Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Silvia Tognetti"'
Autor:
Ya-Lan Chang, Shun-Fu Tseng, Yu-Ching Huang, Zih-Jie Shen, Pang-Hung Hsu, Meng-Hsun Hsieh, Chia-Wei Yang, Silvia Tognetti, Berta Canal, Laia Subirana, Chien-Wei Wang, Hsiao-Tan Chen, Chi-Ying Lin, Francesc Posas, Shu-Chun Teng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
A G1 cell cycle regulatory kinase Cip1 has been identified in budding yeast but how this is regulated is unclear. Here the authors identify cell cycle (Mcm1) and stress-mediated (Msn 2/4) transcription factors as regulating Cip1, causing stress induc
Externí odkaz:
https://doaj.org/article/471f7f9a1954498791ddcc5b39f8dc56
Autor:
Christian Linke, Anastasia Chasapi, Alberto González-Novo, Istabrak Al Sawad, Silvia Tognetti, Edda Klipp, Mart Loog, Sylvia Krobitsch, Francesc Posas, Ioannis Xenarios, Matteo Barberis
Publikováno v:
npj Systems Biology and Applications, Vol 3, Iss 1, Pp 1-12 (2017)
Cell cycle control: Order in time achieved by dynamic coupling A dynamic coupling of cyclin-dependent kinase with transcription factors in yeast offers insights into the timely cell cycle progression. An international team lead by Matteo Barberis fro
Externí odkaz:
https://doaj.org/article/b97661edfbb74ad691b7c34f9005b5f8
Autor:
Ethel Queralt, Javier Jiménez, Alba Duch, Silvia Tognetti, Eulàlia de Nadal, Francesc Posas, Matteo Viganò
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Proceedings of the National Academy of Sciences of the United States of America
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Proceedings of the National Academy of Sciences of the United States of America
10 páginas, 5 figuras
Adaptation to environmental changes is crucial for cell fitness. In Saccharomyces cerevisiae, variations in external osmolarity trigger the activation of the stress-activated protein kinase Hog1 (high-osmolarity glycerol 1
Adaptation to environmental changes is crucial for cell fitness. In Saccharomyces cerevisiae, variations in external osmolarity trigger the activation of the stress-activated protein kinase Hog1 (high-osmolarity glycerol 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5be05df4d0c7af83f72c723eee73c4
http://hdl.handle.net/10261/272271
http://hdl.handle.net/10261/272271
Autor:
Samuel T. Fatoba, Elisabetta Leo, Yves Pommier, Claire M. Mulvey, Andrei L. Okorokov, Silvia Tognetti, Melissa Berto, Jasminka Godovac-Zimmermann
Publikováno v:
Nucleic Acids Research
The eukaryotic DNA replication initiation factor Mcm10 is essential for both replisome assembly and function. Human Mcm10 has two DNA-binding domains, the conserved internal domain (ID) and the C-terminal domain (CTD), which is specific to metazoans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43efd141b827df8690c3bb46dc3a9268
https://doi.org/10.1093/nar/gkt131
https://doi.org/10.1093/nar/gkt131
Autor:
Silvia Tognetti, Christian Speck
Publikováno v:
Nature cell biology
Half of human genome is made of repetitive DNA. However, mechanisms underlying replication of chromosome regions containing repetitive DNA are poorly understood. We reconstituted replication of defined human chromosome segments using Bacterial Artifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cedf2c1c4994db2bb69d0f9bac2ff6
https://pubmed.ncbi.nlm.nih.gov/27111843
https://pubmed.ncbi.nlm.nih.gov/27111843
Autor:
Jingchuan Sun, Zuanning Yuan, Silvia Tognetti, Christian Speck, Bruce Stillman, Alberto Riera, Alejandra Fernández-Cid, Huilin Li
Publikováno v:
Genesdevelopment. 28(20)
Eukaryotic cells license each DNA replication origin during G1 phase by assembling a prereplication complex that contains a Mcm2–7 (minichromosome maintenance proteins 2–7) double hexamer. During S phase, each Mcm2–7 hexamer forms the core of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db18cabe8db1cf0e465db5c208db53b1
https://pubmed.ncbi.nlm.nih.gov/25319829
https://pubmed.ncbi.nlm.nih.gov/25319829
Autor:
Silvia Tognetti, Christian Speck, Nicola Silva, Nuria Ferrandiz, James W. Lightfoot, Enrique Martinez-Perez, Andre Furger, Ambrosius P. Snijders, Vesela Encheva, Oana Telecan, Simon Hanni, Consuelo Barroso, Peter Faull
Publikováno v:
Developmental Cell
© 2014 Elsevier Inc.Proper chromosome segregation during meiosis requires the assembly of the synaptonemal complex (SC) between homologous chromosomes. However, the SC structure itself is indifferent to homology, andpoorly understood mechanisms that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639556efafcd4176ae40ea6dcd7e13e2
http://hdl.handle.net/10044/1/27321
http://hdl.handle.net/10044/1/27321
© 2014, Springer-Verlag Berlin Heidelberg.A crucial step during eukaryotic initiation of DNA replication is the correct loading and activation of the replicative DNA helicase, which ensures that each replication origin fires only once. Unregulated D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be9ef3fd1990db547e7e14993b03a3d
http://hdl.handle.net/10044/1/27085
http://hdl.handle.net/10044/1/27085
Autor:
M. Carmen Herrera, Alberto Riera, Christian Speck, Alejandra Fernández-Cid, Stefan A. Samel, Huilin Li, Silvia Tognetti, Jingchuan Sun
The regulated loading of the replicative helicase minichromosome maintenance proteins 2–7 (MCM2–7) onto replication origins is a prerequisite for replication fork establishment and genomic stability. Origin recognition complex (ORC), Cdc6, and Cd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e1ae95907ec99e66b0368150f68ab9
http://hdl.handle.net/10044/1/15414
http://hdl.handle.net/10044/1/15414
Publikováno v:
Seminars in celldevelopmental biology. 30
A central step in eukaryotic initiation of DNA replication is the loading of the helicase at replication origins, misregulation of this reaction leads to DNA damage and genome instability. Here we discuss how the helicase becomes recruited to origins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3098148af96381c8da01e90b1594d16
https://pubmed.ncbi.nlm.nih.gov/24637008
https://pubmed.ncbi.nlm.nih.gov/24637008