Výsledky vyhledávání - "Silvia Pellerito"

Photoexposition discriminates Notch 1 expression in human cutaneous squamous cell carcinoma

Autor: Claudia Di Serio, Francesca Tarantini, John Panelos, Daniela Massi, Silvia Pellerito, Milena Paglierani, Nicola Pimpinelli, Vincenza Maio, Marco Santucci

Publikováno v: Modern Pathology. 21:316-325

The Notch signaling pathway may play opposing roles in cancer. It can be oncosuppressive or protumoral, depending on the cellular and tissue context. In skin cancer, Notch 1 expression is downregulated, thus supporting the hypothesis of an oncosuppre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05a15d8253eedf49ace4bcf9ddb54d4
https://doi.org/10.1038/modpathol.3801007

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Kynurenic Acid Inhibits the Release of the Neurotrophic Fibroblast Growth Factor (FGF)-1 and Enhances Proliferation of Glia Cells, in vitro

Autor: Silvia Pellerito, Claudia Di Serio, Patrizia Mirone, Isabella Micucci, Giulio Masotti, Flavio Moroni, Francesca Tarantini, Laura Doria, Ilaria Angeli, Andrea Cozzi

Publikováno v: Cellular and Molecular Neurobiology. 25:981-993

1. Kynurenic (KYNA) and quinolinic (QUIN) acids are neuroactive tryptophan metabolites formed along the kynurenine pathway: the first is considered a non-competitive antagonist and the second an agonist of glutamate receptors of NMDA type. The affini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52094cc55c4c72b7a9be91facb7eac7f
https://doi.org/10.1007/s10571-005-8469-y

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Resistin level in coronary artery disease and heart failure: the central role of kidney function

Autor: Alice Foschini, Claudia Di Serio, Matteo Monami, Francesca Tarantini, Silvia Pellerito, Niccolò Marchionni, Enrico Mossello, Stefano Fumagalli, Samuele Baldasseroni, Nadia Bartoli, Paolo Valoti, Francesco Orso, Gian Franco Gensini, Edoardo Mannucci, Claudia Colombi

Publikováno v: Journal of cardiovascular medicine (Hagerstown, Md.). 14(2)

The aim of this study was to evaluate resistin levels in patients with coronary artery disease (CAD) with or without chronic heart failure, in order to define its independent predictor.One hundred and seven outpatients with CAD were enrolled in the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1602a25b54b73e7bd37997fbc8af10f
https://pubmed.ncbi.nlm.nih.gov/22240747

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Multiple shocks affect thoracic electrical impedance during external cardioversion of atrial fibrillation

Autor: Luigi Padeletti, Francesca Tarantini, Margherita Padeletti, Paolo Valoti, Stefano Fumagalli, Niccolò Marchionni, Lorenzo Boncinelli, Claudia Di Serio, Francesca Caldi, Yasmine Makhanian, S. Serge Barold, Silvia Pellerito

Publikováno v: Pacing and clinical electrophysiology : PACE. 32(3)

Background: Thoracic impedance (TI) influences the success of external cardioversion (ECV) or defibrillation because current intensity traversing the heart is inversely related to TI. Experimental data suggest that TI decreases after multiple shocks.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fe3efa80bb173829520615cb630536
https://pubmed.ncbi.nlm.nih.gov/19272068

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The release of fibroblast growth factor-1 from melanoma cells requires copper ions and is mediated by phosphatidylinositol 3-kinase/Akt intracellular signaling pathway

Autor: Francesca Tarantini, Claudia Di Serio, Giulio Masotti, Silvia Pellerito, Igor Prudovsky, Niccolò Marchionni, Isabella Micucci, Matteo Landriscina, Laura Doria, Daniela Massi

Publikováno v: Cancer letters. 267(1)

Melanoma is a highly invasive tumor with elevated mortality rates. Progression and aggressiveness appear related to the achievement of an angiogenic phenotype. Melanoma cells express several angiogenic factors, including fibroblast growth factor (FGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba1cf550124c8bba45347ef757cf5a4
https://pubmed.ncbi.nlm.nih.gov/18400376

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Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism

Autor: Silvia Pellerito, Maria F. Duarte, Giuseppe Cirino, Claudia Di Serio, Francesca Tarantini, Giulio Masotti, Marco Santucci, Niccolò Marchionni, Igor Prudovsky, Antonella Naldini, Pierangelo Geppetti, Daniela Massi

Publikováno v: Basicclinical pharmacologytoxicology. 101(1)

Thrombin, a key mediator of blood coagulation, exerts a large number of cellular actions via activation of a specific G-protein-coupled receptor, named protease-activated receptor 1 (PAR1). Several studies in experimental animals have demonstrated a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f4df3b5da6b1aca0081d258162e535
https://pubmed.ncbi.nlm.nih.gov/17577318

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Analysis of protease-activated receptor-1 and -2 in human scar formation

Autor: Silvia Pellerito, Milena Paglierani, Giuseppe Cirino, Fabio Carraro, Serena Materazzi, C. Di Serio, Marco Santucci, Pierangelo Geppetti, C Ardinghi, Antonella Naldini, Daniela Massi, Francesca Tarantini

Protease-activated receptor (PAR)-1 and PAR-2 are reported to contribute to the fibrotic process in a number of organs, including lung, liver, pancreas, and kidney. The aim of this study was to localize expression and biological activity of PAR-1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72e612a9ccbad4607c7b978aa288061
http://hdl.handle.net/11588/333610

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Evidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma

Autor: Marco Santucci, Francesca Tarantini, Claudia Di Serio, Alessandro Franchi, Pierangelo Geppetti, Giuseppe Cirino, Milena Paglierani, Giuseppe Leoncini, Daniela Massi, Silvia Pellerito

The Notch signaling has been implicated in the regulation of self-renewal of adult stem cells and differentiation of precursors along a specific cell lineage, in normal embryonic development and organogenesis. There is also evidence that signaling th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbef140713fb13d22e633688828eab7
http://hdl.handle.net/11568/1014342

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Comments on 'Blockade of Angiogenesis by Small Molecule Antagonists to Protease-Activated Receptor-1: Association with Endothelial Cell Growth Suppression and Induction of Apoptosis'

Autor: Francesca Tarantini, Silvia Pellerito, C. Di Serio

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 324:404-405

This letter is in response to the report by Zania et al. ([2006][1]). The authors used in vitro (Matrigel) and in vivo (chick chorioallantoic membrane) models of angiogenesis to demonstrate that small molecule PAR1 antagonists, SCH79797 and RWJ56110,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a92c9857047cacbb5df2bf344e8b7c37
https://doi.org/10.1124/jpet.107.131847

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