Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Simo V. Zhang"'
Autor:
Rachel Marty Pyke, Dattatreya Mellacheruvu, Steven Dea, Charles W. Abbott, Lee McDaniel, Devayani P. Bhave, Simo V. Zhang, Eric Levy, Gabor Bartha, John West, Michael P. Snyder, Richard O. Chen, Sean Michael Boyle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Human leukocyte antigen loss of heterozygosity (HLA LOH) is an important mechanism of immune escape in patients with cancer. Here the authors design and validate a machine learning algorithm with subclonal sensitivity for the identification of HLA LO
Externí odkaz:
https://doaj.org/article/3c5b35be291842048806866e0d0f7a0d
Autor:
Robert M. Waterhouse, Sergey Aganezov, Yoann Anselmetti, Jiyoung Lee, Livio Ruzzante, Maarten J. M. F. Reijnders, Romain Feron, Sèverine Bérard, Phillip George, Matthew W. Hahn, Paul I. Howell, Maryam Kamali, Sergey Koren, Daniel Lawson, Gareth Maslen, Ashley Peery, Adam M. Phillippy, Maria V. Sharakhova, Eric Tannier, Maria F. Unger, Simo V. Zhang, Max A. Alekseyev, Nora J. Besansky, Cedric Chauve, Scott J. Emrich, Igor V. Sharakhov
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-20 (2020)
Abstract Background New sequencing technologies have lowered financial barriers to whole genome sequencing, but resulting assemblies are often fragmented and far from ‘finished’. Updating multi-scaffold drafts to chromosome-level status can be ac
Externí odkaz:
https://doaj.org/article/0e880bd2992b417b9c80e8cec3c83014
Autor:
Rachel Marty Pyke, Dattatreya Mellacheruvu, Steven Dea, Charles W. Abbott, Simo V. Zhang, Nick A. Phillips, Jason Harris, Gabor Bartha, Sejal Desai, Rena McClory, John West, Michael P. Snyder, Richard Chen, Sean Michael Boyle
Publikováno v:
Mol Cell Proteomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9326cc388c109cbce3c86b95cd320d3d
https://europepmc.org/articles/PMC10114503/
https://europepmc.org/articles/PMC10114503/
Autor:
Richard Chen, Sekwon Jang, Michael P. Snyder, Rena McClory, Jason Harris, Gabor Bartha, Pamela Milani, Zeid M. Rusan, Rose Santiago, Mengyao Tan, Simo V. Zhang, Dattatreya Mellacheruvu, Fábio C.P. Navarro, Eric Levy, Lee D. McDaniel, Rachel Marty Pyke, Sean M. Boyle, Charles W. Abbott
Supplementary Data from Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3144b93620d2d48583a464aa8de5ad50
https://doi.org/10.1158/1078-0432.22480829
https://doi.org/10.1158/1078-0432.22480829
Autor:
Richard Chen, Sekwon Jang, Michael P. Snyder, Rena McClory, Jason Harris, Gabor Bartha, Pamela Milani, Zeid M. Rusan, Rose Santiago, Mengyao Tan, Simo V. Zhang, Dattatreya Mellacheruvu, Fábio C.P. Navarro, Eric Levy, Lee D. McDaniel, Rachel Marty Pyke, Sean M. Boyle, Charles W. Abbott
Supplementary Table from Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0086be9ebf1ffa1f151bb956bb5512fd
https://doi.org/10.1158/1078-0432.22480817.v1
https://doi.org/10.1158/1078-0432.22480817.v1
Autor:
Richard Chen, Sekwon Jang, Michael P. Snyder, Rena McClory, Jason Harris, Gabor Bartha, Pamela Milani, Zeid M. Rusan, Rose Santiago, Mengyao Tan, Simo V. Zhang, Dattatreya Mellacheruvu, Fábio C.P. Navarro, Eric Levy, Lee D. McDaniel, Rachel Marty Pyke, Sean M. Boyle, Charles W. Abbott
Purpose:While immune checkpoint blockade (ICB) has become a pillar of cancer treatment, biomarkers that consistently predict patient response remain elusive due to the complex mechanisms driving immune response to tumors. We hypothesized that a multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225a2c99cc8f1dfb0ef0bef13b61ae7c
https://doi.org/10.1158/1078-0432.c.6530534
https://doi.org/10.1158/1078-0432.c.6530534
Autor:
Richard Chen, Sekwon Jang, Michael P. Snyder, Rena McClory, Jason Harris, Gabor Bartha, Pamela Milani, Zeid M. Rusan, Rose Santiago, Mengyao Tan, Simo V. Zhang, Dattatreya Mellacheruvu, Fábio C.P. Navarro, Eric Levy, Lee D. McDaniel, Rachel Marty Pyke, Sean M. Boyle, Charles W. Abbott
Supplementary Figure from Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169244e7842d4c08e035f173b4a751a3
https://doi.org/10.1158/1078-0432.22480823
https://doi.org/10.1158/1078-0432.22480823
Autor:
Wazim Mohammed Ismail, Kymberleigh A Pagel, Vikas Pejaver, Simo V Zhang, Sofia Casasa, Matthew Mort, David N Cooper, Matthew W Hahn, Predrag Radivojac
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208901 (2018)
Recent genetic studies and whole-genome sequencing projects have greatly improved our understanding of human variation and clinically actionable genetic information. Smaller ethnic populations, however, remain underrepresented in both individual and
Externí odkaz:
https://doaj.org/article/b7f550463eb9492787f2c91e9feb7399
Autor:
Gabor Bartha, Jason B. Harris, Simo V. Zhang, Sean Michael Boyle, Michael Snyder, Rena McClory, Pamela Milani, Fabio C. P. Navarro, Rachel Marty Pyke, Eric Levy, Richard Chen, Zeid M. Rusan, Rose Santiago, Lee D. McDaniel, Mengyao Tan, Charles Abbott, Sekwon Jang, Dattatreya Mellacheruvu
Publikováno v:
Clinical Cancer Research. 27:4265-4276
Purpose: While immune checkpoint blockade (ICB) has become a pillar of cancer treatment, biomarkers that consistently predict patient response remain elusive due to the complex mechanisms driving immune response to tumors. We hypothesized that a mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da279827929c541b4969e02547f2b21b
https://doi.org/10.1158/1078-0432.ccr-20-4314
https://doi.org/10.1158/1078-0432.ccr-20-4314
Autor:
Simo V. Zhang, Gabor Bartha, Rachel Marty Pyke, Richard Chen, Sean Michael Boyle, Jason Harris, John A. West, Michael Snyder, Sejal Desai, Rena McClory, Charles Abbott, Dattatreya Mellacheruvu, Nick A. Phillips, Steven Dea
Publikováno v:
Mol Cell Proteomics
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Major histocompatibility complex (MHC)-bound peptides that originate from tumor-specific genetic alterations, known as neoantigens, are an important class of anticancer therapeutic targets. Accurately predicting peptide presentation by MHC complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d51c6de9d4672b239c32b76dd7d0721
https://doi.org/10.1016/j.mcpro.2023.100506
https://doi.org/10.1016/j.mcpro.2023.100506