Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Silvia Scali"'
Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging
Autor:
Jlenia Brunetti, Giulia Riolo, Mariangela Gentile, Andrea Bernini, Eugenio Paccagnini, Chiara Falciani, Luisa Lozzi, Silvia Scali, Lorenzo Depau, Alessandro Pini, Pietro Lupetti, Luisa Bracci
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Near-infrared quantum dots (NIR QDs) are a new class of fluorescent labels with excellent bioimaging features, such as high fluorescence intensity, good fluorescence stability, sufficient electron density, and strong tissue-penetr
Externí odkaz:
https://doaj.org/article/3fa4334a5d7749a19cd6a5b86c810471
Autor:
Jlenia Brunetti, Sara Piantini, Marco Fragai, Silvia Scali, Giulia Cipriani, Lorenzo Depau, Alessandro Pini, Chiara Falciani, Stefano Menichetti, Luisa Bracci
Publikováno v:
Molecules, Vol 25, Iss 5, p 1088 (2020)
The development of selective tumor targeting agents to deliver multiple units of chemotherapy drugs to cancer tissue would improve treatment efficacy and greatly advance progress in cancer therapy. Here we report a new drug delivery system based on a
Externí odkaz:
https://doaj.org/article/2f1af35762f44faa918f0ad83bd8a64a
Autor:
Luisa Bracci, Elisabetta Mandarini, Jlenia Brunetti, Lorenzo Depau, Alessandro Pini, Lucia Terzuoli, Silvia Scali, Chiara Falciani
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194744 (2018)
Heparan sulfate proteoglycans, HSPGs, modulate major transformations of cancer cells, leading to tumor growth, invasion and metastasis. HSPGs also regulate neo-angiogenesis which prompts cancer progression and metastatic spread. A different aspect of
Externí odkaz:
https://doaj.org/article/203a3915bc814d93a0c8f1ca2b783b06
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 7255-7268 (2014)
We report the identification of a new human tumor necrosis factor-alpha (TNF-α) specific peptide selected by competitive panning of a phage library. Competitive elution of phages was obtained using the monoclonal antibody adalimumab, which neutraliz
Externí odkaz:
https://doaj.org/article/6b80eba1e5114768a58c2f2e07ed28c5
Autor:
Chiara Falciani, Luisa Lozzi, Simona Pollini, Vincenzo Luca, Veronica Carnicelli, Jlenia Brunetti, Barbara Lelli, Stefano Bindi, Silvia Scali, Antonio Di Giulio, Gian Maria Rossolini, Maria Luisa Mangoni, Luisa Bracci, Alessandro Pini
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46259 (2012)
The branched M33 antimicrobial peptide was previously shown to be very active against Gram-negative bacterial pathogens, including multidrug-resistant strains. In an attempt to produce back-up molecules, we synthesized an M33 peptide isomer consistin
Externí odkaz:
https://doaj.org/article/6fa108c5020d4f499fc5bcf653798a8e
Autor:
Anna Provvidenza Privitera, Silvia Scalisi, Greta Paternò, Elena Cerutti, Morgana D’Amico, Pier Giuseppe Pelicci, Mario Faretta, Gaetano Ivan Dellino, Alberto Diaspro, Luca Lanzanò
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract To understand how oncogenes affect genome organization, it is essential to visualize fundamental processes such as DNA replication and transcription at high resolution in intact cells. At the same time, it is important to determine the progr
Externí odkaz:
https://doaj.org/article/0426e5ba68e34909b7ca1e6d34d45513
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Performing accurate Fluorescence Correlation Spectroscopy (FCS) measurements in cells can be challenging due to cellular motion or other intracellular processes. In this respect, it has recently been shown that analysis of FCS data in short
Externí odkaz:
https://doaj.org/article/67b66e32ea45407885be97543524cfab
Autor:
Elisabetta D'Aversa, Gian Maria Rossolini, Simona Pollini, Leila Quercini, Stefano Bindi, Giulia Riolo, Silvia Scali, Chiara Falciani, Luisa Bracci, Pietro Lupetti, Alessandro Pini, Sabine Wronski, Mariangela Gentile, Ilaria Lampronti, Jlenia Brunetti
Publikováno v:
The FASEB Journal. 34:192-207
The peptide sequence KKIRVRLSA was synthesized in a dimeric structure (SET‐M33DIM) and evaluated as a candidate drug for infections due to multidrug‐resistant (MDR) Gram‐negative pathogens. SET‐M33DIM showed significant antibacterial activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305cd4ecc1490b1581ae8175d4c726cf
https://doi.org/10.1096/fj.201901896rr
https://doi.org/10.1096/fj.201901896rr
Autor:
Luisa Bracci, Chiara Falciani, Giulia Cipriani, Sara Piantini, Jlenia Brunetti, Lorenzo Depau, Stefano Menichetti, Alessandro Pini, Marco Fragai, Silvia Scali
Publikováno v:
Molecules, Vol 25, Iss 5, p 1088 (2020)
Molecules
Volume 25
Issue 5
Molecules
Volume 25
Issue 5
The development of selective tumor targeting agents to deliver multiple units of chemotherapy drugs to cancer tissue would improve treatment efficacy and greatly advance progress in cancer therapy. Here we report a new drug delivery system based on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1be038a6c09b6dcb7d820124db70fa5
https://www.mdpi.com/1420-3049/25/5/1088
https://www.mdpi.com/1420-3049/25/5/1088
Publikováno v:
Amino acids. 52(6-7)
The tumor-specific tetrabranched peptide NT4 binds membrane sulfate glycosaminoglycans and receptors belonging to the low density lipoprotein receptor-related protein (LRP) family, like LRP6, which are overexpressed in cancer. The binding occurs thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a01c6cf5e89ff2a6b983bc35eeeb9ca
https://pubmed.ncbi.nlm.nih.gov/32556741
https://pubmed.ncbi.nlm.nih.gov/32556741