Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Silvia Remeseiro"'
Autor:
Craig A. Vincent, Silvia Remeseiro
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 1849-1852 (2024)
A first‐in‐human trial demonstrated that a vaccine targeting the histone mutation H3K27M can induce an immune response, in a mutation‐specific manner, in patients with diffuse midline glioma. In a recent study by Boschert et al., the same group
Externí odkaz:
https://doaj.org/article/7eb562fca33d4a7cb5338788b4dafa4f
Autor:
Nils Dennhag, Abraha Kahsay, Itzel Nissen, Hanna Nord, Maria Chermenina, Jiao Liu, Anders Arner, Jing-Xia Liu, Ludvig J. Backman, Silvia Remeseiro, Jonas von Hofsten, Fatima Pedrosa Domellöf
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract In muscular dystrophies, muscle fibers loose integrity and die, causing significant suffering and premature death. Strikingly, the extraocular muscles (EOMs) are spared, functioning well despite the disease progression. Although EOMs have be
Externí odkaz:
https://doaj.org/article/25b786ad9b1041379d41d3d2479b5d0d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Several preclinical models have been recently developed for metabolic associated fatty liver disease (MAFLD) and associated hepatocellular carcinoma (HCC) but comprehensive analysis of the regulatory and transcriptional landscapes underlying
Externí odkaz:
https://doaj.org/article/b1a42a930e8d447d864dfaf0d5f476af
Autor:
Chaitali Chakraborty, Itzel Nissen, Craig A. Vincent, Anna-Carin Hägglund, Andreas Hörnblad, Silvia Remeseiro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Chromatin organization controls transcription by modulating 3D-interactions between enhancers and promoters in the nucleus. Alterations in epigenetic states and 3D-chromatin organization result in gene expression changes contributing to canc
Externí odkaz:
https://doaj.org/article/f0d7762f42134f91a46e8618b1255558
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Glioblastoma (GB) is the most aggressive of all primary brain tumours and due to its highly invasive nature, surgical resection is nearly impossible. Patients typically rely on radiotherapy with concurrent temozolomide (TMZ) treat
Externí odkaz:
https://doaj.org/article/9c5acf6e1a2e40de8f91c15037e33142
Autor:
Ana López-Pérez, Stefan Norlin, Pär Steneberg, Silvia Remeseiro, Helena Edlund, Andreas Hörnblad
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract AMP-activated protein kinase (AMPK) has an important role in cellular energy homeostasis and has emerged as a promising target for treatment of Type 2 Diabetes (T2D) due to its beneficial effects on insulin sensitivity and glucose homeostasi
Externí odkaz:
https://doaj.org/article/fb720488e1fb44268248dcc58487c00b
Autor:
Soran Dakhel, Wayne I. L. Davies, Justin V. Joseph, Tushar Tomar, Silvia Remeseiro, Lena Gunhaga
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background Organ culture models have been used over the past few decades to study development and disease. The in vitro three-dimensional (3D) culture system of organoids is well known, however, these 3D systems are both costly and difficult
Externí odkaz:
https://doaj.org/article/6701154820b9473684904a73538d635e
Autor:
Andreas Hörnblad, Silvia Remeseiro
Publikováno v:
Cells, Vol 11, Iss 9, p 1404 (2022)
Genome architecture, epigenetics and enhancer function control the fate and identity of cells. Reprogramming to induced pluripotent stem cells (iPSCs) changes the transcriptional profile and chromatin landscape of the starting somatic cell to that of
Externí odkaz:
https://doaj.org/article/ed83a28276c0483881346a65d68b64fb
Autor:
Andres J. Lopez-Contreras, Isabel Ruppen, Maria Nieto-Soler, Matilde Murga, Sara Rodriguez-Acebes, Silvia Remeseiro, Sara Rodrigo-Perez, Ana M. Rojas, Juan Mendez, Javier Muñoz, Oscar Fernandez-Capetillo
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1105-1116 (2013)
DNA replication is facilitated by multiple factors that concentrate in the vicinity of replication forks. Here, we developed an approach that combines the isolation of proteins on nascent DNA chains with mass spectrometry (iPOND-MS), allowing a compr
Externí odkaz:
https://doaj.org/article/a109e633654249909b199aa063cf4c58
Glioblastoma (GB) is the most aggressive of all primary brain tumours. Patients typically rely on radiotherapy with concurrent temozolomide (TMZ) treatment and face a median survival of ∼14 months. Alterations in the Epidermal Growth Factor Recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6beff2f07d882de83c7fd0632242b538
https://doi.org/10.1101/2023.02.22.529507
https://doi.org/10.1101/2023.02.22.529507