Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Silvia Tortola"'
Publikováno v:
Journal of Biological Chemistry. 282:5075-5084
In mammalian cells, multiple stimuli induce the expression of the immediate early gene c-fos. The specificity of c-fos transcriptional response depends on the activation of signaling protein kinases, transcription factors, and chromatin-modifying com
Publikováno v:
Nucleic Acids Research
MAP kinase phosphatase-1 (MKP-1) controls nuclear MAP kinase activity with important consequences on cell growth or apoptosis. MKP-1 transcription is initiated constitutively but elongation is blocked within exon 1. It is unclear how induction of MKP
Publikováno v:
Journal of Biological Chemistry. 276:33319-33327
Transcriptional elongation of many eukaryotic, prokaryotic, and viral genes is tightly controlled, which contributes to gene regulation. Here we describe this phenomenon for the MAP kinase phosphatase 1 (MKP-1) immediate early gene. In rat GH4C1 pitu
Publikováno v:
Journal of receptor and signal transduction research. 22(1-4)
Long-term cellular processes like proliferation, differentiation, and adaptive responses (e.g. neuronal plasticity) are initiated by the synthesis of immediate early gene (IEG) products which control the expression of late response genes. Immediate e
Autor:
M. A. Reymond, Bettina Borisch, R Steinert, Vincent Olivier Ott, Silvia Tortola, K Guenther, Werner Schlegel
Publikováno v:
The Pharmacogenomics Journal, Vol. 1, No 2 (2001) pp. 142-51
Two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) is increasingly used for target discovery in human disease to complement genomic studies. We have assessed the possibilities and limits of 2-D PAGE applied to human colorectal cancer. Up t
Autor:
Marc A. Reymond, Hans Lippert, Werner Schlegel, Miguel A. Peinado, Peter Stosiek, Ralf Steinert, M. Hantschick, Silvia Tortola, Ingo Gastinger
Publikováno v:
Europe PubMed Central
PURPOSE: To study bone marrow micrometastases from colorectal cancer patients for the presence of K-ras mutations and to compare their genotype with that of the corresponding primary tumor. PATIENTS AND METHODS: Bilateral iliac crest aspiration was p
Autor:
Miguel A. Peinado, Marc A. Reymond, Denis F. Hochstrasser, Graham J. Hughes, J Riese, Thomas Kirchner, Jean-Charles Sanchez, Klaus Günther, Ferdinand Köckerling, Silvia Tortola, Werner Hohenberger
Publikováno v:
Electrophoresis. 18(15)
New diagnostic and prognostic markers are needed in colorectal cancer. They can be found by differential analysis at DNA, RNA or protein level. The accuracy of phenotypic comparisons of tumor and normal tissues depends on the purity of the samples. W
Autor:
Claus Schneider, Jean-Charles Sanchez, Ferdinand Köckerling, Werner Hohenberger, Peter Rohwer, Denis F. Hochstrasser, Silvia Tortola, Marc A. Reymond, Thomas Kirchner
Publikováno v:
Electrophoresis. 18(3-4)
Large tissue samples from ten patients operated for colorectal cancer were prepared in the operating room in iced phosphate buffered saline, containing ethylene diaminetetraacetic acid and protease inhibitors. After cutting the specimens into small f
Publikováno v:
International Archives of Integrated Medicine. Dec2017, Vol. 4 Issue 12, p168-184. 17p. 14 Color Photographs, 13 Charts, 5 Graphs.
Publikováno v:
Journal of Receptors & Signal Transduction; Nov2002, Vol. 22 Issue 1-4, p17-29, 13p, 1 Map