Genomic surveillance reveals dynamic shifts in the connectivity of COVID-19 epidemics.

Autor: Matteson NL; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA. Electronic address: natem@scripps.edu., Hassler GW; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Kurzban E; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Schwab MA; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Perkins SA; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Gangavarapu K; Department of Biomathematics, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA, USA; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Levy JI; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Parker E; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Pride D; Department of Pathology, University of California, San Diego, La Jolla, CA, USA; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Hakim A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA, USA; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., De Hoff P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA, USA; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Cheung W; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA, USA; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Castro-Martinez A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA, USA; Sanford Consortium of Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA., Rivera A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Veder A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Rivera A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Wauer C; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Holmes J; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Wilson J; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Ngo SN; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Plascencia A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Lawrence ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Smoot EW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Eisner ER; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Tsai R; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Chacón M; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Baer NA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Seaver P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Salido RA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Aigner S; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Ngo TT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Barber T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Ostrander T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Fielding-Miller R; Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA; Division of Infectious Disease and Global Public Health, University of California, San Diego, La Jolla, CA, USA., Simmons EH; Academic Affairs, University of California, San Diego, La Jolla, CA, USA., Zazueta OE; Department of Epidemiology, Secretaria de Salud de Baja California, Tijuana, Baja California, Mexico., Serafin-Higuera I; Centro de Diagnostico COVID-19 UABC, Tijuana, Baja California, Mexico., Sanchez-Alavez M; Centro de Diagnostico COVID-19 UABC, Tijuana, Baja California, Mexico; Department of Molecular Medicine, Scripps Research, La Jolla, CA, USA., Moreno-Camacho JL; Clinical Laboratory Department, Salud Digna, A.C, Tijuana, Baja California, Mexico., García-Gil A; Clinical Laboratory Department, Salud Digna, A.C, Tijuana, Baja California, Mexico., Murphy Schafer AR; County of San Diego Health and Human Services Agency, San Diego, CA, USA., McDonald E; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Corrigan J; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Malone JD; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Stous S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Shah S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Moshiri N; Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA, USA., Weiss A; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Anderson C; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Aceves CM; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Spencer EG; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Hufbauer EC; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Lee JJ; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., King AJ; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Ramesh KS; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Nguyen KN; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Saucedo K; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Robles-Sikisaka R; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Fisch KM; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA, USA; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Gonias SL; Department of Pathology, University of California, San Diego, La Jolla, CA, USA., Birmingham A; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., McDonald D; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Karthikeyan S; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Martin NK; Division of Infectious Disease and Global Public Health, University of California, San Diego, La Jolla, CA, USA., Schooley RT; Division of Infectious Disease and Global Public Health, University of