Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Silvya Stuchi Maria Engler"'
Autor:
Jeniffer Farias Dos Santos, Bruna Letícia Freitas-Marchi, Gustavo Roncoli Reigado, Silvia Romano de Assis, Silvya Stuchi Maria Engler, Felipe Santiago Chambergo Alcalde, Viviane Abreu Nunes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Introduction: In skin traumas, such as burns, epidermal homeostasis is affected, often requiring clinical approaches. Different therapeutic strategies can be used including transplantation, besides the use of synthetic or natural materials with allog
Externí odkaz:
https://doaj.org/article/942037fbc04746c4a6aaf82aefca3794
Autor:
Priscilla Tobias Ribeiro, Tatiana do Nascimento Pedrosa, Francisco Celio Maia Chaves, Lucindo José Quintans-Júnior, Adriano Antunes de Souza Araújo, Marne Carvalho de Vasconcellos, Silvya Stuchi Maria-Engler, Cláudia Cândida Silva, Felipe Moura Araújo da Silva, Héctor Henrique Ferreira Koolen, Emerson Silva Lima, Ádley Antonini Neves de Lima
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract Passiflora nitida Kunth, an Amazonian Passiflora species, is little studied, although the specie’s high biological potential. Herein the plant’s pharmacognostic characterization, extract production, antioxidant potential evaluation, and
Externí odkaz:
https://doaj.org/article/7a9f12fb60524d9bbad42d583ccc30e8
Autor:
Carlos Poblete Jara, Beatriz de Andrade Berti, Natália Ferreira Mendes, Daiane Fátima Engel, Ariane Maria Zanesco, Gabriela Freitas Pereira de Souza, Renan de Medeiros Bezerra, Julia de Toledo Bagatin, Silvya Stuchi Maria-Engler, Joseane Morari, William H. Velander, Lício A. Velloso, Eliana Pereira Araújo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Glutamic acid is the main excitatory neurotransmitter acting both in the brain and in peripheral tissues. Abnormal distribution of glutamic acid receptors occurs in skin hyperproliferative conditions such as psoriasis and skin regeneration;
Externí odkaz:
https://doaj.org/article/7a05eb7d4bce492ead6effd029af47b2
Autor:
Inna Smalley, Eunjung Kim, Jiannong Li, Paige Spence, Clayton J. Wyatt, Zeynep Eroglu, Vernon K. Sondak, Jane L. Messina, Nalan Akgul Babacan, Silvya Stuchi Maria-Engler, Lesley De Armas, Sion L. Williams, Robert A. Gatenby, Y. Ann Chen, Alexander R.A. Anderson, Keiran S.M. Smalley
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 178-190 (2019)
Background: Melanoma is a heterogeneous tumour, but the impact of this heterogeneity upon therapeutic response is not well understood. Methods: Single cell mRNA analysis was used to define the transcriptional heterogeneity of melanoma and its dynamic
Externí odkaz:
https://doaj.org/article/7d086aa6efdb4ee5a9b2cf678b89c9e9
Autor:
Gustavo Henrique Oliveira da Rocha, Marina de Paula-Silva, Milena Fronza Broering, Pablo Rhasan dos Santos Scharf, Larissa Satiko Alcântara Sekimoto Matsuyama, Silvya Stuchi Maria-Engler, Sandra Helena Poliselli Farsky
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Ulcerative colitis and Crohn’s disease are chronic inflammatory bowel diseases (IBDs) which burden health systems worldwide; available pharmacological therapies are limited and cost-intensive. Use of peroxisome proliferator activated-receptor γ (P
Externí odkaz:
https://doaj.org/article/b0b7383894b545aa80a7b09c26faf4b2
Autor:
Larissa A. C. Carvalho, Rodrigo G. Queijo, Alexandre L. B. Baccaro, Ádamo D. D. Siena, Wilson A. Silva, Tiago Rodrigues, Silvya Stuchi Maria-Engler
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 438 (2022)
Melanoma is the most aggressive type of skin cancer. Despite the available therapies, the minimum residual disease is still refractory. Reactive oxygen and nitrogen species (ROS and RNS) play a dual role in melanoma, where redox imbalance is involved
Externí odkaz:
https://doaj.org/article/a9efdf2ed80f4e799c98afcb481f51e3
Autor:
Keiran S.M. Smalley, J. William Harbour, Jonathan D. Licht, Uwe Rix, Silvya Stuchi Maria-Engler, Srikumar P. Chellappan, John M. Koomen, Bin Fang, Biswarup Saha, Fumi Kinose, Michael A. Durante, Michael F. Emmons, Fernanda Faião-Flores
Purpose:The clinical use of MEK inhibitors in uveal melanoma is limited by the rapid acquisition of resistance. This study has used multiomics approaches and drug screens to identify the pan-HDAC inhibitor panobinostat as an effective strategy to lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a6c9d3938006c6153d7b74edfa41ea
https://doi.org/10.1158/1078-0432.c.6528053
https://doi.org/10.1158/1078-0432.c.6528053
Autor:
Keiran S.M. Smalley, J. William Harbour, Jonathan D. Licht, Uwe Rix, Silvya Stuchi Maria-Engler, Srikumar P. Chellappan, John M. Koomen, Bin Fang, Biswarup Saha, Fumi Kinose, Michael A. Durante, Michael F. Emmons, Fernanda Faião-Flores
Supplementary Table S1- Antibodies used for protein expression in western blotting experiments Supplementary Table S2 - Assays used for gene expression in RT-qPCR experiments Supplementary Table S3 - Antibodies used for protein expression in immunofl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b6fa70918d2735b28b48bcd1f4dcb8
https://doi.org/10.1158/1078-0432.22471898
https://doi.org/10.1158/1078-0432.22471898
Autor:
Keiran S.M. Smalley, J. William Harbour, Jonathan D. Licht, Uwe Rix, Silvya Stuchi Maria-Engler, Srikumar P. Chellappan, John M. Koomen, Bin Fang, Biswarup Saha, Fumi Kinose, Michael A. Durante, Michael F. Emmons, Fernanda Faião-Flores
Supplemental Figure 1: Gene ontology network analysis of uveal melanoma cells following MEKi treatment (24h) and ABPP. Supplemental Figure 2: ET-3 increases nuclear accumulation of YAP in 92.1, Mel270, MP41 and OMM1 cells. Supplemental Figure 3: ET-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7b3c2c75bdf283a97ad482de2b351d
https://doi.org/10.1158/1078-0432.22471901
https://doi.org/10.1158/1078-0432.22471901
Autor:
Denisse Esther Mallaupoma Camarena, Larissa Satiko Alcântara Sekimoto Matsuyama, Silvya Stuchi Maria-Engler, Luiz Henrique Catalani
Publikováno v:
Nanomaterials, Vol 10, Iss 12, p 2528 (2020)
The development of products for topical applications requires analyses of their skin effects before they are destined for the market. At present, the ban on animal use in several tests makes the search for in vitro models (such as artificial skin) ne
Externí odkaz:
https://doaj.org/article/7ff221beeade416884150aafdb166980