Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sima Ardalan Khales"'
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers worldwide. Overexpression of EMT master transcription factors can promote differentiated cells to undergo cancer reprogramming processes and acquire a stem
Externí odkaz:
https://doaj.org/article/4a46a4c9d5f6422bb35bcfe0d9b33b54
Autor:
Sima, Ardalan Khales, Azadeh, Aarabi, Mohammad Reza, Abbaszadegan, Mohammad Mahdi, Forghanifard
Publikováno v:
Iranian biomedical journal.
INPP5A is involved in different cellular events, including cell proliferation. Since INPP5A, HLAG1, IL-10, and MMP-21 genes play fundamental roles in ESCC tumorigenesis, we aimed in this study to clarify the possible interplay of these genes and expl
Autor:
Dorsa Morshedi Rad, Sima Ardalan Khales, Mohammad Mahdi Forghanifard, Shirin Azaraz, Mohammad Reza Abbaszadegan
BackgroundMastermind-like 1 (MAML1) is the main transcriptional co-activator of Notch signaling pathway. It plays essential roles in several pathways including MEF2C, p53, Nf-кB and Wnt/β-catenin. TWIST1 is known as a regulator of epithelial mesenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58e6cf0ac3a687d94f3279cade64921
https://hdl.handle.net/10453/148396
https://hdl.handle.net/10453/148396
Autor:
GholamReza Karami Madani, Mohammad Mahdi Forghanifard, Mohammad Reza Abbaszadegan, Mehdi Molavi, Abolfazl Rad, Sima Ardalan Khales
Publikováno v:
Journal of Gastrointestinal Cancer. 49:437-441
Enhancer of zeste homolog 2 (EZH2), a stemness factor, plays roles in regulation of cell differentiation and embryonic development as well as cancer progression. Deregulation of EZH2 in cancers is correlated with tumor cell invasiveness, metastasis,
Publikováno v:
Biochimie. 163
Aberrant expression of cancer testis antigens (CTAs) is reported in tumors, especially those with stemness properties. A number of CTAs can induce epithelial mesenchymal transition (EMT) process and promote cancer stem cells (CSCs) characteristics. W
Autor:
Masoud Homayouni-Tabrizi, Mohammad Mahdi Forghanifard, Mohammad Reza Abbaszadegan, Moein Farshchian, Sima Ardalan Khales, Abolfazl Rad
Publikováno v:
Pathology & Oncology Research. 23:85-90
Epithelial-mesenchymal transition (EMT) is crucial for specific morphogenetic movements during embryonic development as well as pathological processes of tumor cell invasion and metastasis. TWIST and SNAIL play vital roles in both developmental and p
Publikováno v:
Gene Expression Patterns. 37:119127
Twist-related protein 1 (TWIST1), a highly conserved basic helix-loop-helix transcription factor, stimulates epithelial-mesenchymal transition (EMT) and plays a crucial role in the regulation of the extracellular matrix (ECM) and cell-cell adhesion.
Autor:
Sahar Ardalan Khales, Aliraz Tavassoli, Sima Kadkhodayan, Fatemeh Homaei Shandiz, Sima Ardalan Khales, Nourieh Sharifi
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 16:471-474
Background Male and female breast cancers were investigated for variation in the clinicopathologic characteristics and expression of steroid hormone receptors in the northeast of Iran. Materials and methods Tumor specimens of 17 males and 338 females
Autor:
Ehsan Ebrahimi, Eisa Jahanzad, Sima Ardalan Khales, Mohammad Mahdi Forghanifard, Sahar Ardalan Khales
Publikováno v:
Asia-Pacific journal of clinical oncology. 14(5)
AIMS Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide with considerable morbidity and mortality. Invasion and metastasis of HNSCC is a complex process involving multiple molecules and signaling pathways. Twist
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 33:e22262
SALL4, as a stemness marker, plays a key role in the maintenance of pluripotency and self-renewal of cancer stem cells. To elucidate probable linkage between SALL4 stemness marker and bone morphogenetic protein (BMP) cell signaling pathway, we aimed