Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Simon, Milling"'
Autor:
Piaopiao Pan, Yilin Wang, Mukanthu H. Nyirenda, Zainulabedin Saiyed, Elnaz Karimian Azari, Amy Sunderman, Simon Milling, Margaret M. Harnett, Miguel Pineda
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Oral administration of harmless antigens can induce suppression of reactive immune responses, a process that capitalises on the ability of the gastrointestinal tract to tolerate exposure to food and commensal microbiome without triggering in
Externí odkaz:
https://doaj.org/article/640b84d26b4140398d5bb2b0ccf82607
Autor:
Reshmi Nair, Tamsin R. M. Lannagan, Rene Jackstadt, Anna Andrusaite, John Cole, Caitlin Boyne, Robert J. B. Nibbs, Owen J. Sansom, Simon Milling
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTColorectal cancer (CRC) is the third most prevalent cancer worldwide with a high mortality rate (20–30%), especially due to metastasis to adjacent organs. Clinical responses to chemotherapy, radiation, targeted and immunotherapies are limit
Externí odkaz:
https://doaj.org/article/990e4b206f444c4f9e950f6acf44d5d0
Autor:
Konstantinos Gkikas, Michael Logan, Ben Nichols, Umer Z. Ijaz, Clare M. Clark, Vaios Svolos, Lisa Gervais, Hazel Duncan, Vikki Garrick, Lee Curtis, Elaine Buchanan, Tracey Cardigan, Lawrence Armstrong, Caroline Delahunty, Diana M. Flynn, Andrew R. Barclay, Rachel Tayler, Simon Milling, Richard Hansen, Richard K. Russell, Konstantinos Gerasimidis
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background The anti-inflammatory effect of exclusive enteral nutrition on the gut of children with Crohn’s disease is rapidly lost after food reintroduction. This study assessed disease dietary triggers following successful treatment with
Externí odkaz:
https://doaj.org/article/cbe50ab996a24cd59fa8aacddecc3c19
Autor:
Mariola Kurowska-Stolarska, Stefano Alivernini, Emma Garcia Melchor, Aziza Elmesmari, Barbara Tolusso, Clare Tange, Luca Petricca, Derek S. Gilchrist, Gabriele Di Sante, Chantal Keijzer, Lynn Stewart, Clara Di Mario, Vicky Morrison, James M. Brewer, Duncan Porter, Simon Milling, Ronald D. Baxter, David McCarey, Elisa Gremese, Greg Lemke, Gianfranco Ferraccioli, Charles McSharry, Iain B. McInnes
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Axl is a TAM receptor that can inhibit Toll-like receptor (TLR) -induced pro-inflammatory production by dendritic cells (DC). Here the authors show that miR-34a targets Axl to control CD1c+ DC activity in mice, and that miR-34a-deficient mice are res
Externí odkaz:
https://doaj.org/article/82ffc64d997240fa87e18b12e513a829
Autor:
Heather E. Hulme, Lynsey M. Meikle, Hannah Wessel, Nicole Strittmatter, John Swales, Carolyn Thomson, Anna Nilsson, Robert J. B. Nibbs, Simon Milling, Per E. Andren, C. Logan Mackay, Alex Dexter, Josephine Bunch, Richard J. A. Goodwin, Richard Burchmore, Daniel M. Wall
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Salmonella Typhimurium causes a self-limiting gastroenteritis that may lead to systemic disease. Bacteria invade the small intestine, crossing the intestinal epithelium from where they are transported to the mesenteric lymph nodes (MLNs) wit
Externí odkaz:
https://doaj.org/article/3a24c8a8c4bd40bd88a9c66a0de21e92
Autor:
Madhura Castelino, Umer Z Ijaz, Mauro Tutino, Elizabeth MacDonald, George E. Fragoulis, Pauline Ho, Devesh Mewar, Gladston Chelliah, Andrew McBain, Catherine O’Neill, Stefan Siebert, Anne Barton, Simon Milling
ObjectivesThere is growing recognition that interactions between bacteria and the immune response may contribute to inflammation in psoriatic arthritis (PsA). To identify how the skin and stool microbiota may contribute to pathogenesis, we analysed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ded633c11bda510150ab24513786cf87
https://doi.org/10.1101/2023.05.18.23289979
https://doi.org/10.1101/2023.05.18.23289979
Autor:
Aleksandra Jatkowska, Bernadette White, Ben Nichols, Vaios Svolos, Konstantinos Gkikas, Richard Hansen, Richard K Russell, Daniel Gaya, Emily Brownson, John Paul Seenan, Simon Milling, Jonathan MacDonald, Konstantinos Gerasimidis
Publikováno v:
Journal of Crohn's and Colitis.
