Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Silvia Waldeck"'
Autor:
Silvia Waldeck, Jan Mitschke, Sebastian Wiesemann, Michael Rassner, Geoffroy Andrieux, Max Deuter, Jurik Mutter, Anne‐Marie Lüchtenborg, Daniel Kottmann, Laurin Titze, Christoph Zeisel, Martina Jolic, Ulrike Philipp, Silke Lassmann, Peter Bronsert, Christine Greil, Justyna Rawluk, Heiko Becker, Lisa Isbell, Alexandra Müller, Soroush Doostkam, Bernward Passlick, Melanie Börries, Justus Duyster, Julius Wehrle, Florian Scherer, Nikolas von Bubnoff
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 527-537 (2022)
Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in patients with non‐small‐cell lung cancer (NSCLC). However, little is known about its
Externí odkaz:
https://doaj.org/article/4399d10b1bd049f3a353a6cfadf469f6
Autor:
Michael Rassner, Silvia Waldeck, Marie Follo, Stefanie Jilg, Ulrike Philipp, Martina Jolic, Julius Wehrle, Philipp J. Jost, Christian Peschel, Anna Lena Illert, Justus Duyster, Florian Scherer, Nikolas von Bubnoff
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5411 (2023)
Background: Mutations in cKIT or PDGFRA are found in up to 90% of patients with gastrointestinal stromal tumors (GISTs). Previously, we described the design, validation, and clinical performance of a digital droplet (dd)PCR assay panel for the detect
Externí odkaz:
https://doaj.org/article/6eb23afb46f54cd498e8f7c54f9d2070
Autor:
Silvia Waldeck, Michael Rassner, Philip Keye, Marie Follo, Dieter Herchenbach, Cornelia Endres, Anne Charlet, Geoffroy Andrieux, Ulrich Salzer, Melanie Boerries, Justus Duyster, Nikolas vonBubnoff
Publikováno v:
Molecular Oncology, Vol 14, Iss 4, Pp 779-794 (2020)
FLT3‐ITD tyrosine kinase inhibitors (TKI) show limited clinical activity in acute myeloid leukemia (AML) due to emerging resistance. TKI resistance is mediated by secondary FLT3‐ITD mutations only in a minority of cases. We hypothesize that the c
Externí odkaz:
https://doaj.org/article/bd63d97f309d4829be7c3c0875737bfc
Autor:
Julius Wehrle, Ulrike Philipp, Martina Jolic, Marie Follo, Saskia Hussung, Silvia Waldeck, Max Deuter, Michael Rassner, Jan Braune, Justyna Rawluk, Christine Greil, Cornelius F. Waller, Heiko Becker, Jesús Duque-Afonso, Anna L. Illert, Ralph M. Fritsch, Frank Meiss, Justus Duyster, Nikolas von Bubnoff, Florian Scherer
Publikováno v:
Diagnostics, Vol 10, Iss 8, p 550 (2020)
Background: Circulating tumor DNA (ctDNA) in the blood plasma of cancer patients is an emerging biomarker used across oncology, facilitating noninvasive disease monitoring and genetic profiling at various disease milestones. Digital droplet PCR (ddPC
Externí odkaz:
https://doaj.org/article/e63030888c5d4ece9ce2c4dc54ca2dd8
Autor:
Lisa Kristina Isbell, Cordula Tschuch, Soroush Doostkam, Silvia Waldeck, Geoffroy Andrieux, Khalid Shoumariyeh, Dorothee Lenhard, Hans Eckart Schaefer, Peter Christoph Reinacher, Ingrid Bartsch, Milena Pantic, Janaki Manoja Vinnakota, Vinodh Kakkassery, Elisabeth Schorb, Florian Scherer, Anna Verena Frey, Melanie Boerries, Gerald Illerhaus, Justus Duyster, Julia Schueler, Nikolas von Bubnoff
Aims: How and why lymphoma cells home to the central nervous system and vitreoretinal compartment in primary diffuse large B-cell lymphoma of the central nervous system remain unknown. Our aim was to create an in vivo model to study lymphoma cell tro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a847c7487053c2c39ec80d091bb8fd
