Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Sima MANSOORI DERAKHSHAN"'
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-10 (2022)
Abstract Background Hereditary hearing loss (HHL) is a common heterogeneous disorder affecting all ages, ethnicities, and genders. The most common form of HHL is autosomal recessive non-syndromic hearing loss (ARNSHL), in which there is no genotype
Externí odkaz:
https://doaj.org/article/45517f3c02e44a6b9667da9580b02ac3
Autor:
Mahsa Farjami, Reza Asadi, Fahimeh Afzal Javan, Malihe Alimardani, Saeed Eslami, Sima Mansoori Derakhshan, Atieh Eslahi, Majid Mojarad
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 23, Iss 7, Pp 841-848 (2020)
MYO15A is the third most crucial gene in hereditary sensorineural hearing loss after GJB2 and SLC26A4. In the present study, we reviewed the prevalence of MYO15A mutations in patients with autosomal recessive non-syndromic hearing loss (ARNSHL). In t
Externí odkaz:
https://doaj.org/article/665f9fff3cc149f6b00d08af0fc5219e
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 20, Iss 6, Pp 700-707 (2017)
Objective(s): The use of antisense oligonucleotides (AOs) to restore normal splicing by blocking the recognition of aberrant splice sites by the spliceosome represents an innovative means of potentially controlling certain inherited disorders affecte
Externí odkaz:
https://doaj.org/article/e852f1d79fa94c998d933da08364c254
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 18, Iss 2, Pp 105-109 (2017)
Background: Nesfatin-1, a newly discovered calcium and DNA binding peptide, originate from nucleobindin 2 (NUCB2) precursors and expressed by central and peripheral nervous system, and peripheral tissues such as digestive organs and adipose tissues.
Externí odkaz:
https://doaj.org/article/0f63b6c30fdc45a8aff15656ba5e0d01
Autor:
Elham HASSANI, Mahmood SHEKARI KHANIANI, Mojtaba SAFFARI, Amirnader EMAMI RAZAVI, Reza SHIRKOOHI, Sima MANSOORI DERAKHSHAN
Publikováno v:
Iranian Journal of Public Health, Vol 48, Iss 9 (2019)
Background: Epithelial ovarian cancer (EOC), is the fatal form of gynecological cancer. Almost 70% of ovarian cancer patients are detected at an advanced stage (III-IV) with metastases. Epithelial‑mesenchymal transition (EMT) is a critical process
Externí odkaz:
https://doaj.org/article/605f154a75704cf5a57b36a81dd1872d
Autor:
Mohammad Reza Ranjouri, Parisa Aob, Sima Mansoori Derakhshan, Mahmoud Shekari Khaniani, Hossein Chiti, Ali Ramazani
Publikováno v:
BioImpacts, Vol 6, Iss 4, Pp 187-193 (2016)
Introduction: A variety of genetic predisposing factors and environmental factors are known to influence the pathogenesis of type-1 diabetes (T1D). This study intended to investigate the association of cytotoxic T-lymphocyte associated protein 4 (CTL
Externí odkaz:
https://doaj.org/article/b5097cefff184234877424bcff0da7c0
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 5, Iss 1, Pp 137-140 (2015)
Purpose: Association between HLA-DR4–DQ8 haplotype and type 1 Diabetes Mellitus (DM-1A) was investigated in children of East Azerbaijan state of Iran because such an association has not been previously studied in this population. Methods: HLA-typi
Externí odkaz:
https://doaj.org/article/193b987c82fb4947b0f671b13df87b5d
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 4, Iss 1, Pp 91-95 (2014)
Purpose: Stem cell factor (SCF) plays an important role in the survival, proliferation and differentiation of hematopoietic stem cells and progenitor cells. Potential therapeutic applications of SCF include hematopoietic stem cell mobilization, exviv
Externí odkaz:
https://doaj.org/article/71cb0a6e88f6446c9183ce39c6a8cb25
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 17, Iss 2, Pp 108-111 (2014)
Objective(s): Breast cancer is the most common cancer in women. Every year, one million new cases are reported worldwide, representing 18% of the total number of cancer in women. Hereditary BRCA1 and BRCA2 mutations account for about 60% of inherited
Externí odkaz:
https://doaj.org/article/52a9bed597984fbeaad9af16f03c0a5f
Publikováno v:
Journal of Analytical Research in Clinical Medicine, Vol 1, Iss 1, Pp 2-17 (2013)
BACKGROUND: Fragile X syndrome is a genetic mental retardation syndrome caused by an unstable mutation in thefragile X mental retardation 1 gene (FMR1) on the X chromosome. FMR1 CGG repeat alleles are categorized accordingto number as normal, interme
Externí odkaz:
https://doaj.org/article/937ad357ae32418f818d34fc9928b90c