Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Silviana Lee"'
Autor:
Ke Cong, Nathan MacGilvary, Silviana Lee, Shannon G. MacLeod, Jennifer Calvo, Min Peng, Arne Nedergaard Kousholt, Tovah A. Day, Sharon B. Cantor
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The effectiveness of poly (ADP-ribose) polymerase inhibitors (PARPi) in creating single-stranded DNA gaps and inducing sensitivity requires the FANCJ DNA helicase. Yet, how FANCJ relates to PARP1 inhibition or trapping, which contribute to P
Externí odkaz:
https://doaj.org/article/f2a25b0a9e8844edac2e653b074386d2
Autor:
James Duehr, Silviana Lee, Gursewak Singh, Gregory A. Foster, David Krysztof, Susan L. Stramer, Maria C. Bermúdez González, Eva Menichetti, Robert Geretschläger, Christian Gabriel, Viviana Simon, Jean K. Lim, Florian Krammer
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT Recent reports in the scientific literature have suggested that anti-dengue virus (DENV) and anti-West Nile virus (WNV) immunity exacerbates Zika virus (ZIKV) pathogenesis in vitro and in vivo in mouse models. Large populations of immune ind
Externí odkaz:
https://doaj.org/article/9698ef8dc1f74d87b7450f2a0d3ba7f5
Autor:
Eli Rothenberg, Ke Cong, Silviana Lee, Nicholas J. Panzarino, Katherine S. Pawelczak, Neil Johnson, Sumeet Nayak, Min Peng, Arne Nedergaard Kousholt, Pamela S. VanderVere-Carozza, Jos Jonkers, Jennifer A. Calvo, Wei Ting C. Lee, John J. Turchi, John J. Krais, Sharon B. Cantor
Publikováno v:
Mol Cell
Mutations in BRCA1 or BRCA2 (BRCA) is synthetic lethal with poly(ADP-ribose) polymerase inhibitors (PARPi). Lethality is thought to derive from DNA double-stranded breaks (DSBs) necessitating BRCA function in homologous recombination (HR) and/or fork
Autor:
James Duehr, Silviana Lee, Gursewak Singh, Gregory A. Foster, David Krysztof, Susan L. Stramer, Maria C. Bermúdez Gonzúález, Eva Menichetti, Robert Geretschlager, Christian Gabriel, Viviana Simon, Jean K. Lim, Florian Krammer, Marcela F. Pasetti, Anna Durbin, Alan Barrett
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
mSphere, Vol 3, Iss 1, p e00011-18 (2018)
mSphere
mSphere, Vol 3, Iss 1, p e00011-18 (2018)
mSphere
The relationship between serial infections of two different serotypes of dengue virus and more severe disease courses is well-documented in the literature, driven by so-called antibody-dependent enhancement (ADE). Recently, studies have shown the pos
Autor:
Justin J. Frere, Adam Jacobs, Richard Cadagan, Jean K. Lim, Julia A. Brown, Gregory A. Foster, Florian Krammer, Silviana Lee, Gursewak Singh, Kevin W. Hoffman, James Duehr, Anupa Chokola, David E. Krysztof, Susan L. Stramer, Joshua A. Acklin, Adolfo García-Sastre
Publikováno v:
Immunity. 50:751-762.e5
Zika virus (ZIKV) has recently been associated with birth defects and pregnancy loss after maternal infection. Because dengue virus (DENV) and ZIKV co-circulate, understanding the role of antibody-dependent enhancement in the context of pregnancy is