Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Simi M, Chacko"'
Autor:
Karuppaiyah Selvendiran, Simi M. Chacko, M. Lakshmi Kuppusamy, Mahmood Khan, Shabnam Ahmed, Periannan Kuppusamy
Publikováno v:
American Journal of Physiology-Cell Physiology. 299:C1562-C1570
Stem cells transplanted to the ischemic myocardium usually encounter massive cell death within a few days of therapy. Hypoxic preconditioning (HPC) is currently employed as a strategy to prepare stem cells for increased survival and engraftment in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cecc49f2161fc62bd92201e2271fc5de
https://doi.org/10.1152/ajpcell.00221.2010
https://doi.org/10.1152/ajpcell.00221.2010
Autor:
Simi M. Chacko, Sheik Wisel, M. Lakshmi Kuppusamy, I. Krishna Mohan, Periannan Kuppusamy, Benjamin Sun, Kálmán Hideg, Mahmood Khan, Brian K. Rivera
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 329:543-550
Stem cell transplantation is a possible therapeutic option to repair ischemic damage to the heart. However, it is faced with a number of challenges including the survival of the transplanted cells in the ischemic region. The present study was designe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a61567191d961d03b0667355728c08
https://doi.org/10.1124/jpet.109.150839
https://doi.org/10.1124/jpet.109.150839
Autor:
Sheik Wisel, Vijay Kumar Kutala, Simi M. Chacko, Pawel Kwiatkowski, Mahmood Khan, Iyyapu Krishna Mohan, Deepti S. Vikram, Jay L. Zweier, M. Lakshmi Kuppusamy, Periannan Kuppusamy
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H2129-H2139
It is unclear whether oxygen plays a role in stem cell therapy. Hence, the determination of local oxygenation (Po2) in the infarct heart and at the site of transplantation may be critical to study the efficacy of cell therapy. To demonstrate this, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877723f751531bfc157376e53dd55efd
https://doi.org/10.1152/ajpheart.00677.2007
https://doi.org/10.1152/ajpheart.00677.2007
Autor:
Periannan Kuppusamy, Pawel Kwiatkowski, Vijay Kumar Kutala, M. Lakshmi Kuppusamy, Mahmood Khan, Benjamin Sun, Ramasamy P. Pandian, Richard W. Burry, Simi M. Chacko, Sheik Wisel
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 292:H1254-H1261
We report the labeling (internalization) of skeletal myoblasts (SMs) with a novel class of oxygen-sensing paramagnetic spin probe for noninvasive tracking and in situ monitoring of oxygenation in stem cell therapy using electron paramagnetic resonanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390214c039021e2cbb0d3ef11f84c6c5
https://doi.org/10.1152/ajpheart.01058.2006
https://doi.org/10.1152/ajpheart.01058.2006
Autor:
Simi M. Chacko, Periannan Kuppusamy
Publikováno v:
Stem Cell Therapy for Organ Failure ISBN: 9788132221098
The field of stem-cell therapy holds immense potential to develop as a new branch of medicine that can not only enhance endogenous stem-cell repair processes in the human body, but also be able to supplement with isolated and expanded multipotent aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2934a61cd79fa5e900b3f312569a451f
https://doi.org/10.1007/978-81-322-2110-4_2
https://doi.org/10.1007/978-81-322-2110-4_2
Autor:
Simi M. Chacko, Periannan Kuppusamy
Publikováno v:
Cardiovascular Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::533afe5945e84e7c15af8b6bc3d42d8f
https://doi.org/10.1201/b14663-15
https://doi.org/10.1201/b14663-15
Autor:
Ramasamy P, Pandian, Simi M, Chacko, M Lakshmi, Kuppusamy, Brian K, Rivera, Periannan, Kuppusamy
Publikováno v:
Advances in experimental medicine and biology. 701
A new paramagnetic crystalline material, namely, lithium naphthalocyanine (LiNc), whose electron-paramagnetic-resonance (EPR) line width is highly sensitive to oxygen content, has been evaluated for use as oximetry probe in cells and tissues. Previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8da604d04a7e33cbe24fb401b86f9f6
https://pubmed.ncbi.nlm.nih.gov/21445766
https://pubmed.ncbi.nlm.nih.gov/21445766
Autor:
Brian K. Rivera, Simi M. Chacko, Periannan Kuppusamy, M. Lakshmi Kuppusamy, Ramasamy P. Pandian
Publikováno v:
Oxygen Transport to Tissue XXXII ISBN: 9781441977557
A new paramagnetic crystalline material, namely, lithium naphthalocyanine (LiNc), whose electron-paramagnetic-resonance (EPR) line width is highly sensitive to oxygen content, has been evaluated for use as oximetry probe in cells and tissues. Previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b881211f046948013e09b5cbd3bd0b4
https://doi.org/10.1007/978-1-4419-7756-4_5
https://doi.org/10.1007/978-1-4419-7756-4_5
Autor:
Anna Bratasz, Brian K. Rivera, M. Lakshmi Kuppusamy, Simi M. Chacko, Ramasamy P. Pandian, Periannan Kuppusamy, Karuppaiyah Selvendiran, Mahmood Khan, Saradhadevi Varadharaj
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 296(5)
Stem cell therapy for myocardial tissue repair is limited by the poor survival of transplanted cells, possibly because of inadequate supply of oxygen and nutrients. The purpose of this study was to assess the oxygenation level and functional recovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3640523982e16ce317e1adb77aed71c
https://pubmed.ncbi.nlm.nih.gov/19329768
https://pubmed.ncbi.nlm.nih.gov/19329768
Autor:
Mahmood, Khan, Vijay Kumar, Kutala, Sheik, Wisel, Simi M, Chacko, M Lakshmi, Kuppusamy, Pawel, Kwiatkowski, Periannan, Kuppusamy
Publikováno v:
Advances in experimental medicine and biology. 614
We have developed a noninvasive EPR (electron paramagnetic resonance) oximetry, based on a new class of oxygen-sensing nano-particulate probe (LiNc-BuO), for simultaneous monitoring of stem-cell therapy and in situ oxygenation (partial pressure of ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8e34a4473ccf4e7dffed98e5063557e
https://pubmed.ncbi.nlm.nih.gov/18290313
https://pubmed.ncbi.nlm.nih.gov/18290313