Výsledky vyhledávání - "Simin N Meydani"

Akademický článek

Vital role for primary healthcare providers: urgent need to educate the community about daily nutritional self-care to support immune function and maintain health

Autor: Philip C Calder, Anna Bach-Faig, Teresa Bevacqua, Chrystopherson Gengyny Caballero Lopez, Zheng-Yu Chen, Daragh Connolly, Wan Lee Koay, Simin N Meydani, Ari-Sentug Pinar, Durval Ribas-Filho, Adeline Pierre

Publikováno v: BMJ Nutrition, Prevention & Health, Vol 6, Iss 2 (2023)

The importance of self-care to improve health and social well-being is well recognised. Nevertheless, there remains a need to encourage people to better understand how their body works, and how to keep it healthy. Because of its important role, part

Externí odkaz: https://doaj.org/article/eaca454e12e1411ba15c0712026b05e8

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Akademický článek

Safe and effective delivery of supplemental iron to healthy older adults: The double-blind, randomized, placebo-controlled trial protocol of the Safe Iron Study [version 2; peer review: 2 approved, 1 approved with reservations]

Autor: Erin D. Lewis, Dayong Wu, Joel B. Mason, Athar H. Chishti, John M. Leong, Kathryn Barger, Simin N. Meydani, Gerald F. Combs

Publikováno v: Gates Open Research, Vol 3 (2021)

The forms of iron currently available to correct iron deficiency have adverse effects, including infectious diarrhea, increased susceptibility to malaria, inflammation and detrimental changes to the gut microbiome. These adverse effects limit their u

Externí odkaz: https://doaj.org/article/548cdf5758c2410b98bb478c30947b23

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Nutrition, Immunosenescence, and Infectious Disease: An Overview of the Scientific Evidence on Micronutrients and on Modulation of the Gut Microbiota

Autor: Philip C Calder, Edwin Frank Ortega, Simin N Meydani, Yuriko Adkins, Charles B Stephensen, Brice Thompson, Heather Zwickey

Publikováno v: Advances in nutrition (Bethesda, Md.), vol 13, iss 5

The immune system is key to host defense against pathogenic organisms. Aging is associated with changes in the immune system, with a decline in protective components (immunosenescence), increasing susceptibility to infectious disease, and a chronic e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5d7bbaf1d443617cb37a8d7a96a4d2
https://escholarship.org/uc/item/8zh4v8km

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Akademický článek

The Alpha-Tocopherol Form of Vitamin E Boosts Elastase Activity of Human PMNs and Their Ability to Kill Streptococcus pneumoniae

Autor: Elsa N. Bou Ghanem, James N. Lee, Basma H. Joma, Simin N. Meydani, John M. Leong, Alexander Panda

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)

Despite the availability of vaccines, Streptococcus pneumoniae remains a leading cause of life-threatening infections, such as pneumonia, bacteremia and meningitis. Polymorphonuclear leukocytes (PMNs) are a key determinant of disease course, because

Externí odkaz: https://doaj.org/article/25c6b241813840b68323d33775b96f53

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Perspective: Role of Micronutrients and Omega-3 Long-Chain Polyunsaturated Fatty Acids for Immune Outcomes of Relevance to Infections in Older Adults-A Narrative Review and Call for Action

Autor: Manfred Eggersdorfer, Mette M Berger, Philip C Calder, Adrian F Gombart, Emily Ho, Alessandro Laviano, Simin N Meydani

Publikováno v: Advances in nutrition (Bethesda, Md.). 13(5)

The immune system is weakened by advancing age, often referred to as immunosenescence, increasing the vulnerability to, and frequently the severity of, infectious diseases in older people. This has become very apparent in the current coronavirus dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0640715206c0394fe940f31639a08b6d
https://pubmed.ncbi.nlm.nih.gov/35587877

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Akademický článek

Effect of a therapeutic lifestyle change diet on immune functions of moderately hypercholesterolemic humans

Autor: Sung Nim Han, Lynette S. Leka, Alice H. Lichtenstein, Lynne M. Ausman, Simin N. Meydani

Publikováno v: Journal of Lipid Research, Vol 44, Iss 12, Pp 2304-2310 (2003)

Hypercholesterolemia is a risk factor for coronary heart disease (CHD) and also could contribute to impaired immune response. The National Cholesterol Education Program Expert Panel recommends a therapeutic lifestyle change (TLC) diet to reduce the r

Externí odkaz: https://doaj.org/article/7ac40efb38b64ec7861f6b769e800d55

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Macrophage LC3-associated phagocytosis is an immune defense against

Autor: Megumi, Inomata, Shuying, Xu, Pallavi, Chandra, Simin N, Meydani, Genzou, Takemura, Jennifer A, Philips, John M, Leong

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance The elderly exhibit susceptibility to many infectious agents, including S. pneumoniae. A robust acute inflammatory response to S. pneumoniae is associated with severe disease. S. pneumoniae triggers canonical autophagy in nonprofessional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25b0a45bce0a4618899905e867585a44
https://pubmed.ncbi.nlm.nih.gov/33376222

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Patterns of antimicrobial use for respiratory tract infections in older residents of long-term care facilities

Autor: Paschalis, Vergidis, Davidson H, Hamer, Simin N, Meydani, Gerard E, Dallal, Tamar F, Barlam

Publikováno v: Journal of the American Geriatrics Society. 59(6)

To describe patterns of antimicrobial use for respiratory tract infections (RTIs) in older residents of long-term care facilities (LTCFs).Data from a prospective, randomized, controlled study of the effect of vitamin E supplementation on RTIs conduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2cae75442b5652c8ab2f9c84106f1344
https://pubmed.ncbi.nlm.nih.gov/21539527

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