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Corrigendum to “Development of a generic zebrafish embryo PBPK model and application to the developmental toxicity assessment of valproic acid analogs” [Reprod. Toxicol. 93 (2020) 219⬜229]

Autor: Siméon, Ségolène, Brotzmann, Katharina, Fisher, Ciarán, Gardner, Iain, Silvester, Steve, Maclennan, Richard, Walker, Paul, Braunbeck, Thomas, Bois, Frederic Y. ^*

Publikováno v: In Reproductive Toxicology December 2020 98:300-303

Integration of new approach methods in a structure based read-across for DART effects

Autor: Kroese, E.D., Brotzmann, Katharina, Koch, Bjorn, Waldmann, Tanja, Kisitu, J., Jaklin, M., van Vugt, Barbara, Fischer, C., Bois, Frédéric Y., Simeon, Ségolène, Long, Tony, Norinder, Ulf, van Der Burg, Bart, Wolterbeek, A.

Publikováno v: 55. Congress of the European Societies of Toxicology (EUROTOX 2019)
55. Congress of the European Societies of Toxicology (EUROTOX 2019), Sep 2019, Helsinki, Finland. pp.S27-S28

Read-across is one of the most often applied alternative tools for hazard assessment, in particular for complex endpoints such as toxicity after repeated exposure or developmental and reproductive toxicity. We have applied this approach to a series o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1f32a17fb646e65a5f06ffabd0ad3929
https://hal-ineris.archives-ouvertes.fr/ineris-03237278

PBPK modeling of zebrafish embryo for reprotoxicity assessment of valproic acid and some of its analogs

Autor: Simeon, Ségolène, Brotzmann, Katharina, Fischer, C., Gardner, I., Braunbeck, Thomas, Silvester, S., Maclennan, Richard, Bois, Frédéric Y.

Publikováno v: Abstracts book of the ECOPA 2018 Symposium "How new experimental tools in life sciences challenge the 3Rs vision"
ECOPA 2018 Symposium "How new experimental tools in life sciences challenge the 3Rs vision"
ECOPA 2018 Symposium "How new experimental tools in life sciences challenge the 3Rs vision", Nov 2018, Paris, France. pp.52

Introduction: Understanding and predicting chemical effects on development and reproduction is a complex challenge. The zebrafish embryo is an in vitro test system increasingly used for its transparency, short development time, easy husbandry and gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2d0026eef88c4bff782346f4d721c87d
https://hal-ineris.archives-ouvertes.fr/ineris-03239687