Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Silvia Viaggi"'
Autor:
Elisa Tassano, Sara Uccella, Patrizia Ronchetto, Joana Soraia Martinheira Da Silva, Silvia Viaggi, Margherita Mancardi, Luca Ramenghi, Alessandra Murri, Marina Biondi, Giorgio Gimelli, Cristina Morerio, Michela Malacarne, Domenico Coviello
Publikováno v:
Cytogenetic and Genome Research. 162:132-139
Interstitial 2q24.2q24.3 microdeletions are rare cytogenetic aberrations associated with heterogeneous clinical features depending on the size of the deletion. Here, we describe 2 patients with overlapping de novo 2q24.2q24.3 deletions, characterized
Autor:
Rute Luísa Cabrita Pinto, Silvia Viaggi, Edoardo Canale, Marina Martinez Popple, Valeria Capra, Giuseppina Conteduca, Barbara Testa, Domenico Coviello, Angela Elvira Covone
Publikováno v:
Genes. 14:810
The CC2D2A gene is essential for primary cilia formation, and its disruption has been associated with Joubert Syndrome-9 (JBTS9), a ciliopathy with typical neurodevelopmental features. Here, we describe an Italian pediatric patient with typical featu
Autor:
Francesca Piaggio, Michela Croce, Francesco Reggiani, Paola Monti, Cinzia Bernardi, Marianna Ambrosio, Barbara Banelli, Mehmet Dogrusöz, Ralf Jockers, Domenico Bordo, Roberto Puzone, Silvia Viaggi, Domenico Coviello, Francesco B. Lanza, Martina Bartolucci, Andrea Petretto, Carlo Mosci, Rosaria Gangemi, Pieter A. van der Velden, Martine J. Jager, Ulrich Pfeffer, Adriana Amaro
Publikováno v:
European Journal of Cancer, 170, 27-41. ELSEVIER SCI LTD
Background and aim of the study: Mutations in the G alpha-genes GNAQ and GNA11 are found in 85-90% of uveal melanomas (UM). Aim of the study is to understand whether the mutations in both genes differentially affect tumor characteristics and outcome
Autor:
Armin R. Afshar, Martine J. Jager, Helen Kalirai, Emine Kilic, Azzam Taktak, Natasha M. van Poppelen, Nikolaos E. Bechrakis, Rudolf F. Guthoff, Heinrich Heimann, Antonio Eleuteri, Sarah E. Coupland, Bertil Damato, Norbert Bornfeld, Claudia H. D. Le Guin, Laura J. Bonnett, Gregorius P M Luyten, Alexander Tsygankov, Vinodh Kakkassery, Carlo Mosci, Matthew Traynor, Mehmet Dogrusöz, Rumana Hussain, Silvia Viaggi, Paolo Ligorio, Marina Marinkovic, Christopher J. Hill, S.V. Saakyan, Björn O Scheef, Kyra N Smit, Alda Cunha Rola, Annelies de Klein
Publikováno v:
CANCERS
Cancers, Vol 12, Iss 2, p 477 (2020)
Cancers
Volume 12
Issue 2
Cancers, 12(2). MDPI
Cancers, 12. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, Vol 12, Iss 2, p 477 (2020)
Cancers
Volume 12
Issue 2
Cancers, 12(2). MDPI
Cancers, 12. Multidisciplinary Digital Publishing Institute (MDPI)
Uveal melanoma (UM) is fatal in ~50% of patients as a result of disseminated disease. This study aims to externally validate the Liverpool Uveal Melanoma Prognosticator Online V3 (LUMPO3) to determine its reliability in predicting survival after trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06d3106e1b55869592804a0e4b2450a
https://hdl.handle.net/1887/3182910
https://hdl.handle.net/1887/3182910
Autor:
D. A. Coviello, Ulrich Pfeffer, Alessandra Eva, Cinzia Bernardi, Francesca Piaggio, Roberto Puzone, Adriana Amaro, Michela Croce, Michael Zeschnigk, Silvia Viaggi, Annalisa Barla, Davide Cangelosi, Pieter A. van der Velden, Veronica Tozzo, Martine J. Jager, Serena Patrone
Publikováno v:
Cancers, 11(11)
Cancers
Cancers, Vol 11, Iss 11, p 1688 (2019)
Volume 11
Issue 11
Cancers
Cancers, Vol 11, Iss 11, p 1688 (2019)
Volume 11
Issue 11
Background: Uveal melanoma (UM), a rare cancer of the eye, is characterized by initiating mutations in the genes G-protein subunit alpha Q (GNAQ), G-protein subunit alpha 11 (GNA11), cysteinyl leukotriene receptor 2 (CYSLTR2), and phospholipase C bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a59ad0403ffaca9e1adbe3cebeea768
http://hdl.handle.net/1887/121228
http://hdl.handle.net/1887/121228
Autor:
Matteo Puntoni, Mauro Castagnetta, Giovanna Angelini, Carlotta Defferrari, Urlich Pfeffer, Paolo Ligorio, Massimo Romani, Barbara Banelli, Francesco Lanza, Domenico A. Coviello, Andrea Decensi, Carlo Mosci, Irena Maric, Mariangela Rutigliani, Silvia Viaggi, Serena Patrone, Adriana Amaro, Silvia Rancati, Roberto Bandelloni
Publikováno v:
Genes, Chromosomes and Cancer. 57:387-400
Uveal melanoma (UM) exhibits recurring chromosomal abnormalities and gene driver mutations, which are related to tumor evolution/progression. Almost half of the patients with UM develop distant metastases, predominantly to the liver, and so far there
Autor:
Paola Queirolo, Ulrich Pfeffer, Francesco Lanza, Paola Visconti, Roberto Puzone, Federica Parodi, Carlo Mosci, Anna Morabito, Maria Pia Pistillo, Luca Anselmi, Marina Gualco, Michael Zeschnigk, Federica Raggi, Mario Mandalà, Konrad Diedrich, Maria Carla Bosco, Irena Maric, Laura Spano, Domenico A. Coviello, Adriana Amaro, Silvia Viaggi, Giovanna Angelini, Luigi Varesio, Paola Ghiorzo, Cornelia Götz
Importance Chromosome 6p amplification is associated with more benign behavior for uveal melanomas (UMs) with an otherwise high risk of metastasis conferred by chromosome 3 monosomy. Chromosome 6p contains several members of the B7 family of immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c08ed17299ddb12c2b6ab1b807d6a07
http://hdl.handle.net/11391/1480974
http://hdl.handle.net/11391/1480974
Publikováno v:
FEBS Journal. 279:2479-2494
Fanconi's anemia (FA) patients face severe pathological consequences. Bone marrow failure, the major cause of death in FA, accounting for as much as 80-90% of FA mortality, appears to be significantly linked to excessive apoptosis of hematopoietic ce
Publikováno v:
Chromosome Research. 19:37-231
Autor:
M.G. Grimoldi, Eugenio Erba, Annalisa Zunino, Maria Teresa Bardella, Luisa Doneda, Elena Dogliotti, Luca Elli, Silvia Viaggi, Leda Roncoroni
Publikováno v:
Cancer Investigation. 28:7-12
The aim of the study was to investigate whether changes in the pattern of gene copy number and cell cycle were present passing from the two- to the three-dimensional cell culture system. We used three human colon adenocarcinoma cell lines grown two-