Výsledky vyhledávání - "Silvia Tamborero"

Akademický článek

Transmembrane but not soluble helices fold inside the ribosome tunnel

Autor: Manuel Bañó-Polo, Carlos Baeza-Delgado, Silvia Tamborero, Anthony Hazel, Brayan Grau, IngMarie Nilsson, Paul Whitley, James C. Gumbart, Gunnar von Heijne, Ismael Mingarro

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)

Integral membrane proteins are assembled into the ER membrane via the ribosome-translocon channel. Here authors use in vitro translation assays and MD simulations to show that folding in the ribosome is favorable for TM helices, but unfavorable for s

Externí odkaz: https://doaj.org/article/3c5b89887b174ab79e5d3eb70d8006cc

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N-glycosylation efficiency is determined by the distance to the C-terminus and the amino acid preceding an Asn-Ser-Thr sequon

Autor: Silvia Tamborero, Marc A. Marti-Renom, Ismael Mingarro, Manuel Bañó-Polo, Francesca Baldin

Publikováno v: Protein Science. 20:179-186

N-glycosylation is the most common and versatile protein modification. In eukaryotic cells, this modification is catalyzed cotranslationally by the enzyme oligosaccharyltransferase, which targets the β-amide of the asparagine in an Asn-Xaa-Ser/Thr c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dd05a49bcd477677ca26f6fdfa5df44
https://doi.org/10.1002/pro.551

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Membrane topology of gp41 and amyloid precursor protein: Interfering transmembrane interactions as potential targets for HIV and Alzheimer treatment

Autor: Luis Martínez-Gil, Concepción Abad, Silvia Tamborero, Ismael Mingarro

Publikováno v: Biochimica et Biophysica Acta. Biomembranes
Abad Mazario, Concepción Martínez Gil, Luis Tamborero Capilla, Silvia Mingarro Muñoz, Ismael 2009 Membrane topology of gp41 and amyloid precursor protein: interfering transmembrane interactions as potential targets for HIV and Alzheimer treatment Biochimica et Biophysica Acta-Biomembranes 1788 10 2132 2141
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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The amyloid precursor protein (APP), that plays a critical role in the development of senile plaques in Alzheimer disease (AD), and the gp41 envelope protein of the human immunodeficiency virus (HIV), the causative agent of the acquired immunodeficie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a8268a57f8aa19179c97415857ae1c

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Design of a minimized cyclic tetrapeptide that neutralizes bacterial endotoxins

Autor: Silvia Tamborero, Enrique Pérez-Payá, Fernando Albericio, Puig Mora, Luis J. Cruz, Carlos Mas-Moruno

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
Universitat Jaume I

Septic shock is a leading cause of mortality in intensive care patients, and no specific drugs are as yet available for its treatment. Therefore, new leads ar e required in order to increase the numbe r of active molecules that may develop into effic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bc91f9cdf7bb4ce5fb31ef67fb37be
https://doi.org/10.1002/psc.755

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The Tobacco mosaic virus movement protein associates with but does not integrate into biological membranes

Autor: Silvia Tamborero, Luis Martínez-Gil, Ismael Mingarro, Vicente Pallás, Jesús A. Sánchez-Navarro, Ana M. Peiró

Publikováno v: Peiró, Ana Martínez Gil, Luis Tamborero Capilla, Silvia Pallás Benet, Vicente Sánchez Navarro, Jesús A. Mingarro Muñoz, Ismael 2014 The Tobacco mosaic virus movement protein associates with but does not integrate into biological membranes Journal of Virology 88 5 3016 3026
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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RODERIC. Repositorio Institucional de la Universitat de Valéncia

Plant positive-strand RNA viruses require association with plant cell endomembranes for viral translation and replication, as well as for intra- and intercellular movement of the viral progeny. The membrane association and RNA binding of the Tobacco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc918905f76402aef16d305e9da8bf9
http://hdl.handle.net/10550/54940

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BB0172, a Borrelia burgdorferi Outer Membrane Protein That Binds Integrin Α3Β1

Autor: Elaine Wood, Maria D. Esteve-Gassent, Silvia Tamborero, Ismael Mingarro

Publikováno v: Wood, Elaine Tamborero Capilla, Silvia Mingarro Muñoz, Ismael Esteve Gassent, María Dolores (2013) BB0172, a Borrelia burgdorferi Outer Membrane Protein That Binds Integrin Α3Β1 Journal of Bacteriology 195 15 3320 3330
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

Lyme disease is a multisystemic disorder caused by Borrelia burgdorferi infection. Upon infection, some B. burgdorferi genes are upregulated, including members of the microbial surface components recognizing adhesive matrix molecule (MSCRAMM) protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7d338c2f42591df3f79b22f773f30f

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Membrane insertion and topology of the TRanslocating chain-Associating Membrane protein (TRAM)

Autor: Marçal Vilar, Silvia Tamborero, Ismael Mingarro, Arthur E. Johnson, Luis Martínez-Gil

Publikováno v: Tamborero Capilla, Silvia Vilar, Marçal Martínez Gil, Luis Johnson, Arthur E. Mingarro Muñoz, Ismael 2011 Membrane insertion and topology of the TRanslocating chain-Associating Membrane protein (TRAM) Journal of Molecular Biology 406 4 571 582
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

The translocating chain-associating membrane protein (TRAM) is a glycoprotein involved in the translocation of secreted proteins into the endoplasmic reticulum (ER) lumen and in the insertion of integral membrane proteins into the lipid bilayer. As a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a5e9f76ed527db7fb6e195221ab457
http://hdl.handle.net/10550/56203

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N-glycosylation efficiency is determined by the distance to the C-terminus and the amino acid preceding an Asn-Ser-Thr sequon

Autor: Manuel, Bañó-Polo, Francesca, Baldin, Silvia, Tamborero, Marc A, Marti-Renom, Ismael, Mingarro

Publikováno v: Protein science : a publication of the Protein Society. 20(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4738d6185b1e152964ce88d98b018bb
https://pubmed.ncbi.nlm.nih.gov/21082725

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Viral membrane protein topology is dictated by multiple determinants in its sequence

Autor: Arthur E. Johnson, Ana Saurí, Ismael Mingarro, Luis Martínez-Gil, Silvia Tamborero

Publikováno v: Journal of molecular biology. 387(1)

The targeting, insertion, and topology of membrane proteins have been extensively studied in both prokaryotes and eukaryotes. However, the mechanisms used by viral membrane proteins to generate the correct topology within cellular membranes are less

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d0f0be1ef0039af34ccc6448614d93
https://pubmed.ncbi.nlm.nih.gov/19302797

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