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of 2
pro vyhledávání: '"Simmler, Patrik T"'
Autor:
Simmler, Patrik T., Mengis, Tamara, Lehmann, Kjong-Van, Kahles, André, Thomas, Tinu, Rätsch, Gunnar, Stoffel, Markus, Schwank, Gerald
Publikováno v:
bioRxiv
The splicing factor SF3B1 is recurrently mutated in various tumors, including pancreatic ductal adenocarcinoma (PDAC). The impact of the hotspot mutation SF3B1K700E on the PDAC pathogenesis, however, remains elusive. Here, we demonstrate that Sf3b1K7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dcbc9fb31ec77dcf8a05974f95a4d28
https://hdl.handle.net/20.500.11850/595164
https://hdl.handle.net/20.500.11850/595164
Autor:
Simmler, Patrik T, Cortijo, Cédric, Koch, Lisa M, Galliker, Patricia, Angori, Silvia, Bolck, Hella A, Mueller, Christina, Vukolic, Ana, Mirtschink, Peter, Christinat, Yann, Davidson, Natalie R, Lehmann, Kjong-Van, Pellegrini, Giovanni, Pauli, Chantal, Lenggenhager, Daniela, Guccini, Ilaria, Ringel, Till, Hirt, Christian, Rätsch, Gunnar, Moch, Holger, Stoffel, Markus, Schwank, Gerald
Publikováno v:
bioRxiv
Heterozygous mutations in the splicing factor SF3B1 are frequently occurring in various cancers and drive tumor progression through the activation of cryptic splice sites in multiple genes. Recent studies moreover demonstrate a positive correlation b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c6a55e7c0eea933680f268123df54d
https://hdl.handle.net/20.500.11850/465539
https://hdl.handle.net/20.500.11850/465539