Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Silvia Sgambellone"'
Autor:
Silvia Sgambellone, Silvia Marri, Stefano Catarinicchia, Alessandro Pini, Dilip K. Tosh, Kenneth A. Jacobson, Emanuela Masini, Daniela Salvemini, Laura Lucarini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13300 (2022)
Adenosine receptors (ARs) are involved in the suppression and development of inflammatory and fibrotic conditions. Specifically, AR activation promotes differentiation of lung fibroblasts into myofibroblasts, typical of a fibrotic event. Pulmonary fi
Externí odkaz:
https://doaj.org/article/7b1650afed0040598dbd1acee7eb001e
Autor:
Mariaconcetta Durante, Silvia Sgambellone, Laura Lucarini, Paola Failli, Annunziatina Laurino, Debora Collotta, Gustavo Provensi, Emanuela Masini, Massimo Collino
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
It is known that fructose may contribute to myocardial vulnerability to ischemia/reperfusion (I/R) injury. D-tagatose is a fructose isomer with less caloric value and used as low-calorie sweetener. Here we compared the metabolic impact of fructose or
Externí odkaz:
https://doaj.org/article/041abf166ee64307b195e06e1b83498e
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 609 (2022)
The first properties of histamine (HA) that were elucidated were vasodilation and contraction of smooth muscles in the gut after stimulating gastric acid secretion and constriction of the bronchial area during anaphylaxis [...]
Externí odkaz:
https://doaj.org/article/64fcba5f8b33422187202b06d7ffc401
Autor:
Arianna Carolina Rosa, Patrizia Nardini, Silvia Sgambellone, Maura Gurrieri, Simona Federica Spampinato, Alfonso Dell’Accio, Paul L Chazot, Ilona Obara, Wai L Liu, Alessandro Pini
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 184 (2022)
Among the histamine receptors, growing evidence points to the histamine H3 receptor as a pharmacological candidate to counteract the autonomic neuropathy associated with diabetes. The study aimed to evaluate the effect of PF00868087 (also known as ZP
Externí odkaz:
https://doaj.org/article/e499ba4ea6514e01847df64e78640c43
Autor:
Laura Micheli, Mariaconcetta Durante, Elena Lucarini, Silvia Sgambellone, Laura Lucarini, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Emanuela Masini
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1447 (2021)
A3 adenosine receptor (A3AR) agonists have emerged as potent relievers of neuropathic pain by a T cell-mediated production of IL-10. The H4 histamine receptor (H4R), also implicated in pain modulation, is expressed on T cells playing a preeminent rol
Externí odkaz:
https://doaj.org/article/01853348a7bd46b088b5f52888789778
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1186 (2021)
Glaucoma is a multifactorial neuropathy characterized by increased intraocular pressure (IOP), and it is the second leading cause of blindness worldwide after cataracts. Glaucoma combines a group of optic neuropathies characterized by the progressive
Externí odkaz:
https://doaj.org/article/8454c617b512406ea86cb692a13cd2aa
Autor:
Silvia Sgambellone, Silvia Marri, Serafina Villano, Emanuela Masini, Gustavo Provensi, Elena Bastia, Corinna Galli, Stefania Brambilla, Francesco Impagnatiello, Laura Lucarini
NCX 470, a nitric oxide (NO)-donating bimatoprost, was shown to ameliorate ocular hemodynamics and retinal physiology in rabbits following endothelin-1 (ET-1)-induced ischemia/reperfusion. Here we used the same model to compare NCX 470 (0.1% bid) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c30f3accfbc09d27ede441bc89c672c
https://doi.org/10.20944/preprints202305.0309.v1
https://doi.org/10.20944/preprints202305.0309.v1
Autor:
Mariaconcetta Durante, Silvia Sgambellone, Cecilia Lanzi, Patrizia Nardini, Alessandro Pini, Flavio Moroni, Emanuela Masini, Laura Lucarini
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Pulmonary fibrosis is the most frequent form of interstitial lung disease. Effective therapies are not yet available; novel therapeutic approaches are needed for counteracting fibrosis. Poly(ADP-ribose) polymerases are enzymes, involved in DNA repair
Externí odkaz:
https://doaj.org/article/5c92be04260341febbbfc88a6cf766b6
Autor:
Laura Lucarini, Mariaconcetta Durante, Silvia Sgambellone, Cecilia Lanzi, Elisabetta Bigagli, Ozlem Akgul, Emanuela Masini, Claudiu T. Supuran, Fabrizio Carta
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1307 (2020)
Pulmonary fibrosis is a severe lung disease with progressive worsening of dyspnea, characterized by chronic inflammation and remodeling of lung parenchyma. Carbonic anhydrases are a family of zinc-metallo-enzymes that catalyze the reversible intercon
Externí odkaz:
https://doaj.org/article/f907a1aa74904e6ca44cc7ae3faeda42
Autor:
Silvia, Sgambellone, Silvia, Marri, Stefano, Catarinicchia, Alessandro, Pini, Dilip K, Tosh, Kenneth A, Jacobson, Emanuela, Masini, Daniela, Salvemini, Laura, Lucarini
Publikováno v:
International journal of molecular sciences. 23(21)
Adenosine receptors (ARs) are involved in the suppression and development of inflammatory and fibrotic conditions. Specifically, AR activation promotes differentiation of lung fibroblasts into myofibroblasts, typical of a fibrotic event. Pulmonary fi