Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Simi Kobi"'
Autor:
Yael Litvak, Shir Sharon, Meirav Hyams, Li Zhang, Simi Kobi, Naama Katsowich, Shira Dishon, Gabriel Nussbaum, Na Dong, Feng Shao, Ilan Rosenshine
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006472 (2017)
Enteropathogenic Escherichia coli (EPEC), a common cause of infant diarrhea, is associated with high risk of mortality in developing countries. The primary niche of infecting EPEC is the apical surface of intestinal epithelial cells. EPEC employs a t
Externí odkaz:
https://doaj.org/article/30bff767f32c4757ab9cd6ee8e27bf92
Autor:
Chen Nadler, Kobi Baruch, Simi Kobi, Erez Mills, Gili Haviv, Marganit Farago, Irit Alkalay, Sina Bartfeld, Thomas F Meyer, Yinon Ben-Neriah, Ilan Rosenshine
Publikováno v:
PLoS Pathogens, Vol 6, Iss 1, p e1000743 (2010)
The complex host-pathogen interplay involves the recognition of the pathogen by the host's innate immune system and countermeasures taken by the pathogen. Detection of invading bacteria by the host leads to rapid activation of the transcription facto
Externí odkaz:
https://doaj.org/article/9eac1750fc73432c82693a3a46d34e7e
Autor:
Yaakov Socol, Saurabh Bhattacharya, Simi Kobi, Naama Katsowich, Ritesh Ranjan Pal, Ilan Rosenshine, Gideon Mamou, Sigal Ben-Yehuda, Amit K. Baidya
Publikováno v:
Cell
Microbiota and intestinal epithelium restrict pathogen growth by rapid nutrient consumption. Weinvestigated how pathogens circumvent this obstacle to colonize the host. Utilizing enteropathogenicE.coli(EPEC), we show that host-attached bacteria obtai
Autor:
Simi Kobi, Erez Mills, Tamar Kahan, Ritesh Ranjan Pal, Ilan Rosenshine, Naama Katsowich, Netanel Elbaz
Publikováno v:
Science (New York, N.Y.). 355(6326)
Touchdown for gut pathogen virulence Escherichia coli is transformed from a commensal organism into a pathogen by acquisition of genetic elements called pathogenicity islands (PAIs). Katsowich et al. investigated how the PAI virulence genes of entero
Publikováno v:
Cell Host & Microbe. 3:104-113
Summary Bacteria use type III secretion systems (TTSS) to translocate effector proteins into host cells. Better understanding of the TTSS and its effectors' functions will require assays to measure their activities in vivo and in real time. We design
Publikováno v:
Infection and Immunity. 74:839-849
Upon infection of host cells, enteropathogenic Escherichia coli (EPEC) delivers a set of effector proteins into the host cell cytoplasm via the type III secretion system (TTSS). The effectors subvert various host cell functions. We found that EPEC in
Autor:
Erez Mills, Thomas F. Meyer, Sina Bartfeld, Kobi Baruch, Yinon Ben-Neriah, Marganit Farago, Simi Kobi, Chen Nadler, Irit Alkalay, Gili Haviv, Ilan Rosenshine
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 1, p e1000743 (2010)
PLoS Pathogens, Vol 6, Iss 1, p e1000743 (2010)
The complex host-pathogen interplay involves the recognition of the pathogen by the host's innate immune system and countermeasures taken by the pathogen. Detection of invading bacteria by the host leads to rapid activation of the transcription facto
Publikováno v:
Journal of Molecular Biology. 218:723-733
The bacteriophage λ cIII gene product is an early regulatory protein that participates in the lysis-lysogeny decision of the phage following infection. We have previously shown that the translation of the cIII gene is determined by two unique factor
Autor:
Ilan Rosenshine, Stuart Knutton, Maya Elgrably-Weiss, Matthew K. Waldor, Tatiana Berdichevsky, Ophir Ilan, Yulia Shifrin, Cecilia Abe, Kobi Baruch, Shoshy Altuvia, Chihiro Sasakawa, Chen Nadler, Jennifer M. Ritchie, Simi Kobi, Adi Peleg, Gal Yerushalmi
Publikováno v:
Journal of bacteriology. 190(14)
Enterohemorrhagic and enteropathogenic Escherichia coli (EHEC and EPEC, respectively) strains represent a major global health problem. Their virulence is mediated by the concerted activity of an array of virulence factors including toxins, a type III
Publikováno v:
Nucleic Acids Research. 8:4327-4336
A Lambda phage was constructed in which the structural gene for beta galactosidase is fused to a DNA segment carrying the ribosomal promoter rrnB of E. coli. In this hybrid operon beta galactosidase synthesis in vitro is repressed by ppGpp. Repressio