Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Silvia Perez-Yanes"'
Autor:
Agustín Valenzuela-Fernández, Romina Cabrera-Rodriguez, Laura Ciuffreda, Silvia Perez-Yanes, Judith Estevez-Herrera, Rafaela González-Montelongo, Julia Alcoba-Florez, Rodrigo Trujillo-González, Diego García-Martínez de Artola, Helena Gil-Campesino, Oscar Díez-Gil, José M. Lorenzo-Salazar, Carlos Flores, Jonay Garcia-Luis
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory system and several organs and tissues, and may lead to death, have shown how scie
Externí odkaz:
https://doaj.org/article/4495ef48f9ae48a1a31e5006c60b4e4d
Autor:
Silvia Pérez-Yanes, Iria Lorenzo-Sánchez, Romina Cabrera-Rodríguez, Jonay García-Luis, Rodrigo Trujillo-González, Judith Estévez-Herrera, Agustín Valenzuela-Fernández
Publikováno v:
Cells, Vol 13, Iss 7, p 598 (2024)
Zika virus (ZIKV) infection and pathogenesis are linked to the disruption of neurogenesis, congenital Zika syndrome and microcephaly by affecting neural progenitor cells. Nonstructural protein 5 (NS5) is the largest product encoded by ZIKV-RNA and is
Externí odkaz:
https://doaj.org/article/c122ba960d6a4667b363c152bf5f07af
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Iria Lorenzo-Sánchez, Rodrigo Trujillo-González, Judith Estévez-Herrera, Jonay García-Luis, Agustín Valenzuela-Fernández
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13104 (2023)
HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (i.e., actin and intermediate filaments (AFs and IFs) and microtubules (MTs)) to achieve the viral cycle. HIV-1 modifies cytoskeletal organization and dynamics by acting
Externí odkaz:
https://doaj.org/article/e77ea9eab71b4df6a6c67d39173ac432
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Iria Lorenzo-Sánchez, Judith Estévez-Herrera, Jonay García-Luis, Rodrigo Trujillo-González, Agustín Valenzuela-Fernández
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7658 (2023)
The transactive response DNA-binding protein (TARDBP/TDP-43) is known to stabilize the anti-HIV-1 factor, histone deacetylase 6 (HDAC6). TDP-43 has been reported to determine cell permissivity to HIV-1 fusion and infection acting on tubulin-deacetyla
Externí odkaz:
https://doaj.org/article/508c4cb1a9604a4a9e17383879c59bf1
Autor:
Silvia Pérez-Yanes, María Pernas, Silvia Marfil, Romina Cabrera-Rodríguez, Raquel Ortiz, Víctor Urrea, Carla Rovirosa, Judith Estévez-Herrera, Isabel Olivares, Concepción Casado, Cecilio Lopez-Galindez, Julià Blanco, Agustín Valenzuela-Fernández
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The understanding of HIV-1 pathogenesis and clinical progression is incomplete due to the variable contribution of host, immune, and viral factors. The involvement of viral factors has been investigated in extreme clinical phenotypes from rapid progr
Externí odkaz:
https://doaj.org/article/5e4739c8580d48f4a215263e47f633ee
Autor:
Agustín Valenzuela-Fernández, Romina Cabrera-Rodríguez, Concha Casado, Silvia Pérez-Yanes, María Pernas, Jonay García-Luis, Silvia Marfil, Isabel Olivares, Judith Estévez-Herrera, Rodrigo Trujillo-González, Julià Blanco, Cecilio Lopez-Galindez
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2172 (2022)
In the absence of antiviral therapy, HIV-1 infection progresses to a wide spectrum of clinical manifestations that are the result of an entangled contribution of host, immune and viral factors. The contribution of these factors is not completely esta
Externí odkaz:
https://doaj.org/article/6a1c4b76e28a4bbd8416d44bc7ae05e9
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Judith Estévez-Herrera, Daniel Márquez-Arce, Cecilia Cabrera, Lucile Espert, Julià Blanco, Agustín Valenzuela-Fernández
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
HIV/AIDS is still a global threat despite the notable efforts made by the scientific and health communities to understand viral infection, to design new drugs or to improve existing ones, as well as to develop advanced therapies and vaccine designs f
Externí odkaz:
https://doaj.org/article/05cd32a89c824ee198a38a1e6452d653
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Rafaela Montelongo, José M. Lorenzo-Salazar, Judith Estévez-Herrera, Jonay García-Luis, Antonio Íñigo-Campos, Luis A. Rubio-Rodríguez, Adrián Muñoz-Barrera, Rodrigo Trujillo-González, Roberto Dorta-Guerra, Concha Casado, María Pernas, Julià Blanco, Carlos Flores, Agustín Valenzuela-Fernández
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6180 (2022)
The transactive response DNA-binding protein (TARDBP/TDP-43) influences the processing of diverse transcripts, including that of histone deacetylase 6 (HDAC6). Here, we assessed TDP-43 activity in terms of regulating CD4+ T-cell permissivity to HIV-1
Externí odkaz:
https://doaj.org/article/e20d8b360a12475eb7083b4735895af0
Autor:
Sara Marrero-Hernández, Daniel Márquez-Arce, Romina Cabrera-Rodríguez, Judith Estévez-Herrera, Silvia Pérez-Yanes, Jonathan Barroso-González, Ricardo Madrid, José-David Machado, Julià Blanco, Agustín Valenzuela-Fernández
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
HIV Nef is a central auxiliary protein in HIV infection and pathogenesis. Our results indicate that HDAC6 promotes the aggresome/autophagic degradation of the viral polyprotein Pr55Gag to inhibit HIV-1 production. Nef counteracts this antiviral activ
Externí odkaz:
https://doaj.org/article/29d60b530a264db38f12f86bb3308796
Autor:
Judith Estévez-Herrera, Silvia Pérez-Yanes, Romina Cabrera-Rodríguez, Daniel Márquez-Arce, Rodrigo Trujillo-González, José-David Machado, Ricardo Madrid, Agustín Valenzuela-Fernández
Publikováno v:
Vaccines, Vol 9, Iss 3, p 294 (2021)
Zika virus (ZIKV) infection and its associated congenital and other neurological disorders, particularly microcephaly and other fetal developmental abnormalities, constitute a World Health Organization (WHO) Zika Virus Research Agenda within the WHO
Externí odkaz:
https://doaj.org/article/92a270ec2f8c48bb9b548c082d669171