Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Simon, M N"'
Autor:
Simon, M. N., Pascucci, I., Edwards, S., Feng, W., Gorti, U., Hollenbach, D., Rigliaco, E., Keane, J. T.
Using Keck/HIRES spectra {\Delta}v ~ 7 km/s, we analyze forbidden lines of [O I] 6300 {\AA}, [O I] 5577 {\AA} and [S II] 6731 {\AA} from 33 T Tauri stars covering a range of disk evolutionary stages. After removing a high velocity component (HVC) ass
Externí odkaz:
http://arxiv.org/abs/1608.06992
Autor:
Pascucci, I., Edwards, S., Heyer, M., Rigliaco, E., Hillenbrand, L., Gorti, U., Hollenbach, D., Simon, M. N.
We present a detailed analysis of narrow of NaI and KI absorption resonance lines toward nearly 40 T Tauri stars in Taurus with the goal of clarifying their origin. The NaI 5889.95 angstrom line is detected toward all but one source, while the weaker
Externí odkaz:
http://arxiv.org/abs/1510.02022
Autor:
Maloba M. M. Lobe, Simon M. N. Efange
Publikováno v:
Royal Society Open Science, Vol 7, Iss 1 (2020)
Both tetrahydroisoquinolines (THIQs) and oxindoles (OXs) display a broad range of biological activities including anti-cancer activity, and are therefore recognized as two privileged scaffolds in drug discovery. In the present study, 24 3′,4′-dih
Externí odkaz:
https://doaj.org/article/085cc046dde049edb57b95019718cf49
Autor:
Moses N. Ngemenya, Grace Ntube Abwenzoh, Hermia Nalova Ikome, Denis Zofou, Fidele Ntie-Kang, Simon M. N. Efange
Publikováno v:
BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background Emergence of resistance to artemisinins and some of their combinations in chemotherapy of clinical malaria has intensified the search for novel safe efficacious antimalarial molecules. Fourteen synthetic 1, 4-disubstituted piperid
Externí odkaz:
https://doaj.org/article/9a809e0d659b4c7e864ebec8443e83c9
Publikováno v:
Natural Products and Bioprospecting, Vol 7, Iss 3, Pp 235-247 (2017)
Abstract The antiparasitic activity and preliminary in vitro and in silico drug metabolism and pharmacokinetic (DMPK) assessment of six isomeric sesquiterpenes (1–6), isolated from the Cameroonian spice Scleria striatinux De Wild (Cyperaceae) is re
Externí odkaz:
https://doaj.org/article/ce3fcbe6464f41ac9679f0801be5e486
Akademický článek
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Autor:
Noella M. Efange, Maloba M. M. Lobe, Lauve R. T. Yamthe, Jeannette N. M. Pekam, Protus A. Tarkang, Lawrence Ayong, Simon M. N. Efange
Publikováno v:
Antimicrob Agents Chemother
Previous studies suggest that 3′,5′-dihydro-2′H-spiro[indoline-3,1′-isoquinolin]-2-ones (DSIIQs [spiroquindolones]) are multitarget antiplasmodial agents that combine the actions of spiroindolone and naphthylisoquinoline antimalarial agents.
Autor:
Cyril T. Namba-Nzanguim, Gemma Turon, Conrad V. Simoben, Ian Tietjen, Luis J. Montaner, Simon M. N. Efange, Miquel Duran-Frigola, Fidele Ntie-Kang
Publikováno v:
Frontiers in Drug Discovery. 2
Current antiviral drug discovery efforts face many challenges, including development of new drugs during an outbreak and coping with drug resistance due to rapidly accumulating viral mutations. Emerging artificial intelligence and machine learning (A
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1978 Feb 01. 75(2), 696-700.
Externí odkaz:
https://www.jstor.org/stable/67853