Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Silvina Mariela Grioli"'
Autor:
María Julia Ferronato, Mario Alfredo Quevedo, Alejandro Carlos Curino, Eliana Noelia Alonso, Santiago Armando Stabile, Evangelina Mascaró, Gabriel Radivoy, Maria Marta Facchinetti, Silvina Mariela Grioli, Cristian Vitale
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 17(3)
Background:1α,25-dihydroxy vitamin D3 (calcitriol) shows potent growth-inhibitory properties on different cancer cell lines, but its hypercalcemic effects have severely hampered its therapeutic application. Therefore, it is important to develop synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505b0d91a6f4320d41be472d9dbc9252
https://pubmed.ncbi.nlm.nih.gov/32819231
https://pubmed.ncbi.nlm.nih.gov/32819231
Autor:
Yagamare Fall, Diego Javier Obiol, Generosa Gómez, Eliana Noelia Alonso, Maria Marta Facchinetti, Mario Alfredo Quevedo, María Julia Ferronato, Andrea Martínez, Silvina Mariela Grioli, Alejandro Carlos Curino
The active form of vitamin D3, calcitriol, is a potent antiproliferative compound. However, when effective antitumor doses of calcitriol are used, hypercalcemic effects are observed, thus blocking its therapeutic application. To overcome this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0125fb5e0309b464d55547d1a0972b62
Wiley Online Library
Wiley Online Library
Autor:
Diego Javier Obiol, Marilina Mascaró, Silvina Mariela Grioli, Yagamare Fall, Maria Marta Facchinetti, Marcos L. Rivadulla, Mario Alfredo Quevedo, Eliana Noelia Alonso, Generosa Gómez, María Julia Ferronato, Andrea Martínez, Josefina Alejandra Guevara, Alejandro Carlos Curino
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Calcitriol analogs have shown promising potential as compounds to be used in cancer chemotherapy. This report presents the synthesis of a novel vitamin D3 derivative with an amide and a carboxyl group in its side chain, called ML-344. In addition, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c97675fbfa6485a43daa71c6d7d2462
https://pubmed.ncbi.nlm.nih.gov/30125657
https://pubmed.ncbi.nlm.nih.gov/30125657
Autor:
María Julia Ferronato, Alejandro Carlos Curino, Débora Gisele Salomón, Evangelina Mascaro, Gabriel Radivoy, Silvina Mariela Grioli, Maria Marta Facchinetti, Cristian Vitale
Publikováno v:
Current Topics in Medicinal Chemistry. 14:2408-2423
The active metabolite of vitamin D, 1α, 25 dihydroxyvitamin D 3 (calcitriol) is classically known to regulate calcium and phosphate homeostasis and bone mineralization. In addition, calcitriol has also been documented to act as a potent anticancer a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cd20aaa82b5d0b54bb025a1667a8be1
https://doi.org/10.2174/1568026615666141208101418
https://doi.org/10.2174/1568026615666141208101418
Autor:
Manuel Pérez, Cristian Vitale, Maximiliano Buschiazzo, Silvina Mariela Grioli, Débora Gisele Salomón, Gabriel Radivoy, Maria Marta Facchinetti, Enrique A. Mesri, Yagamare Fall, Alejandro Carlos Curino, Evangelina Mascaró
Here, we describe the design and synthesis of diethyl [(5Z,7E)-(1S,3R)-1,3-dihydroxy-9,10-secochola-5,7,10(19)-trien-23-in-24-yl] phosphonate (compound 10), which combines the low calcemic properties of phosphonates with the decreased metabolic inact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c544644336023a08b7e3ec33cbbd46
https://europepmc.org/articles/PMC4018101/
https://europepmc.org/articles/PMC4018101/