Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Silvia Ponzoni"'
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 53, Iss 3b, Pp 711-717 (1995)
O emprego de modelos experimentais de parkinsonismo tem contribuído não só para explicar o conhecimento das funções dos gânglios basais como também tem permitido o surgimento de várias hipóteses para explicar os processos neurodegeneratives
Externí odkaz:
https://doaj.org/article/96fa9be6a3254325b548d8c58fbab67e
Autor:
Silvia Ponzoni
Publikováno v:
Invertebrate neuroscience : IN. 17(2)
Manganese (Mn) is an essential metal for the development and function of the mammalian brain; however, excess Mn accumulation may cause neurological abnormalities resembling Parkinson’s disease due to reductions in brain dopamine levels. Because do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dfead2fb354331e2259c7d069aa609
https://pubmed.ncbi.nlm.nih.gov/28451884
https://pubmed.ncbi.nlm.nih.gov/28451884
Autor:
Isabel Cristina Vicente de Rezende, Artur Fernandes, Silvia Ponzoni, Eduardo Fontana de Oliveira
Publikováno v:
Brain Research. 1317:277-285
Unilateral microinjection of manganese into the rat substantia nigra pars compacta (SNpc) leads to the death of nigral neurons and a decrease in dopamine (DA) within the ipsilateral striatum. l -deprenyl, an irreversible inhibitor of monoamine oxidas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aae40703fc6f9e84025c8f314381b042
https://doi.org/10.1016/j.brainres.2009.12.066
https://doi.org/10.1016/j.brainres.2009.12.066
Autor:
Wagner José Barreto, Eduardo Di Mauro, Yoshio Kawano, Sônia Regina Giancoli Barreto, Herica Aparecida Magosso, Silvia Ponzoni, Waleria P. Silva
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 136:701-712
Dopamine oxidation by iron oxide (Fe2O3) was studied in the presence and absence of sodium thiosulfate in aqueous medium around pH 7 by UV-Vis spectroscopy. The pH changes from 6 to 8 indicate that the dopamine oxidation process has occurred producin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a25de1781e9daaadb3b0f82af23626ab
https://doi.org/10.1007/s00706-004-0273-8
https://doi.org/10.1007/s00706-004-0273-8
Publikováno v:
Neuroscience Letters. 328:170-174
Chronic exposure to manganese (Mn) positively correlates with the occurrence of Parkinsonism but little is known about mechanisms of its neurotoxicity. In the present study, we determined the clearance of Mn from rat substantia nigra after its nigral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d7f4d75684c6583d68993d2c7d41e4
https://doi.org/10.1016/s0304-3940(02)00464-0
https://doi.org/10.1016/s0304-3940(02)00464-0
Autor:
Silvia Ponzoni
Publikováno v:
Tissuecell. 46(6)
Given the importance of catecholamines in coordinating physiological and behavioral responses in brachyurans, the present study was designed to investigate the distribution of tyrosine hydroxylase (TH)-positive cells and fibers in the ventral nerve c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7d86289edd65018901253b9428f40d
https://pubmed.ncbi.nlm.nih.gov/25217291
https://pubmed.ncbi.nlm.nih.gov/25217291
Publikováno v:
Metal Ions in Life Sciences ISBN: 9789400755604
The present review addresses issues pertinent to Mn accumulation and its mechanisms of transport, its neurotoxicity and mechanisms of neurodegeneration. The role of mitochondria and glia in this process is emphasized. We also discuss gene x environme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28363517d9273e9593cc5ff27a535ac
https://doi.org/10.1007/978-94-007-5561-1_6
https://doi.org/10.1007/978-94-007-5561-1_6
Autor:
Silvia Ponzoni
Publikováno v:
Neuroscience letters. 506(1)
The present study was designed to address the role of macrophages in Mn-induced neurotoxicity and to test the hypothesis that minocycline, a tetracycline derivative, attenuates the biochemical and morphological sequelae of Mn. Mn was unilaterally mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46516327e6ce9a944c40e721d1d9d486
https://pubmed.ncbi.nlm.nih.gov/22085690
https://pubmed.ncbi.nlm.nih.gov/22085690
Autor:
Artur, Fernandes, Eduardo Fontana, de Oliveira, Isabel Cristina Vicente, de Rezende, Silvia, Ponzoni
Publikováno v:
Brain research. 1317
Unilateral microinjection of manganese into the rat substantia nigra pars compacta (SNpc) leads to the death of nigral neurons and a decrease in dopamine (DA) within the ipsilateral striatum. L-deprenyl, an irreversible inhibitor of monoamine oxidase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1aab600442c09683795152fda0fa2f2
https://pubmed.ncbi.nlm.nih.gov/20045397
https://pubmed.ncbi.nlm.nih.gov/20045397
Autor:
Silvia Ponzoni, Norberto Garcia-Cairasco, Francisco Silveira Guimarães, Elaine Aparecida Del Bel
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 24(2)
1. 1. Microinjection of manganese chloride (MnCl2) into the rat substantia nigra pars compacta (SNc) induces a neurodegenerative process manifested by apomorphine-induced rotational behavior. Manganese intoxication produces a parkinsonism-like phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145489844cb99d42b1460c84097a90ff
https://pubmed.ncbi.nlm.nih.gov/10800753
https://pubmed.ncbi.nlm.nih.gov/10800753