Výsledky vyhledávání - "Silvia Petrik"

A Feasibility Study of Cyclophosphamide, Trastuzumab, and an Allogeneic GM-CSF-secreting Breast Tumor Vaccine for HER-2+ Metastatic Breast Cancer

Granulocyte-macrophage colony-stimulating factor (GM-CSF)–secreting tumor vaccines are bioactive, but limited by disease burden and immune tolerance. Cyclophosphamide augments vaccine activity in tolerant neu mice and in patients with metastatic br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74843e9b7ff25d1e0a040fe740a6b481
https://europepmc.org/articles/PMC4211036/

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Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation

Autor: Leisha A. Emens, Steven Piantadosi, Elizabeth M. Jaffee, Justin M. Asquith, Marina Laiko, Vered Stearns, Barbara A. Biedrzycki, Barry Kobrin, Silvia Petrik, John H. Fetting, Antonio C. Wolff, James M. Leatherman, Nancy E. Davidson, Mary L. Disis, Maithili M. Daphtary, Xiaobu Ye, Joy Levi

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 27, iss 35

Purpose Granulocyte-macrophage colony-stimulating factor (GM-CSF) –secreting tumor vaccines have demonstrated bioactivity but may be limited by disease burdens and immune tolerance. We tested the hypothesis that cyclophosphamide (CY) and doxorubici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066f88f45082c54f5efaae5105561f24
https://pubmed.ncbi.nlm.nih.gov/19805669

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A feasibility study of combination therapy with trastuzumab (T), cyclophosphamide (CY), and an allogeneic GM-CSF-secreting breast tumor vaccine for the treatment of HER2+ metastatic breast cancer

Autor: Elizabeth Garrett-Mayer, Justin M. Asquith, Elizabeth M. Jaffee, J. Levi, Vered Stearns, James M. Leatherman, Marina Laiko, R. Gupta, Nancy E. Davidson, Leisha A. Emens, Tianna Dauses, Antonio C. Wolff, Maithili M. Daphtary, Barry Kobrin, Silvia Petrik, S. Atay-Rosenthal, Xiaobu Ye

Publikováno v: Journal of Clinical Oncology. 29:2535-2535

2535 Background: Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting tumor vaccines are bioactive, but limited by disease burdens and immune tolerance. Cyclophosphamide (CY) augment...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af7d6fe1ef954968ad5b2777ea62cbbf
https://doi.org/10.1200/jco.2011.29.15_suppl.2535

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Increasing doses of cyclophosphamide suppress antigen-specific T helper-dependent immunity induced by a GM-CSF-secreting breast tumor vaccine

Autor: Justin M. Asquith, Maithili M. Daphtary, Nancy E. Davidson, Mary L. Disis, James M. Leatherman, S Piantadosi, Silvia Petrik, Leisha A. Emens, John H. Fetting, Elizabeth M. Jaffee

Publikováno v: Journal of Clinical Oncology. 26:3009-3009

3009 Background: Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting tumor vaccines have shown promise, but their activity is limited by immune tolerance. We tested the hypothesis that integrating vaccination with cyclophosphamide (CY

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b393a6ac63250fd118a28a44f0250d69
https://doi.org/10.1200/jco.2008.26.15_suppl.3009

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