Background and Aims Treatment adherence is key to the efficacy of exclusive enteral nutrition [100% EN] in active Crohn’s disease [CD], but there are no biomarkers to objectively estimate this. We explored faecal parameters as biomarkers of complia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114c337947783074ab64af6188354bd0
https://doi.org/10.1093/ecco-jcc/jjad063
https://doi.org/10.1093/ecco-jcc/jjad063
Autor:
Heather Hulme, Lynsey M. Meikle, Nicole Strittmatter, John Swales, Gregory Hamm, Sheila L. Brown, Simon Milling, Andrew S. MacDonald, Richard J.A. Goodwin, Richard Burchmore, Daniel M. Wall
Publikováno v:
Hulme, H, Meikle, L M, Strittmatter, N, Swales, J, Hamm, G, Brown, S L, Milling, S, MacDonald, A S, Goodwin, R J A, Burchmore, R & Wall, D M 2022, ' Mapping the Influence of the Gut Microbiota on Small Molecules across the Microbiome Gut Brain Axis ', Journal of the American Society for Mass Spectrometry, vol. 33, no. 4, pp. 649-659 . https://doi.org/10.1021/jasms.1c00298
Microbes exert influence across the microbiome-gut-brain axis through neurotransmitter production, induction of host immunomodulators, or the release or induction of other microbial or host molecules. Here, we used mass spectrometry imaging (MSI), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33c87cf2db7287d9fee8689a2be61ee
https://doi.org/10.1021/jasms.1c00298
https://doi.org/10.1021/jasms.1c00298
Autor:
Michael Logan, Vikki Garrick, Caroline Delahunty, Lee Curtis, Umer Zeeshan Ijaz, Clare M. Clark, Lisa Gervais, Elaine Buchanan, Lawrence Armstrong, Konstantinos Gerasimidis, Hazel Duncan, Vaios Svolos, Andrew R. Barclay, Konstantinos Gkikas, Diana M. Flynn, Simon Milling, Richard Hansen, Tracey Cardigan, Richard K. Russell, Rachel Tayler, Ben Nichols
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Gastroenterology
BMC Gastroenterology
Background The anti-inflammatory effect of exclusive enteral nutrition on the gut of children with Crohn’s disease is rapidly lost after food reintroduction. This study assessed disease dietary triggers following successful treatment with exclusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4b170bd248cfb5d33fe3c95d81d154
https://doaj.org/article/cbe50ab996a24cd59fa8aacddecc3c19
https://doaj.org/article/cbe50ab996a24cd59fa8aacddecc3c19
Autor:
Mariola Kurowska-Stolarska, Chris M. Pacheco, Kim-Anh Lê Cao, Paul W. Angel, Vanta Jameson, Yidi Deng, Jennifer Gu, Christine A. Wells, Simon Milling, Andrew L. Laslett, Jarny Choi, Nadia Rajab, Matt Rutar
Publikováno v:
Stem Cell Reports
Summary The Stemformatics myeloid atlas is an integrated transcriptome atlas of human macrophages and dendritic cells that systematically compares freshly isolated tissue-resident, cultured, and pluripotent stem cell–derived myeloid cells. Three cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6640f3a36dcc2f783bb98fbe26cf87f5
https://doi.org/10.1016/j.stemcr.2021.04.010
https://doi.org/10.1016/j.stemcr.2021.04.010