Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Silvio Traversa"'
Autor:
Marina, Danilenko, Elaine, Stamp, Deborah D, Stocken, Akhtar, Husain, Monique, Zangarini, Amy, Cranston, Robert, Stones, Naomi, Sinclair, Kirsty, Hodgson, Susan A, Bowett, David, Roblin, Silvio, Traversa, Ruth, Plummer, Gareth, Veal, James A A, Langtry, Alan, Ashworth, John, Burn, Neil, Rajan
Publikováno v:
JAMA Dermatology
Key Points Question Can targeting tropomyosin receptor kinase with an existing topical kinase inhibitor, pegcantratinib, 0.5% (wt/wt), reduce cutaneous cylindroma tumor volume more than placebo? Findings In this phase 2 clinical trial that included 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::162ad5572e6966e5a9ed58689c41efa0
https://pubmed.ncbi.nlm.nih.gov/29955768
https://pubmed.ncbi.nlm.nih.gov/29955768
Autor:
Monique, Zangarini, Neil, Rajan, Marina, Danilenko, Philip, Berry, Silvio, Traversa, Gareth J, Veal
Publikováno v:
Bioanalysis
Aim: Pegcantratinib is a mini-PEGylated K252a derivative, under clinical evaluation as an anticancer agent acting through inhibition of the tropomyosin receptor kinase. A method for quantifying pegcantratinib in skin tumor biopsies of patients was re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4504cee3993df704ec1f522b6faa7b44
https://pubmed.ncbi.nlm.nih.gov/28111963
https://pubmed.ncbi.nlm.nih.gov/28111963
Autor:
Silvio Traversa, G. Inserra, Barbara Boscolo, L. Barbero, Elena Maria Ghibaudi, Rosa Pia Ferrari, Enzo Laurenti
Publikováno v:
Journal of Peptide Science. 11:401-409
An ESR investigation of the interaction of spin-labelled penetratin with heparin, heparansulfates and several phospholipid vesicle formulations is reported. Penetratin is a 16-aa peptide corresponding to the third helix of the Antennapedia homeodomai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910b02b1ad057e21223de0109292c931
https://doi.org/10.1002/psc.633
https://doi.org/10.1002/psc.633
Autor:
Silvio Aime, Davide Corpillo, Chiara Bracco, Luca Barbero, Silvio Traversa, Giuseppe Digilio, Gilles Piquet, Esposito P
Publikováno v:
Journal of the American Chemical Society. 125:3458-3470
Two novel mono-PEGylated derivatives of hGRF(1-29)-NH(2) [human growth hormone-releasing factor, fragment 1-29] have been synthesized by regio-specific conjugation of Lys(12) or Lys(21) to a monomethoxy-PEG(5000) chain (compounds Lys(12)PEG-GRF and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d3262ee4ca58690a17a163f51250eb
https://doi.org/10.1021/ja021264j
https://doi.org/10.1021/ja021264j
Autor:
Chicco D, Del Curto, Silvio Traversa, Silvio Aime, Esposito P, Chiara Bracco, Luca Barbero, Giuseppe Digilio
Publikováno v:
Journal of the American Chemical Society. 124:3431-3442
Antide is a decapeptide [(N-Ac-D-Nal(1)-D-Cpa(2)-D-Pal(3)-Ser(4)-Lys(Nic)(5)-D-Lys(Nic)(6)-Leu(7)-Ilys(8)-Pro(9)-D-Ala(10)-NH(2)] that acts in vivo as an antagonist of GnRH (gonadotropin-releasing hormone). The conformational behavior of antide has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7267ee86b41c41c36ba0e7847b0931c
https://doi.org/10.1021/ja0115464
https://doi.org/10.1021/ja0115464
Publikováno v:
Journal of Chromatography A. 944:141-148
In this paper we report the scale-up of the purification of poly(ethylene glycol) (PEG) derivatives of the growth hormone-releasing factor 1–29, from laboratory scale (100 mg of bulk starting material) to larger scale (3 g of bulk), through the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d574e3e5db2485fe9bbca18c60c8cf7
https://doi.org/10.1016/s0021-9673(01)01367-x
https://doi.org/10.1016/s0021-9673(01)01367-x
Publikováno v:
Journal of Mass Spectrometry. 35:210-217
The extent and distribution of N-glycosylation and the nature of most of the disulfide bond linkages were determined for bovine lactoperoxidase through proteolytic and glycolytic digestions combined with matrix-assisted laser desorption/ionization ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d35060c833481f8ded222b39535c75
https://doi.org/10.1002/(sici)1096-9888(200002)35:2<210::aid-jms931>3.0.co
https://doi.org/10.1002/(sici)1096-9888(200002)35:2<210::aid-jms931>3.0.co
Autor:
Andrea Morrione, Lilia Alberghina, Rita Grandori, David Metalli, Elena Sacco, Marco Vanoni, Romilde Manzoni, Michela Spinelli, Silvio Traversa, Maria Šamalikova
Publikováno v:
Biotechnology advances. 30(1)
Mutations of RAS genes are critical events in the pathogenesis of different human tumors and Ras proteins represent a major clinical target for the development of specific inhibitors to use as anticancer agents. Here we present RasGRF1-derived peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce82420a77594c596de71d90e528f47
https://pubmed.ncbi.nlm.nih.gov/21620943
https://pubmed.ncbi.nlm.nih.gov/21620943
Autor:
Yeshasvi Tirupachuri, Prashanth Ramadoss, Lorenzo Rapetti, Claudia Latella, Kourosh Darvish, Silvio Traversaro, Daniele Pucci
Publikováno v:
IEEE Access, Vol 9, Pp 123260-123279 (2021)
Improving the quality of work for human beings is receiving a lot of attention from multiple research communities. In particular, digital transformation in human factors and ergonomics is going to empower the next generation of the socio-technical wo
Externí odkaz:
https://doaj.org/article/c6d93a5a813a461cb942e34774c627f4
Autor:
Silvio Traversa, Rosa Pia Ferrari
Publikováno v:
The Peroxidase Multigene Family of Enzymes ISBN: 9783642635359
Heme peroxidases contain the well-known heme b as prosthetic group and use hydrogen peroxide as electron acceptor to catalyze the oxidation of a large number of substrates [1]. On the basis of sequence homology they can be categorized into two super-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::445d067b564dcf6a7ddb523d19d1a927
https://doi.org/10.1007/978-3-642-58314-8_15
https://doi.org/10.1007/978-3-642-58314-8_15
