Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Silvia Taffetani"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 289:C971-C981
Interleukin-6 (IL-6) has been implicated as an autocrine factor involved in growth of several human cancers, such as tumors arising from the biliary tract or cholangiocarcinoma. In malignant biliary tract epithelia, IL-6 activates the p38 MAPK pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b1553c2244bcf57602fb8de68092bf
https://doi.org/10.1152/ajpcell.00081.2005
https://doi.org/10.1152/ajpcell.00081.2005
Autor:
Julie Venter, Heather Francis, Yoshiyuki Ueno, Tushar Patel, Silvia Taffetani, Gianfranco Alpini, Shannon Glaser, Fanyin Meng
Publikováno v:
The American Journal of Pathology. 166:1671-1679
Chronic cholestatic diseases are characterized by morphological changes involving cholangiocyte proliferation and functional alterations of secretory capacity. The plant polyphenol tannic acid inhibits the growth of malignant human cholangiocytes. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fc59eb032e8858466147937ef176e8
https://doi.org/10.1016/s0002-9440(10)62477-7
https://doi.org/10.1016/s0002-9440(10)62477-7
Autor:
Antonio Benedetti, Luca Marucci, Jo Lynne Phinizy, Shannon Glaser, Silvia Taffetani, Barbara Barbaro, Heather Francis, Marco Marzioni, Tania Roskams, Domenico Alvaro, Gene LeSage, Gianfranco Alpini, Yoshiytiki Ueno, Giammarco Fava
Publikováno v:
Hepatology. 40:1116-1127
Acetylcholine potentiates secretin-stimulated ductal secretion by Ca(2+)-calcineurin-mediated modulation of adenylyl cyclase. D2 dopaminergic receptor agonists inhibit secretin-stimulated ductal secretion via activation of protein kinase C (PKC)-gamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a149215230d55a426cd74018dd48f3
https://doi.org/10.1002/hep.20424
https://doi.org/10.1002/hep.20424
Autor:
Gianfranco Alpini, Giammarco Fava, Yoshiyuki Ueno, Jo Lynne Phinizy, Ramona Reichenbach, Marco Marzioni, Domenico Alvaro, Luca Marucci, Heather Francis, Antonio Benedetti, Julie Venter, Silvia Taffetani, Shannon Glaser, Gene LeSage
Publikováno v:
Journal of Hepatology. 41:528-537
Background/Aims To evaluate if increased cholangiocyte cAMP levels alone are sufficient to enhance cholangiocyte proliferation and secretion. Methods Normal rats were treated in vivo with forskolin for two weeks. Cholangiocyte apoptosis, proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed5bfac4e03e57d4817844e2f05207f
https://doi.org/10.1016/j.jhep.2004.06.009
https://doi.org/10.1016/j.jhep.2004.06.009
Autor:
Jo Lynne Phinizy, Gene LeSage, Noriatsu Kanno, Gianfranco Alpini, Shannon Glaser, Silvia Taffetani, Heather Francis
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 286:G973-G982
Tauroursodeoxychate (TUDCA) is used for the treatment of cholangiopathies including primary sclerosing cholangitis, which is considered the primary risk factor for cholangiocarcinoma. The effect of TUDCA on cholangiocarcinoma growth is unknown. We ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43253f01b62f473b8fe2d652656c86d0
https://doi.org/10.1152/ajpgi.00270.2003
https://doi.org/10.1152/ajpgi.00270.2003
Autor:
Antonio Di Sario, Marco Marzioni, Antonio Benedetti, Paola Pigini, Cinzia Candelaresi, Silvia Taffetani, Ursula Schindler, Giampiero Macarri, Kleemann Heinz-Werner, Luciano Trozzi, Emanuele Bendia
Publikováno v:
Hepatology. 37:256-266
The aim of this study was to evaluate the effect of cariporide, a selective Na(+)/H(+) exchange inhibitor, on isolated and cultured hepatic stellate cells (HSCs) and in 2 in vivo models of rat liver fibrosis. Platelet-derived growth factor (PDGF)-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e7e569f2914febaf9dc75329081685
https://doi.org/10.1053/jhep.2003.50028
https://doi.org/10.1053/jhep.2003.50028
Autor:
Gianluca Svegliati Baroni, Luciano Trozzi, Emanuele Bendia, Stefania Saccomanno, F. Ridolfi, Silvia Taffetani, Paola Sterpetti, Alessandro Casini, Antonio Benedetti, Marco Marzioni, Elisabetta Ceni, Antonio Di Sario
Publikováno v:
Journal of Hepatology. 37:584-591
Background/Aims : Pirfenidone has been recently shown to reduce dimethynitrosamine-induced liver fibrosis in the rat, but no information are available on the effect of this drug on cultured hepatic stellate cells (HSC). Methods : HSC proliferation wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f477b4b97304c9ca1539a92d89a06111
https://doi.org/10.1016/s0168-8278(02)00245-3
https://doi.org/10.1016/s0168-8278(02)00245-3
Autor:
Marco Marzioni, Laura Agostinelli, Stefania Saccomanno, Chiara Rychlicki, Gianluca Svegliati-Baroni, Samuele De Minicis, Cinzia Candelaresi, Luciano Trozzi, Silvia Taffetani, Antonio Benedetti
Publikováno v:
Liver International; Vol 32
Liver International
Liver International
BACKGROUND: Survival of hepatic stellate cells (HSCs) is a hallmark of liver fibrosis, while the induction of HSC apoptosis may induce recovery. Activated HSC are resistant to many pro-apoptotic stimuli. To this issue, the role of Endoplasmic Reticul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8377501d49e90f1c3dc64c2ff5a9296d
https://pubmed.ncbi.nlm.nih.gov/22938186
https://pubmed.ncbi.nlm.nih.gov/22938186