Výsledky vyhledávání - "Silvio Buffa"

Biomarkers for vascular ageing in aorta tissues and blood samples

Autor: Eleonora Candi, Gerry Melino, Rita Chiarelli, Davide Borzì, Carmela Rita Balistreri, Floriana Crapanzano, Martina Nania, Fabio Triolo, Giovanni Ruvolo, Anna Maria Lena, Silvio Buffa

Publikováno v: Experimental gerontology. 128

Objectives Functional and quantitative alterations and senescence of circulating and expanded endothelial progenitor cells (EPC), as well as systemic and tissue modifications of angiogenetic and inflammatory molecules, were evaluated for predicting a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98640e415dae908b17b415fc0f9704f9
https://pubmed.ncbi.nlm.nih.gov/31648011

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A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?

Autor: Calogera Pisano, Carmela Rita Balistreri, Giovanni Ruvolo, Giacomo Frati, Antonino G.M. Marullo, Domenico Lio, Giuseppina Colonna-Romano, Sebastiano Sciarretta, Sonia Schiavon, Alberto Allegra, Giuseppe Mazzesi, Ernesto Greco, Elena Cavarretta, Silvio Buffa, Silvia Palmerio

Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)
Oxidative Medicine and Cellular Longevity

Bicuspid valve disease is associated with the development of thoracic aortic aneurysm. The molecular mechanisms underlying this association still need to be clarified. Here, we evaluated the circulating levels of T and B lymphocyte subsets associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec669e44339037586f4b819797e7ca0
http://hdl.handle.net/2108/197165

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Evidence for Less Marked Potential Signs of T-Cell Immunosenescence in Centenarian Offspring Than in the General Age-Matched Population

Autor: Matteo Bulati, Adriana Martorana, Calogero Caruso, Graham Pawelec, Giuseppina Colonna-Romano, David Goldeck, Mariavaleria Pellicanò, Silvio Buffa

Publikováno v: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences; Vol 69

People may reach the upper limits of the human life span at least partly because they have maintained more appropriate immune function, avoiding changes to immunity termed "immunosenescence." Exceptionally long-lived people may be enriched for genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579b3cf81585b78b209cd565d93dbda9
https://doi.org/10.1093/gerona/glt120

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Bone marrow B lymphocytes in multiple myeloma and MGUS: Focus on distribution of naïve cells and memory subsets

Autor: Caterina Giambanco, Francesco Di Bassiano, Silvio Buffa, Calogero Caruso, Matteo Bulati, Giuseppina Colonna Romano, Francesco Gervasi, Fanny Pojero, Alessandra Casuccio

Publikováno v: Leukemia research. 49

Multiple myeloma (MM) is caused by proliferation of clonal plasma cells (cPCs) in bone marrow (BM), associated with numerical and functional defects in immune subsets. An impairment of B cell compartment is involved in onset/progression of the diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a853e5c579d92fb62db9860a09f5ea
https://pubmed.ncbi.nlm.nih.gov/27552680

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Immune profiling of Alzheimer patients

Autor: Calogero Caruso, Graham Pawelec, David Goldeck, Anis Larbi, Giuseppina Colonna-Romano, Silvio Buffa, Matteo Bulati, Graziella Rubino, Evelyna Derhovanessian, Francesco Iemolo, Giuseppina Candore, Mariavaleria Pellicanò

Publikováno v: Journal of Neuroimmunology. 242:52-59

Alzheimer's disease (AD) is characterized by extracellular senile plaques in the brain, containing amyloid-β peptide (Aβ). We identify immunological differences between AD patients and age-matched controls greater than those related to age itself.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be29b97985adc798d22eab654dcc7f1
https://doi.org/10.1016/j.jneuroim.2011.11.005

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Systemic Immune Responses in Alzheimer's Disease: In Vitro Mononuclear Cell Activation and Cytokine Production

Autor: Matteo Bulati, Anna Di Prima, Sonya Vasto, Mario Barbagallo, Mariavaleria Pellicanò, Silvio Buffa, Marta Di Carlo, Calogero Caruso, Gabriella Misiano, Domenico Lio, Pasquale Picone, Domenico Nuzzo, Giuseppina Colonna-Romano, Giuseppina Candore

Publikováno v: Journal of Alzheimer's Disease. 21:181-192

To investigate the systemic signs of immune-inflammatory responses in Alzheimer's disease (AD), in the present study we have analyzed blood lymphocyte subsets and the expression of activation markers on peripheral blood mononuclear cells (PBMCs) from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8338c5c98a1818a89e76dd6ccea1acb2
https://doi.org/10.3233/jad-2010-091714

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B Cells Compartment in Centenarian Offspring and Old People

Autor: Giuseppina Colonna-Romano, Matteo Bulati, Mariavaleria Pellicanò, Sonya Vasto, Domenico Lio, Calogero Caruso, Silvio Buffa, Giuseppina Candore

Publikováno v: Current Pharmaceutical Design. 16:604-608

Immunosenescence is considered a major contributory factor to the increased frequency of morbidity and mortality among elderly. On the other hand centenarians are considered the best example of successful ageing. To gain insight into mechanisms of im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca29de863bdb314e2d063b7b5ba21c7a
https://doi.org/10.2174/138161210790883750

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Are Endothelial Progenitor Cells the Real Solution for Cardiovascular Diseases? Focus on Controversies and Perspectives

Autor: Giovanni Ruvolo, Giuseppe Mazzesi, Domenico Lio, Calogera Pisano, Carmela Rita Balistreri, Silvio Buffa

Publikováno v: BioMed Research International, Vol 2015 (2015)
BioMed Research International

Advanced knowledge in the field of stem cell biology and their ability to provide a cue for counteracting several diseases are leading numerous researchers to focus their attention on “regenerative medicine” as possible solutions for cardiovascul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df181e186a430c405a48b8949241365f
http://hdl.handle.net/10447/144820

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Double Negative (IgG+IgD-CD27-) B Cells are Increased in a Cohort of Moderate-Severe Alzheimer’s Disease Patients and Show a Pro-Inflammatory Trafficking Receptor Phenotype

Autor: Matteo Bulati, Francesco Gervasi, Giuseppina Colonna-Romano, Calogero Caruso, Silvio Buffa, Delia Azzarello, Cecilia Camarda, Roberto Monastero, Adriana Martorana

Alzheimer's disease (AD) is a progressive, irreversible, and debilitating disease for which no effective preventive or disease modifying therapies or treatments have so far been detected. The crucial step in AD pathogenesis is the production of amylo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf760eb4430a6dc4001c122c35b66486
http://hdl.handle.net/10447/102467

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Trafficking phenotype and production of granzyme B by double negative B cells (IgG(+)IgD(-)CD27(-)) in the elderly

Autor: Calogero Caruso, Giuseppina Colonna-Romano, Matteo Bulati, Adriana Martorana, Domenico Lio, Silvio Buffa, Giuseppina Candore

The impairment of humoral immune response in elderly humans has been extensively demonstrated. We have reported the increase of memory B cells (IgG(+)IgD(-)CD27(-), double negative, DN) population in the elderly, in which there is also a typical infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a65b0db1cf474cbb431552e2b254c0
http://hdl.handle.net/10447/99754

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