Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sim Truong"'
Autor:
Philippe Solal-Celigny, Martin Weisser, Ru-Fang Yeh, Tobias Benthaus, Gudrun Mellert, John Catalano, Wolfgang Hiddemann, Stefan K. Bohlander, Debraj GuhaThakurta, Guillemette Duchateau-Nguyen, Purvi M. Kakadia, Tadeusz Robak, Lin Wu, Evelyn Zellmeier, Marco Montillo, Sabine Lohmann, David Dornan, Nancy Patten, Christian H. Geisler, Sim Truong, Giuseppe Palermo, Stephanie Schneider, Jan Braess, Galina Salogub, Annika Dufour, Anna Dmoszynska, Karsten Spiekermann
Publikováno v:
Blood. 121:3650-3657
In chronic lymphocytic leukemia (CLL) patients, disruptions of the TP53 tumor suppressor pathway by 17p13 deletion (del17p), somatic TP53 mutations, or downregulation of microRNA-34a have been associated with a poor prognosis. So far, the impact of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a26bd18c78baabcd424eb5ee6c60f27
https://doi.org/10.1182/blood-2012-10-458695
https://doi.org/10.1182/blood-2012-10-458695
Autor:
Alexandra Oltová, Sim Truong, Jana Kotašková, Jana Šmardová, Jiri Mayer, Boris Tichy, Jitka Malčíková, Šárka Pospíšilová, Nancy Patten, Šárka Pavlová, Karla Plevová, Eva Divíšková, Nikola Tom, Michael Doubek, Martin Trbušek, Yvona Brychtová, Barbara Kantorová
Publikováno v:
Tumor Biology
TP53 gene defects represent a strong adverse prognostic factor for patient survival and treatment resistance in chronic lymphocytic leukemia (CLL). Although various methods for TP53 mutation analysis have been reported, none of them allow the identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47badf6d874ca6b9334adf55bb1b216b
https://pubmed.ncbi.nlm.nih.gov/25527155
https://pubmed.ncbi.nlm.nih.gov/25527155
Autor:
Alfonso Piciocchi, Sabina Chiaretti, Nancy Patten, Marilisa Marinelli, Anna Guarini, Simona Santangelo, Maria Stefania De Propris, Monica Messina, Simona Tavolaro, Jeffrey Lawrence, Francesca Romana Mauro, Isabella Torrente, Nadia Peragine, Sim Truong, Robin Foà, Ilaria Del Giudice, Mauro Nanni, Emanuela M. Ghia
Given that TP53 alterations predict prognosis and response to therapy in chronic lymphocytic leukemia (CLL), screening for TP53 mutations has an increasing role in patient management. TP53 direct sequencing is a time-consuming method, while the Ampli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76ed6f4ff001bd89bde81cb9e520a2b
http://hdl.handle.net/11573/379797
http://hdl.handle.net/11573/379797
Autor:
Branko Brdar, Zvonimir Medverec, Lin Wu, Masaaki Moriya, Neda Slade, Karla Tomić, Arthur P. Grollman, Sim Truong, Bojan Jelaković, Andrea Fernandes
This study was designed to establish the TP53 mutational spectrum of aristolochic acid (AA), examined in the context of endemic (Balkan) nephropathy, an environmental disease associated with transitional cell (urothelial) carcinomas of the upper urin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc48558ed366d7371a00d276cf60cb5
https://www.bib.irb.hr/526683
https://www.bib.irb.hr/526683
Autor:
Nancy Patten, Hanne Helfrich, Jana Šmardová, Andrew R. Pettitt, Patrick Hoth, Rachel E. Ibbotson, Petr Kuglík, Sonja Häbe, Jitka Malčíková, Axel Benner, Jiří Mayer, Tina Denzel, Thorsten Zenz, Maxi Fuge, Lin Wu, Šárka Pospíšilová, Hartmut Döhner, Sim Truong, Stephan Stilgenbauer, Dominik Vollmer, Michael Hallek, Ian Tracy, Maria Heuberger, Anne Gardiner, Martin Trbušek, David Oscier, Thierry Soussi, Ke Lin
Publikováno v:
Leukemia. 24(12)
The TP53 mutation profile in chronic lymphocytic leukemia (CLL) and the correlation of TP53 mutations with allele status or associated molecular genetics are currently unknown. We performed a large mutation analysis of TP53 at four centers and charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7663f9b1cfc2bc06df73144c9be7bf11