California, San Diego, La Jolla, CA, USA., Negrete AJ; Facultad de Ciencias de la Salud Universidad Autonoma de Baja California Valle de Las Palmas, Tijuana, Baja California, Mexico., Reyna HJ; Facultad de Ciencias de la Salud Universidad Autonoma de Baja California Valle de Las Palmas, Tijuana, Baja California, Mexico., Chavez JR; Facultad de Ciencias de la Salud Universidad Autonoma de Baja California Valle de Las Palmas, Tijuana, Baja California, Mexico., Garcia ML; Facultad de Ciencias de la Salud Universidad Autonoma de Baja California Valle de Las Palmas, Tijuana, Baja California, Mexico., Cornejo-Bravo JM; Facultad de Ciencias Quimicas e Ingenieria, Universidad Autonoma de Baja California, Tijuana, Baja California, Mexico., Becker D; Helix, San Mateo, CA, USA., Isaksson M; Helix, San Mateo, CA, USA., Washington NL; Helix, San Mateo, CA, USA., Lee W; Helix, San Mateo, CA, USA., Garfein RS; Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA., Luna-Ruiz Esparza MA; Innovation and Research Department, Salud Digna, A.C, Tijuana, Baja California, Mexico., Alcántar-Fernández J; Innovation and Research Department, Salud Digna, A.C, Tijuana, Baja California, Mexico., Henson B; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Jepsen K; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Olivares-Flores B; Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE), Ciudad de México, CDMX, Mexico., Barrera-Badillo G; Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE), Ciudad de México, CDMX, Mexico., Lopez-Martínez I; Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE), Ciudad de México, CDMX, Mexico., Ramírez-González JE; Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE), Ciudad de México, CDMX, Mexico., Flores-León R; Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE), Ciudad de México, CDMX, Mexico., Kingsmore SF; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Sanders A; Return to Learn, University of California, San Diego, La Jolla, CA, USA., Pradenas A; Return to Learn, University of California, San Diego, La Jolla, CA, USA., White B; Return to Learn, University of California, San Diego, La Jolla, CA, USA., Matthews G; Return to Learn, University of California, San Diego, La Jolla, CA, USA., Hale M; Return to Learn, University of California, San Diego, La Jolla, CA, USA., McLawhon RW; Return to Learn, University of California, San Diego, La Jolla, CA, USA., Reed SL; Return to Learn, University of California, San Diego, La Jolla, CA, USA., Winbush T; Return to Learn, University of California, San Diego, La Jolla, CA, USA., McHardy IH; Scripps Health, La Jolla, San Diego, CA, USA., Fielding RA; Scripps Health, La Jolla, San Diego, CA, USA., Nicholson L; Scripps Health, La Jolla, San Diego, CA, USA., Quigley MM; Scripps Health, La Jolla, San Diego, CA, USA., Harding A; Sharp Healthcare, San Diego, CA, USA., Mendoza A; Sharp Healthcare, San Diego, CA, USA., Bakhtar O; Sharp Healthcare, San Diego, CA, USA., Browne SH; Division of Infectious Disease and Global Public Health, University of California, San Diego, La Jolla, CA, USA; Specialist in Global Health, Encinitas, CA, USA., Olivas Flores J; Facultad de Ciencias Quimicas e Ingenieria, Universidad Autonoma de Baja California, Tijuana, Baja California, Mexico; University of HealthMx, Tijuana, Baja California, Mexico., Rincon Rodríguez DG; University of HealthMx, Tijuana, Baja California, Mexico; Facultad de Medicina, Universidad Xochicalco, Tijuana, Baja California, Mexico., Gonzalez Ibarra M; University of HealthMx, Tijuana, Baja California, Mexico; Facultad de Medicina, Universidad Xochicalco, Tijuana, Baja California, Mexico., Robles Ibarra LC; University of HealthMx, Tijuana, Baja California, Mexico; Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Tijuana, Baja California, Mexico., Arellano Vera BJ; University of HealthMx, Tijuana, Baja California, Mexico; Instituto Mexicano del Seguro Social, Tijuana, Baja California, Mexico., Gonzalez Garcia J; University of HealthMx, Tijuana, Baja California, Mexico; SIMNSA, Tijuana, Baja California, Mexico., Harvey-Vera A; University of California, San Diego, La Jolla, CA, USA., Knight R; Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA, USA; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Laurent LC; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, CA, USA; Sanford Consortium of Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA., Yeo GW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Sanford Consortium of Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Wertheim JO; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Ji X; Department of Mathematics, School of Science and Engineering, Tulane University, New Orleans, LA, USA., Worobey M; Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ, USA., Suchard MA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Andersen KG; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA. Electronic address: andersen@scripps.edu., Campos-Romero A; Innovation and Research Department, Salud Digna, A.C, Tijuana, Baja California, Mexico., Wohl S; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA., Zeller M; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA. Electronic address: zellerm@scripps.edu.