https://publica.fraunhofer.de/handle/publica/442755
https://publica.fraunhofer.de/handle/publica/442755
Autor:
Justyna Rawluk, Anne-Marie Lüchtenborg, Peter Bronsert, Julius Wehrle, Nikolas von Bubnoff, Martina Jolic, Alexandra Müller, Jan Mitschke, Silvia Waldeck, Melanie Börries, Justus Duyster, Soroush Doostkam, Laurin Titze, Heiko Becker, Christoph Zeisel, Sebastian Wiesemann, Silke Lassmann, Max Deuter, Daniel Kottmann, Florian Scherer, Jurik Mutter, Ulrike Philipp, Bernward Passlick, Lisa K. Isbell, Geoffroy Andrieux, Michael Rassner, Christine Greil
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 527-537 (2022)
Molecular Oncology
Molecular Oncology
Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in patients with non‐small‐cell lung cancer (NSCLC). However, little is known about its
Autor:
Melanie Boerries, Geoffroy Andrieux, Ulrich Salzer, Michael Rassner, Silvia Waldeck, Nikolas von Bubnoff, Anne Charlet, Dieter Herchenbach, Justus Duyster, Cornelia Endres, Philip Keye, Marie Follo
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 4, Pp 779-794 (2020)
Molecular Oncology, Vol 14, Iss 4, Pp 779-794 (2020)
FLT3‐ITD tyrosine kinase inhibitors (TKI) show limited clinical activity in acute myeloid leukemia (AML) due to emerging resistance. TKI resistance is mediated by secondary FLT3‐ITD mutations only in a minority of cases. We hypothesize that the c
Autor:
Silvia Waldeck, Philipp J. Jost, Victoria Kehl, Christian Peschel, Stefanie Jilg, Peter Hohenberger, Ulrike Philipp, Jacqueline Maier, Sebastian Bauer, Nikolas von Bubnoff, Justus Duyster, Timo Gaiser, Jan Mitschke, Thoralf Lange, Andreas Sauter, Marie Follo, Katja Specht, Michael Rassner
Publikováno v:
International Journal of Cancer. 145:2292-2303
This prospective trial aimed to investigate whether tumor-specific cKIT and PDGFRA mutations can be detected and quantified in circulating tumor (ct)DNA in patients with active GIST, and whether detection indicates disease activity. We included 25 pa
Autor:
Gerald Gitsch, Lucas Willmann, Marc Hirschfeld, Elmar Stickeler, Silvia Waldeck, M Jäger, Gerta Rücker, Thalia Erbes, Bernd Kammerer, Sebastian Mayer
Publikováno v:
International Journal of Hyperthermia. 32:630-642
Purpose: Expression profile alterations of nine breast cancer (BC)-associated secreted microRNAs (miRs) were determined under microenvironmental alterations occurring in tumour progression, metastasis or specific oncological treatment modalities. The
Autor:
Florian Scherer, Ulrike Philipp, Julius Wehrle, Christine Greil, Jesus Duque-Afonso, Marie Follo, Jan Braune, Max Deuter, Cornelius F. Waller, Frank Meiss, Anna Lena Illert, Ralph Fritsch, Justyna Rawluk, Michael Rassner, Martina Jolic, Nikolas von Bubnoff, Heiko Becker, Saskia Hussung, Justus Duyster, Silvia Waldeck
Publikováno v:
Diagnostics
Volume 10
Issue 8
Diagnostics, Vol 10, Iss 550, p 550 (2020)
Volume 10
Issue 8
Diagnostics, Vol 10, Iss 550, p 550 (2020)
Background: Circulating tumor DNA (ctDNA) in the blood plasma of cancer patients is an emerging biomarker used across oncology, facilitating noninvasive disease monitoring and genetic profiling at various disease milestones. Digital droplet PCR (ddPC