Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Simo Ojanen"'
Autor:
Catalina Vasilescu, Mert Colpan, Tiina H. Ojala, Tuula Manninen, Aino Mutka, Kaisa Ylänen, Otto Rahkonen, Tuija Poutanen, Laura Martelius, Reena Kumari, Helena Hinterding, Virginia Brilhante, Simo Ojanen, Pekka Lappalainen, Juha Koskenvuo, Christopher J. Carroll, Velia M. Fowler, Carol C. Gregorio, Anu Suomalainen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Familial cardiomyopathy in pediatric stages is a poorly understood presentation of heart disease in children that is attributed to pathogenic mutations. Through exome sequencing, we report a homozygous variant in tropomodulin 1 (TMOD1; c.565
Externí odkaz:
https://doaj.org/article/17f82ec28ec14b21ac18fe950a134c51
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Kainate type glutamate receptors (KARs) are strongly expressed in GABAergic interneurons and have the capability of modulating their functions via ionotropic and G-protein coupled mechanisms. GABAergic interneurons are critical for generatio
Externí odkaz:
https://doaj.org/article/2b0e1d58157b415c817fb1a95e40c260
Autor:
Lingwei Huang, Ilari Riihioja, Petri Tanska, Simo Ojanen, Sanna Turunen, Heikki Kröger, Simo Saarakkala, Walter Herzog, Rami Korhonen, Mikko Finnilä
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100578- (2020)
Externí odkaz:
https://doaj.org/article/064c570a8a1d483699a5d0e8eafc2bbe
Autor:
Virva Hyttinen, Markus T. Sainio, Juho Aaltio, Henna Tyynismaa, Pentti J. Tienari, Emil Ylikallio, Simo Ojanen, Anders Paetau, Mika Kortelainen, Mari Auranen
Publikováno v:
Acta Neurologica Scandinavica. 145:63-72
Objectives Clinical diagnostics in adults with hereditary neurological diseases is complicated by clinical and genetic heterogeneity, as well as lifestyle effects. Here, we evaluate the effectiveness of exome sequencing and clinical costs in our diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1975ab4747b474dcee1823deb2737ce9
https://doi.org/10.1111/ane.13522
https://doi.org/10.1111/ane.13522
Autor:
Mikko A. J. Finnilä, Simo Ojanen, Rami K. Korhonen, Simo Saarakkala, Petri Tanska, Sanna Palosaari, Heikki Kröger, Walter Herzog, Lingwei Huang, Ilari Riihioja
Publikováno v:
Journal of Orthopaedic Research. 39:2556-2567
Concurrent osteoarthritic (OA) manifestations in bone and cartilage are poorly known. To shed light on this issue, this study aims to investigate changes in subchondral bone and articular cartilage at two time points after anterior cruciate ligament
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40525acfcd081407380997becfb99f9d
https://doi.org/10.1002/jor.25009
https://doi.org/10.1002/jor.25009
Autor:
Mohammadhossein Ebrahimi, Mikko A. J. Finnilä, Ali Mohammadi, Simo Ojanen, Heikki Kröger, Rami K. Korhonen, Antti Joukainen, Simo Saarakkala, Petri Tanska
Publikováno v:
Annals of Biomedical Engineering
Articular cartilage constituents (collagen, proteoglycans, fluid) are significantly altered during osteoarthritis (OA). A fibril-reinforced poroelastic (FRPE) material model can separate the contribution of each constituent on the mechanical response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8591c7f3834f5755363f841269fdb27
http://europepmc.org/articles/PMC8494710
http://europepmc.org/articles/PMC8494710
Autor:
Mohammadhossein Ebrahimi, Simo Ojanen, Ali Mohammadi, Mikko A. Finnilä, Antti Joukainen, Heikki Kröger, Simo Saarakkala, Rami K. Korhonen, Petri Tanska
Publikováno v:
Ann Biomed Eng
Articular cartilage constituents (collagen, proteoglycans, fluid) are significantly altered during osteoarthritis (OA). A fibril-reinforced poroelastic (FRPE) material model can separate the contribution of each constituent on the mechanical response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71712f409c0ebcf3453987195dbce9e0
https://europepmc.org/articles/PMC9172799/
https://europepmc.org/articles/PMC9172799/
Autor:
Simo Saarakkala, Walter Herzog, Lingwei Huang, Ilari Riihioja, Heikki Kröger, Sanna Turunen, Rami K. Korhonen, Simo Ojanen, Mikko A. J. Finnilä, Petri Tanska
Publikováno v:
Bone Reports, Vol 13, Iss, Pp 100578-(2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085b48bd2ebcf50351239647a6dfeee1
http://www.sciencedirect.com/science/article/pii/S2352187220303387
http://www.sciencedirect.com/science/article/pii/S2352187220303387
Autor:
Max Pohjanpelto, Päivi Lahermo, Erika Ignatius, Virginia Brilhante, Simo Ojanen, Tuula Lönnqvist, Christopher J. Carroll, Anu Suomalainen, Eino Palin, Pirjo Isohanni
Publikováno v:
Neurology: Genetics
ObjectiveTo characterize the genetic background of molecularly undefined childhood-onset ataxias in Finland.MethodsThis study examined a cohort of patients from 50 families with onset of an ataxia syndrome before the age of 5 years collected from a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7059710291f56102aca38a38599d00f
http://europepmc.org/articles/PMC7323479
http://europepmc.org/articles/PMC7323479
Autor:
Victor Casula, Mikko J. Nissi, Simo Ojanen, Miika T. Nieminen, Rami K. Korhonen, Mikko A. J. Finnilä, Simo Saarakkala, Walter Herzog, Abdul Wahed Kajabi
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research SocietyREFERENCES. 38(9)
In this study, the rabbit model with anterior cruciate ligament transection (ACLT) was used to investigate early degenerative changes in cartilage using multiparametric quantitative magnetic resonance imaging (qMRI). ACLT was surgically induced in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cd106d7023cb1c1d5b0aaaf10640d0
https://pubmed.ncbi.nlm.nih.gov/32129515
https://pubmed.ncbi.nlm.nih.gov/32129515