Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sima Mirilashvili"'
Autor:
Alex Aizikovich, Alexander Konson, Nili Schutz, Alina Shitrit, Avihai Yacovan, Sima Mirilashvili, Rachel Ozeri, Daniel Sherman, Osnat Bohana-Kashtan, Oren M. Becker, Tzofit Kehat, Vered Behar, Efrat Ben-Zeev
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:6460-6468
Cancer cells preferentially use glycolysis rather than oxidative phosphorylation for their rapid growth. They consume large amount of glucose to produce lactate even when oxygen is abundant, a phenomenon known as the Warburg effect. This metabolic ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79338c894668e99725151e301339abfd
https://doi.org/10.1016/j.bmcl.2012.08.054
https://doi.org/10.1016/j.bmcl.2012.08.054
Publikováno v:
European Journal of Organic Chemistry. 2010:4671-4686
Peptidyl olefin peptidomimetics serve as biologically active compounds or as intermediates for other peptidyl isosteres. The N-terminal side of the C=C bond could be easily prepared in an optically pure form from α-amino acids. Synthesis of C-termin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5835399bdbde1af4cbd81018e0db5d2
https://doi.org/10.1002/ejoc.201000539
https://doi.org/10.1002/ejoc.201000539
Autor:
Vered Behar, Efrat Ben-Zeev, Avihai Yacovan, Alexander Konson, Sima Mirilashvili, Osnat Bohana-Kashtan, Nili Schutz, Alina Shitrit, Oren M. Becker, Tzofit Kehat, Rachel Ozeri
Publikováno v:
Cancer Research. 72:3219-3219
Pyruvate kinase (PK) M2 which catalyzes the last step in glycolysis, is the alternative spliced isoform expressed in cancer cells, and a key player in exerting the Warburg effect. One of the mechanisms by which PKM2 modulate cancer cell metabolism is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6ebf05a900bd11a04cfadce492af3cd
https://doi.org/10.1158/1538-7445.am2012-3219
https://doi.org/10.1158/1538-7445.am2012-3219