Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Simin Abrishami"'
Autor:
Ziru Li, Devika P. Bagchi, Junxiong Zhu, Emily Bowers, Hui Yu, Julie Hardij, Hiroyuki Mori, Katrina Granger, Jon Skjaerlund, Gurjit Mandair, Simin Abrishami, Kanakadurga Singer, Kurt D. Hankenson, Clifford J. Rosen, Ormond A. MacDougald
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2022)
BM adipocytes (BMAd) are a unique cell population derived from BM mesenchymal progenitors and marrow adipogenic lineage precursors. Although they have long been considered to be a space filler within bone cavities, recent studies have revealed import
Externí odkaz:
https://doaj.org/article/e9976e8be4f24f9c9922df962dd23f60
Autor:
Ziru Li, Emily Bowers, Junxiong Zhu, Hui Yu, Julie Hardij, Devika P Bagchi, Hiroyuki Mori, Kenneth T Lewis, Katrina Granger, Rebecca L Schill, Steven M Romanelli, Simin Abrishami, Kurt D Hankenson, Kanakadurga Singer, Clifford J Rosen, Ormond A MacDougald
Publikováno v:
eLife, Vol 11 (2022)
To investigate roles for bone marrow adipocyte (BMAd) lipolysis in bone homeostasis, we created a BMAd-specific Cre mouse model in which we knocked out adipose triglyceride lipase (ATGL, Pnpla2 gene). BMAd-Pnpla2-/- mice have impaired BMAd lipolysis,
Externí odkaz:
https://doaj.org/article/bdfc9a8605954c97a63a34c772b7a140
Autor:
Mita Varghese, Jeremy Clemente, Arianna Lerner, Simin Abrishami, Mohammed Islam, Perla Subbaiah, Kanakadurga Singer
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Obesity is associated with systemic inflammation and immune cell recruitment to metabolic tissues. Sex differences have been observed where male mice challenged with high fat diet (HFD) exhibit greater adipose tissue inflammation than females demonst
Externí odkaz:
https://doaj.org/article/6df4a0e44b1641e89410d0c64acb5e19
Autor:
Cameron Griffin, Chelsea R. Hutch, Simin Abrishami, Daria Stelmak, Leila Eter, Ziru Li, Eric Chang, Devyani Agarwal, Brian Zamarron, Mita Varghese, Perla Subbaiah, Ormond A. MacDougald, Darleen A. Sandoval, Kanakadurga Singer
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-16 (2019)
Abstract Background Weight loss by surgery or lifestyle changes is strongly recommended for obese individuals to improve metabolic health, but the underlying impairments that persist from a history of obesity remain unclear. Recent investigations dem
Externí odkaz:
https://doaj.org/article/0eb8f96c2ae3414c8d70662c2c7f319d
Autor:
Cecilia Gállego-Suárez, Ayse Bulan, Emily Hirschfeld, Phillip Wachowiak, Simin Abrishami, Cameron Griffin, Julie Sturza, Abigail Tzau, Taryn Hayes, Susan J. Woolford, Carey N. Lumeng, Joyce M. Lee, Kanakadurga Singer
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Objective: We aimed to examine if myeloid leukocyte profiles are associated with metabolic impairment in children and adolescents with obesity, and if sex, age, or race influence this relationship.Methods: 282 children ages 8–17 were evaluated. Pre
Externí odkaz:
https://doaj.org/article/b7d01ac797954a4e91e3f8b19176f888
Autor:
Simin Abrishami, Mita Varghese, Jason S Villano, Mohammed R Islam, Kanakadurga Singer, Kimberly A Schultz
Publikováno v:
J Am Assoc Lab Anim Sci
Understanding how differences in animal husbandry practices affect the reproducibility of research results is critical. We sought to understand how different beddings might influence dietary obesity studies. We compared the effects of paper and cornc
Autor:
Ziru Li, Emily Bowers, Junxiong Zhu, Hui Yu, Julie Hardij, Devika P Bagchi, Hiroyuki Mori, Kenneth T Lewis, Katrina Granger, Rebecca L Schill, Steven M Romanelli, Simin Abrishami, Kurt D Hankenson, Kanakadurga Singer, Clifford J Rosen, Ormond A MacDougald
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4353134fa1ffb498c0b62f5183dbeea
https://doi.org/10.7554/elife.78496.sa2
https://doi.org/10.7554/elife.78496.sa2
Publikováno v:
Diabetes. 71
Obesity-induced inflammation is a risk factor for metabolic impairment leading to diabetes and cardiovascular disease. We, and others, have shown that sex differences exist in adipose tissue (AT) and myeloid inflammatory responses to high-fat diet (H
Autor:
Mita Varghese, Kaitlin McKernan, Simin Abrishami, Leila Eter, Kanakadurga Singer, Cameron Griffin
Publikováno v:
Aging (Albany NY)
Aging, like obesity, is associated with metabolic and inflammatory alterations within adipose tissue in older individuals. Younger females are protected from adipose inflammation, but older post-menopausal females exhibit exaggerated visceral adiposi
Autor:
Mita Varghese, Jeremy Clemente, Arianna Lerner, Simin Abrishami, Mohammed Islam, Perla Subbaiah, Kanakadurga Singer
Publikováno v:
Frontiers in endocrinology. 13
Obesity is associated with systemic inflammation and immune cell recruitment to metabolic tissues. Sex differences have been observed where male mice challenged with high fat diet (HFD) exhibit greater adipose tissue inflammation than females demonst