d-Phenylglycine aminotransferase (d-PhgAT) – substrate scope and structural insights of a stereo-inverting biocatalyst used in the preparation of aromatic amino acids

Autor: Dominic J. Campopiano, Silvia De Cesare, Annabel Serpico, Gary J. Loake, M. Kalim Akhtar, Jon Marles-Wright

Publikováno v: Serpico, A, De Cesare, S, Marles-wright, J, Akhtar, M K, Loake, G J & Campopiano, D J 2020, ' d-Phenylglycine aminotransferase (d-PhgAT) – substrate scope and structural insights of a stereo-inverting biocatalyst used in the preparation of aromatic amino acids ', Catalysis Science & Technology . https://doi.org/10.1039/D0CY01391A

Enantiopure amines are key building blocks in the synthesis of many pharmaceuticals, so a route to their production is a current goal for biocatalysis. The stereo-inverting D-phenylglycine aminotransferase (D-PhgAT), isolated from Pseudomonas stutzer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b349103c68c7980399eef4784e385abe
https://doi.org/10.1039/d0cy01391a

Direct monitoring of biocatalytic deacetylation of amino acid substrates by

Autor: Silvia, De Cesare, Catherine A, McKenna, Nicholas, Mulholland, Lorna, Murray, Juraj, Bella, Dominic J, Campopiano

Publikováno v: Organicbiomolecular chemistry. 19(22)

Amino acids are key synthetic building blocks that can be prepared in an enantiopure form by biocatalytic methods. We show that the l-selective ornithine deacetylase ArgE catalyses hydrolysis of a wide-range of N-acyl-amino acid substrates. This acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48882f7f787e7bcd49cc00b57f6b1d7d
https://pubmed.ncbi.nlm.nih.gov/33998641

Values in evolutionary biology: a comparison between the contemporary debate on organic progress and Canguilhem's biological philosophy

Autor: Silvia De Cesare

Publikováno v: History and philosophy of the life sciences. 44(2)

The aim of this paper is to make a comparison and build up a dialogue between two different philosophical approaches to values in evolutionary biology. First, I present the approach proposed by Alexander Rosenberg and Daniel McShea in their contribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb352d2d2b0f2f375754f53e56def504
https://pubmed.ncbi.nlm.nih.gov/35614290

Dietary plasticity in the bivalve Astarte moerchi revealed by a multimarker study in two Arctic fjords

Autor: Laurent Chauvaud, Gesche Winkler, Tarik Meziane, Silvia De Cesare, Frédéric Olivier, Mikael K. Sejr, Joëlle Richard, Julien Thébault

Publikováno v: Marine Ecology Progress Series
Marine Ecology Progress Series, Inter Research, 2017, 567, pp.157-172. ⟨10.3354/meps12035⟩
De Cesare, S, Meziane, T, Chauvaud, L, Richard, J, Sejr, M K, Thebault, J, Winkler, G & Olivier, F 2017, ' Dietary plasticity in the bivalve Astarte moerchi revealed by a multimarker study in two Arctic fjords ', Marine Ecology-Progress Series, vol. 567, pp. 157-172 . https://doi.org/10.3354/meps12035
Marine Ecology Progress Series, 2017, 567, pp.157-172. ⟨10.3354/meps12035⟩
Marine Ecology Progress Series (0171-8630) (Inter-research), 2017-03, Vol. 567, P. 157-172

International audience; Arctic coastal ecosystems are likely to be strongly affected by predicted environmental changes such as sea-ice decline and increase in freshwater input and turbidity. These changes are expected to impact primary production dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1774c9529724bdb19d7d536fffd95daf
https://hal.univ-brest.fr/hal-01510345