Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sima Nasizadeh"'
Publikováno v:
Experimental Cell Research. 308:254-264
Polyamines are organic cations, which are considered essential for normal cell cycle progression. This view is based on results from numerous studies using a variety of enzyme inhibitors or polyamine analogues interfering with either the metabolism o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562bad5fbb00d7c5d4d16370a82cb91f
https://doi.org/10.1016/j.yexcr.2005.04.027
https://doi.org/10.1016/j.yexcr.2005.04.027
Publikováno v:
Molecular and biochemical parasitology. 173(2)
Blood-stage malarial parasites (Plasmodium falciparum) digest large quantities of host haemoglobin during their asexual development in erythrocytes. The haemoglobin digestion pathway, involving a succession of cleavages by various peptidases, appears
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0dfe64209c2cf518fd0cbbd1eb6017
https://pubmed.ncbi.nlm.nih.gov/20478341
https://pubmed.ncbi.nlm.nih.gov/20478341
Publikováno v:
Amino acids. 34(3)
Ornithine decarboxylase (ODC) has a very fast turnover in mammalian cells, but is a stable enzyme in T. brucei and other trypanosmatid parasites like Leishmania donovani. However, Crithidia fasciculata, which is a phylogenetically closely related try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54986c47df5a544f56a9544c31936de4
https://pubmed.ncbi.nlm.nih.gov/17514492
https://pubmed.ncbi.nlm.nih.gov/17514492
Autor:
Sima Nasizadeh, Lo Persson
Publikováno v:
FEBS letters. 553(1-2)
The activity of S-adenosylmethionine decarboxylase (AdoMetDC) in Crithidia fasciculata was shown to be correlated to the growth of the parasite. An increase in activity was observed during exponential growth. Inhibition of protein synthesis induced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc00cb21b9d2fcab1d0876915f0c5dd8
https://pubmed.ncbi.nlm.nih.gov/14550560
https://pubmed.ncbi.nlm.nih.gov/14550560
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 13(5)
Mammalian ornithine decarboxylase (ODC), which catalyses the first step in polyamine biosynthesis, has a very fast turnover. It is degraded by the 26S proteasome in an ubiquitin-independent process and the degradation is stimulated by polyamines in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f264dfe425234ddf6bc256b24cbd661
https://pubmed.ncbi.nlm.nih.gov/14586177
https://pubmed.ncbi.nlm.nih.gov/14586177
Publikováno v:
Biochemical Society transactions. 31(2)
Interestingly, there is a major difference in turnover rate between ornithine decarboxylases (ODCs) from various trypanosomatids. ODCs from Trypanosoma brucei and Leishmania donovani are both stable proteins, whereas ODC from Crithidia fasciculata is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d2a9be3a942c985421375e9e138a25
https://pubmed.ncbi.nlm.nih.gov/12653649
https://pubmed.ncbi.nlm.nih.gov/12653649
Autor:
Anders Jeppsson, Anna Wendt, Lo Persson, Holmgren J, Sima Nasizadeh, Eva Lövkvist Wallström, Dartsch C
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b728f6b877a6284fa92ac491b0697df
https://pubmed.ncbi.nlm.nih.gov/10047785
https://pubmed.ncbi.nlm.nih.gov/10047785