https://pubmed.ncbi.nlm.nih.gov/20861914
https://pubmed.ncbi.nlm.nih.gov/20861914
Autor:
Martin Trbušek, Katerina Stano-Kozubik, Michael Doubek, Karol Pál, Ludmila Šebejová, Lin Wu, Barbara Kantorová, Nancy Patten, Jana Kminkova, Sim Truong, Barbora Dvorakova, Nikola Tom, Veronika Navrkalová, Šárka Pospíšilová, Jiri Mayer, Boris Tichy, Jitka Malčíková, Jana Šmardová
Publikováno v:
Blood. 120:3911-3911
Abstract 3911 Background The adverse prognostic significance of p53 aberrations (gene deletion at locus 17p13.1 and/or TP53 mutations) has been already proven in chronic lymphocytic leukemia (CLL). In contrast to the standardized examination of the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7922b4f9b5c475d3688c4a12d015221a
https://doi.org/10.1182/blood.v120.21.3911.3911
https://doi.org/10.1182/blood.v120.21.3911.3911
Autor:
Nancy Patten, Boris V. Afanasiev, Tadeusz Robak, Sim Truong, Lin Wu, Galina Salogub, Guillemette Duchateau-Nguyen, Gudrun Mellert, Annika Dufour, Philippe Solal-Celigny, Ming Lin, Giuseppe Palermo, Purvi M. Kakadia, Marco Montillo, Martin Weisser, Ru-Fang Yeh, David Dornan, Anna Dmoszynska, Christian H. Geisler, Stephanie Schneider, Karsten Spiekermann, Stefan K. Bohlander, Evelyn Zellmeier, Wolfgang Hiddemann, John G. Catalano, Jan Braess
Publikováno v:
Blood. 118:2445-2445
Abstract 2445 Chronic lymphocytic leukemia (CLL) patients with a deletion of the TP53 tumor supressor gene located at 17p13 have a poor prognosis in first line chemotherapy regimens. Recent studies indicated somatic TP53 mutations as a prognostic fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65c7a5680c5223b8d586e21371bce34
https://doi.org/10.1182/blood.v118.21.2445.2445
https://doi.org/10.1182/blood.v118.21.2445.2445
Autor:
Galina Salogub, Gudrun Mellert, Martin Weisser, Ru-Fang Yeh, Boris V. Afanasiev, Sim Truong, Guillemette Duchateau-Nguyen, Tadeusz Robak, David Dornan, Ming Lin, Evelyn Zellmeier, Philippe Solal-Celigny, Marco Montillo, Annika Dufour, Nancy Patten, Christian H. Geisler, Karsten Spiekermann, Lin Wu, John G. Catalano, Jan Braess, Wolfgang Hiddemann, Anna Dmoszynska, Purvi M. Kakadia, Stephanie Schneider, Giuseppe Palermo, Stefan K. Bohlander
Publikováno v:
Blood. 118:3521-3521
Abstract 3521 MicroRNA-34a (miR-34a), a direct downstream target of the tumor suppressor TP53 is upregulated in chronic lymphocytic leukemia (CLL) cells and leads to apoptosis and cell cycle arrest. Previous studies found low miR-34a expression level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9637cb92d04700f3cfdcab64845c930
https://doi.org/10.1182/blood.v118.21.3521.3521
https://doi.org/10.1182/blood.v118.21.3521.3521
Akademický článek
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Autor:
James S. Malter, Ronald S. Go, Santiago Moreno, Jeffrey T. Malik, Fan Zhou, Jeff Chang, Miguel A. Piris, Carlo Visco, Nancy Patten, Michelle A. Waknitz, Xianfeng Zhao, Eric D. Hsi, William M. Rehrauer, Attilio Orazi, Yan Li, Govind Bhagat, William W.L. Choi, Matthew Twohig, Magdalena Czader, Suzanne M. Selvaggi, Cherie H. Dunphy, Alexander Tzankov, Kristin E. Hunt, Yong Li, Stacey S O'Neill, Jens C. Eickhoff, Huan-You Wang, Lin Wu, Jane N. Winter, Kazunori Kanehira, Sim Truong, Ken H. Young, Weina Chen, Gabrielle L. Rocque, Karen Dybkær, Michael Boe Møller, April Chiu, Brad S. Kahl
Publikováno v:
ResearcherID
Abstract 967 Mutations of the TP53 tumor suppressor gene are associated with a poor clinical outcome in DLBCL patients treated with CHOP. The impact of TP53 mutations on clinical outcome of DLBCL patients treated with Rituxan-CHOP has not been compre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1add423061e28a7e6cfe78b29880c6a1
https://doi.org/10.1182/blood.v114.22.967.967
https://doi.org/10.1182/blood.v114.22.967.967