Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor-Targeted Therapy Drives Resistance in Breast Cancer.

Autor: Gemma C; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Lai CF; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Singh AK; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Belfiore A; Pathology Department, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.; School of Medicine, University of Milan, Milan, Italy., Portman N; Garvan Institute of Medical Research, Darlinghurst, Australia., Milioli HZ; Garvan Institute of Medical Research, Darlinghurst, Australia., Periyasamy M; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Raafat S; Division of Cancer and Stem Cells, Nottingham Breast Cancer Research Centre, University of Nottingham Biodiscovery Institute, University Park, Nottingham, United Kingdom.; Department of Histopathology, Nottingham University Hospital NHS Trust, City Hospital Campus, Nottingham, United Kingdom., Nicholls AJ; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Davies CM; Department of Surgery and Cancer, ECMC Imperial College, Imperial College London, Hammersmith Campus, London, United Kingdom., Patel NR; Department of Surgery and Cancer, ECMC Imperial College, Imperial College London, Hammersmith Campus, London, United Kingdom., Simmons GM; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Fan H; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Nguyen VTM; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Magnani L; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Rakha E; Division of Cancer and Stem Cells, Nottingham Breast Cancer Research Centre, University of Nottingham Biodiscovery Institute, University Park, Nottingham, United Kingdom.; Department of Histopathology, Nottingham University Hospital NHS Trust, City Hospital Campus, Nottingham, United Kingdom., Martin LA; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, United Kingdom., Lim E; Garvan Institute of Medical Research, Darlinghurst, Australia.; St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales Sydney, Sydney, Australia., Coombes RC; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Pruneri G; Pathology Department, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.; School of Medicine, University of Milan, Milan, Italy., Buluwela L; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom., Ali S; Department of Surgery and Cancer, Imperial College London, Hammersmith Campus, London, United Kingdom.

Publikováno v: Cancer research [Cancer Res] 2024 Dec 16; Vol. 84 (24), pp. 4283-4297.

Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer.

Autor: Harrod A; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK.; Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK., Lai CF; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK., Goldsbrough I; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK., Simmons GM; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK., Oppermans N; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK., Santos DB; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK., Győrffy B; Semmelweis University Department of Bioinformatics, H-1094 Budapest, Hungary and TTK Cancer Biomarker Research Group, H-1117, Budapest, Hungary., Allsopp RC; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, LE2 7LX, UK., Toghill BJ; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, LE2 7LX, UK., Balachandran K; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK., Lawson M; Early Oncology R&D, AstraZeneca, Biomedical Campus, 1 Francis Crick Ave, Cambridge, CB2 0AA, UK., Morrow CJ; Early Oncology R&D, AstraZeneca, Biomedical Campus, 1 Francis Crick Ave, Cambridge, CB2 0AA, UK., Surakala M; Early Oncology R&D, AstraZeneca, Biomedical Campus, 1 Francis Crick Ave, Cambridge, CB2 0AA, UK., Carnevalli LS; Early Oncology R&D, AstraZeneca, Biomedical Campus, 1 Francis Crick Ave, Cambridge, CB2 0AA, UK., Zhang P; Early Oncology R&D, AstraZeneca, Biomedical Campus, 1 Francis Crick Ave, Cambridge, CB2 0AA, UK., Guttery DS; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, LE2 7LX, UK., Shaw JA; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, LE2 7LX, UK., Coombes RC; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK., Buluwela L; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK. l.buluwela@imperial.ac.uk., Ali S; Department of Surgery & Cancer, Imperial College London, London, W12 0NN, UK. simak.ali@imperial.ac.uk.

Publikováno v: Oncogene [Oncogene] 2022 Oct; Vol. 41 (44), pp. 4905-4915. Date of Electronic Publication: 2022 Oct 05.

Treatment of Calcified Cephalohematoma

Autor: Simmons Gm, Anderson Rp, Sydney S. Schochet, Howard H. Kaufman, Hochberg J

Publikováno v: Neurosurgery. 32:1037-1040

This is a case report concerning the surgical treatment of a calcified cephalohematoma, which was possibly caused by an intrauterine fetal monitor. This is the first report of this particular entity as a complication of an intrauterine fetal monitor.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18b3bd44bf8b12745a64b3f31b230be
https://doi.org/10.1227/00006123-199306000-00029

Early First-trimester Diagnosis of Partial Hydatidiform Mole with Coexistent Live Fetus in Twin Pregnancy.

Autor: Toshiyuki Hata^1,2 toshi28@med.kagawa-u.ac.jp, Aya Itoh¹, Riko Takayoshi^1,2, Takahito Miyake^1,2, Mika Sugihara^1,3, Koichiro Shimoya³, Hirotake Nishimura⁴, Kazuhiko Ino⁵

Publikováno v: Donald School Journal of Ultrasound in Obstetrics & Gynecology. Oct-Dec2023, Vol. 17 Issue 4, p369-372. 4p.

Bacterial Communities in Cryoconite Holes of the Adjacent Glaciers on the Tibetan Plateau.

Autor: Wang, Wenqiang^1,2 (AUTHOR), Liu, Yongqin^2,3,4 (AUTHOR), Liu, Keshao^3,4 (AUTHOR), Yan, Qi^1,2 (AUTHOR), Ji, Mukang² (AUTHOR), Wang, Feng³ (AUTHOR), Zhang, Zhihao³ (AUTHOR)

Publikováno v: Geomicrobiology Journal. Jul2023, Vol. 40 Issue 7, p632-639. 8p.