Publikováno v: Cell [Cell] 2023 Dec 21; Vol. 186 (26), pp. 5690-5704.e20. Date of Electronic Publication: 2023 Dec 14.

Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission.

Autor: Karthikeyan S; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Levy JI; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., De Hoff P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Humphrey G; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Birmingham A; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Jepsen K; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA., Farmer S; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tubb HM; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Valles T; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tribelhorn CE; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tsai R; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Aigner S; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Sathe S; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Moshiri N; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA., Henson B; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA., Mark AM; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Hakim A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Baer NA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Barber T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Belda-Ferre P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Chacón M; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Cheung W; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Cresini ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Eisner ER; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Lastrella AL; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Lawrence ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Marotz CA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Ngo TT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Ostrander T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Plascencia A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Salido RA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Seaver P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Smoot EW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., McDonald D; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Neuhard RM; Operational Strategic Initiatives, University of California San Diego, La Jolla, CA, USA.; Return to Learn, University of California San Diego, La Jolla, CA, USA., Scioscia AL; Student Health and Well-Being, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA., Satterlund AM; Student Affairs, University of California San Diego, La Jolla, CA, USA., Simmons EH; Academic Affairs, University of California San Diego, La Jolla, CA, USA., Abelman DB; Return to Learn, University of California San Diego, La Jolla, CA, USA., Brenner D; Return to Learn, University of California San Diego, La Jolla, CA, USA., Bruner JC; Return to Learn, University of California San Diego, La Jolla, CA, USA., Buckley A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ellison M; Return to Learn, University of California San Diego, La Jolla, CA, USA., Gattas J; Return to Learn, University of California San Diego, La Jolla, CA, USA., Gonias SL; Department of Pathology, University of California San Diego, La Jolla, CA, USA., Hale M; Return to Learn, University of California San Diego, La Jolla, CA, USA., Hawkins F; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ikeda L; Return to Learn, University of California San Diego, La Jolla, CA, USA., Jhaveri H; Return to Learn, University of California San Diego, La Jolla, CA, USA., Johnson T; Return to Learn, University of California San Diego, La Jolla, CA, USA., Kellen V; Return to Learn, University of California San Diego, La Jolla, CA, USA., Kremer B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Matthews G; Return to Learn, University of California San Diego, La Jolla, CA, USA., McLawhon RW; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ouillet P; Return to Learn, University of California San Diego, La Jolla, CA, USA., Park D; Return to Learn, University of California San Diego, La Jolla, CA, USA., Pradenas A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Reed S; Return to Learn, University of California San Diego, La Jolla, CA, USA., Riggs L; Return to Learn, University of California San Diego, La Jolla, CA, USA., Sanders A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Sollenberger B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Song A; Operational Strategic Initiatives, University of California San Diego, La Jolla, CA, USA.; Return to Learn, University of California San Diego, La Jolla, CA, USA., White B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Winbush T; Return to Learn, University of California San Diego, La Jolla, CA, USA., Aceves CM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Anderson C; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Gangavarapu K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Hufbauer E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Kurzban E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Lee J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Matteson NL; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Parker E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Perkins SA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Ramesh KS; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Robles-Sikisaka R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Schwab MA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Spencer E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Wohl S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Nicholson L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Mchardy IH; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Dimmock DP; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Hobbs CA; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Bakhtar O; Sharp Healthcare, San Diego, CA, USA., Harding A; Sharp Healthcare, San Diego, CA, USA., Mendoza A; Sharp Healthcare, San Diego, CA, USA., Bolze A; Helix, San Mateo, CA, USA., Becker D; Helix, San Mateo, CA, USA., Cirulli ET; Helix, San Mateo, CA, USA., Isaksson M; Helix, San Mateo, CA, USA., Barrett KMS; Helix, San Mateo, CA, USA., Washington NL; Helix, San Mateo, CA, USA., Malone JD; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Schafer AM; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Gurfield N; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Stous S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Fielding-Miller R; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Garfein RS; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Gaines T; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Anderson C; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Martin NK; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Schooley R; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Austin B; Sharp Healthcare, San Diego, CA, USA., MacCannell DR; Office of Advanced Molecular Detection, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kingsmore SF; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Lee W; Helix, San Mateo, CA, USA., Shah S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., McDonald E; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Yu AT; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Zeller M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Fisch KM; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA., Longhurst C; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Biomedical Informatics, University of California, San Diego, La Jolla, California, USA., Maysent P; Office of the UC San Diego Health CEO, University of California, San Diego., Pride D; Departments of Pathology and Medicine, University of California, San Diego, La Jolla, CA., Khosla PK; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA., Laurent LC; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA., Yeo GW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA., Andersen KG; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Knight R; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2022 Apr 04. Date of Electronic Publication: 2022 Apr 04.

Distinguishing flavor nonuniversal colorons from Z′ bosons at the LHC

Autor: Chivukula, RS, Ittisamai, P, Simmons, EH

Publikováno v: Physical Review D, vol 91, iss 5
Physical Review D-Particles, Fields, Gravitation and Cosmology, vol 91, iss 5

Electrically neutral massive color-singlet and color-octet vector bosons, which are often predicted in theories beyond the Standard Model, have the potential to be discovered as dijet resonances at the LHC. A color-singlet resonance that has leptopho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b5d5208c9dc7fa1600415e28d36df4ce
https://escholarship.org/uc/item/9zp3z06p

Four-site Higgsless model with wave function mixing

Autor: Chivukula, RS, Simmons, EH

Publikováno v: Physical Review D, vol 78, iss 7
Physical Review D-Particles, Fields, Gravitation and Cosmology, vol 78, iss 7

Motivated by models of holographic technicolor, we discuss a four-site deconstructed Higgsless model with nontrivial wave function mixing. We compute the spectrum of the model, the electroweak triple gauge-boson vertices, and, for brane-localized fer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2735e7e41b157dccf8fd6dacfd10561f
https://escholarship.org/uc/item/88c0b3wp

Top Theories

Autor: Simmons, EH

As the most recently discovered and heaviest quark, the top presents us with theoretical challenges. How are we to understand its properties within the larger effort to explain the origins of electroweak and flavor symmetry breaking ? This talk discu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ce808e55be6562d84e3962fa7937682f
https://escholarship.org/uc/item/11k7q2g3