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba32754d72f631e45f42cd20425dcf3f
https://epub.uni-regensburg.de/53429/
https://epub.uni-regensburg.de/53429/
Autor:
Olga G Cordeiro, Mélanie Chypre, Nathalie Brouard, Simon Rauber, Farouk Alloush, Monica Romera-Hernandez, Cécile Bénézech, Zhi Li, Anita Eckly, Mark C Coles, Antal Rot, Hideo Yagita, Catherine Léon, Burkhard Ludewig, Tom Cupedo, François Lanza, Christopher G Mueller
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151848 (2016)
Microenvironment and activation signals likely imprint heterogeneity in the lymphatic endothelial cell (LEC) population. Particularly LECs of secondary lymphoid organs are exposed to different cell types and immune stimuli. However, our understanding
Externí odkaz:
https://doaj.org/article/c21c765901a640338c1658927286699d
Autor:
Liliana F Mellor, Nuria Gago-Lopez, Latifa Bakiri, Felix N Schmidt, Björn Busse, Simon Rauber, Maria Jimenez, Diego Megías, Sergio Oterino-Sogo, Ricardo Sanchez-Prieto, Sergei Grivennikov, Xinzhu Pu, Julia Oxford, Andreas Ramming, Georg Schett, Erwin F Wagner
Publikováno v:
Annals of the rheumatic diseases.
[Objectives]: S100A9, an alarmin that can form calprotectin (CP) heterodimers with S100A8, is mainly produced by keratinocytes and innate immune cells. The contribution of keratinocyte-derived S100A9 to psoriasis (Ps) and psoriatic arthritis (PsA) wa
Autor:
Milena L Pachowsky, Maria Gabriella Raimondo, Cong Xu, Simon Rauber, Koray Tascilar, Hannah Labinsky, Mario Vogg, Mina Saad Aziz Saad, David Simon, Juergen Rech, Alina Soare, Lars Braeuer, Arnd Kleyer, Georg Schett, Andreas Ramming
Publikováno v:
Annals of the Rheumatic Diseases
ObjectivesTo establish a minimally invasive biopsy technique for the analysis of entheseal tissue in patients with psoriatic arthritis (PsA).MethodsHuman cadavers were used for establishing the technique to retrieve tissue from the lateral humeral ep