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Autor:
Madeleine Breshears, Iden A. Sapse, Swapan S. Jain, Craig M. Anderson, Silvie H. Lundgren, Abigail K. Freer, Kyan Jain, Hang Hoang
Publikováno v:
Chemical communications (Cambridge, England). 54(65)
IT127 is a dinuclear transition metal complex that contains a Pt(II) and a Ru(III) metal center. We have shown that IT127 is significantly more effective in binding the 29-base sarcin ricin loop (SRL) RNA in comparison to Cisplatin, a hallmark antica