Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Simian/Human immunodeficiency virus"'
Autor:
Yanxin Gai, Nan Gao, Zhaoyang Mou, Chumeng Yang, Libian Wang, Wanshan Ji, Tiejun Gu, Bin Yu, Chu Wang, Xianghui Yu, Feng Gao
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7200 (2024)
Viral infection generally induces polyclonal neutralizing antibody responses. However, how many lineages of antibody responses can fully represent the neutralization activities in sera has not been well studied. Using the newly designed stable HIV-1
Externí odkaz:
https://doaj.org/article/30049a2fd863481e87e342547e918762
Akademický článek
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Autor:
Nan Gao, Yanxin Gai, Lina Meng, Chu Wang, Wei Wang, Xiaojun Li, Tiejun Gu, Mark K. Louder, Nicole A. Doria‐Rose, Kevin Wiehe, Alexandra F. Nazzari, Adam S. Olia, Jason Gorman, Reda Rawi, Wenmin Wu, Clayton Smith, Htet Khant, Natalia de Val, Bin Yu, Junhong Luo, Haitao Niu, Yaroslav Tsybovsky, Huaxin Liao, Thomas B. Kepler, Peter D. Kwong, John R. Mascola, Chuan Qin, Tongqing Zhou, Xianghui Yu, Feng Gao
Publikováno v:
Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)
Abstract Understanding maturation pathways of broadly neutralizing antibodies (bnAbs) against HIV‐1 can be highly informative for HIV‐1 vaccine development. A lineage of J038 bnAbs is now obtained from a long‐term SHIV‐infected macaque. J038
Externí odkaz:
https://doaj.org/article/bb2780d69c034667a7617667bf5974ca
Publikováno v:
Pathogens and Immunity, Vol 1, Iss 1, Pp 41-67 (2016)
Since the discovery of the first inhibitors of HIV replication, drug resistance has been a major problem in HIV therapy, due, in part, to the high mutation rate of HIV. Therefore, the development of a predictive animal model is important to identify
Externí odkaz:
https://doaj.org/article/b95939978be84d029904bc65de4650ff
Autor:
Nan Gao, Yanxin Gai, Lina Meng, Chu Wang, Xin Zhang, Wei Wang, Chuan Qin, Xianghui Yu, Feng Gao
Publikováno v:
Viruses, Vol 12, Iss 2, p 163 (2020)
Non-human primates (NHP) are the only animal model suitable to evaluate the protection efficacy of HIV-1 vaccines. It is important to understand how and when neutralizing antibodies (nAbs) with specificities similar to those of human broadly neutrali
Externí odkaz:
https://doaj.org/article/9d103018fee241179a507237b8e1c4b0
Akademický článek
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Akademický článek
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Autor:
Anna C. Smith, Hector Cervera Benet, Ross C. Larue, Geraldine Vilmen, Alon Herschhorn, Rajni Kant Shukla, Amit Sharma
Publikováno v:
mBio
Infection of rhesus macaques with simian-human immunodeficiency viruses (SHIVs) is the preferred model system for vaccine development because SHIVs encode HIV-1 envelope glycoproteins (Env) – a key target of HIV-1 neutralizing antibodies. Since the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9aba467ba3afa0b2b7fdb0750cc94f
https://doi.org/10.1128/mbio.02752-21
https://doi.org/10.1128/mbio.02752-21
Autor:
Nishimura, Yoshiaki, Sadjadpour, Reza, Mattapallil, Joseph J., Igarashi, Tatsuhiko, Lee, Wendy, Buckler-White, Alicia, Roederer, Mario, Chun, Tae-Wook, Martin, Malcolm A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2009 May 01. 106(19), 8015-8020.
Externí odkaz:
https://www.jstor.org/stable/40482889
Publikováno v:
Viruses, Vol 10, Iss 6, p 333 (2018)
Improved vaccine-mediated protection against HIV-1 requires a thorough understanding of the mode of HIV-1 transmission and how various immune responses control transmission. Cell-associated HIV-1 is infectious and contributes to HIV-1 transmission in
Externí odkaz:
https://doaj.org/article/96e4a8848b2b42aca4ddc24dfdf89df3