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pro vyhledávání: '"Silvia Scarabelli"'
Autor:
Thomas Vorherr, Rudolf Griss, Kui-Thong Tan, Pier Luca D’Alessandro, Ruud Hovius, Kai Johnsson, Silvia Scarabelli
Publikováno v:
Journal of the American Chemical Society
We are introducing a new approach to evaluate cellular uptake of drugs and drug candidates into living cells. The approach is based on converting the protein target of a given class of compounds into a fluorescent biosensor. By measuring the binding
Autor:
Dominique Guianvarc'h, Mehdi Amoura, Albert Jeltsch, Thierry Drujon, Fabienne Burlina, Gérard Bolbach, Sandrine Sagan, Silvia Scarabelli, Karine Guitot
Publikováno v:
Analytical biochemistry. 456
Histone lysine methyltransferases (HKMTs) are enzymes that play an essential role in epigenetic regulation. Thus, identification of inhibitors specifically targeting these enzymes represents a challenge for the development of new antitumor therapeuti
Autor:
Silvia Scarabelli
Publikováno v:
Nature Nanotechnology.