Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Silvia Oggero"'
Autor:
George Sideris-Lampretsas, Silvia Oggero, Lynda Zeboudj, Rita Silva, Archana Bajpai, Gopuraja Dharmalingam, David A. Collier, Marzia Malcangio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Musculoskeletal chronic pain is prevalent in individuals with Alzheimer’s disease (AD); however, it remains largely untreated in these patients, raising the possibility that pain mechanisms are perturbed. Here, we utilise the TASTPM transg
Externí odkaz:
https://doaj.org/article/62301ae215b043c49a0763e37f77b14f
Autor:
Jianmin Chen, Silvia Oggero, Chiara Cecconello, Jesmond Dalli, Hedayatullah Hayat, Ahmad Hjiej Andaloussi, Samra Sanni, Thomas EN Jonassen, Mauro Perretti
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 107005- (2023)
Aims: The cardio-protective and immuno-regulatory properties of RTP-026, a synthetic peptide that spans the Annexin-A1 (AnxA1) N-terminal region, were tested in rat acute myocardial infarction. Methods and results: In vitro, selective activation of f
Externí odkaz:
https://doaj.org/article/24ec03362e644c72af881404e8bf20c2
Autor:
Silvia Oggero, Monica deGaetano, Simone Marcone, Stephen Fitzsimons, Andreia L. Pinto, Dinara Ikramova, Mary Barry, David Burke, Trinidad Montero‐Melendez, Dianne Cooper, Thomas Burgoyne, Orina Belton, Lucy V. Norling, Eoin P. Brennan, Catherine Godson, Mauro Perretti
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Extracellular vesicles (EVs) are emerging as key players in different stages of atherosclerosis. Here we provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF‐α display pro‐inflammatory act
Externí odkaz:
https://doaj.org/article/e2e22bed7e5c4e41a80f8c691c19795d
Autor:
Stephen Fitzsimons, Silvia Oggero, Robyn Bruen, Cathal McCarthy, Moritz J. Strowitzki, Niall G. Mahon, Nicola Ryan, Eoin P. Brennan, Mary Barry, Mauro Perretti, Orina Belton
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundAtherosclerosis is a chronic inflammatory disease driven by macrophage accumulation in medium and large sized arteries. Macrophage polarization and inflammation are governed by microRNAs (miR) that regulate the expression of inflammatory pr
Externí odkaz:
https://doaj.org/article/4101455786014817856d757bad33233b
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Extracellular vesicles are a heterogeneous family of vesicles, generated from different subcellular compartments and released into the extracellular space. Composed of a lipid bilayer encompassing both soluble cytosolic material and nuclear component
Externí odkaz:
https://doaj.org/article/5c0bf3b51ff54e578d4a8721ab5d2d11
Autor:
Daniëlle M. Coenen, Alexandra C. A. Heinzmann, Silvia Oggero, Hugo J. Albers, Magdolna Nagy, Perrine Hagué, Marijke J. E. Kuijpers, Jean-Marie Vanderwinden, Andries D. van der Meer, Mauro Perretti, Rory R. Koenen, Judith M. E. M. Cosemans
Publikováno v:
Cells, Vol 10, Iss 8, p 1998 (2021)
Objective: platelets possess not only haemostatic but also inflammatory properties, which combined are thought to play a detrimental role in thromboinflammatory diseases such as acute coronary syndromes and stroke. Phosphodiesterase (PDE) 3 and -5 in
Externí odkaz:
https://doaj.org/article/dfaa86fe9ac8499a8d3fa4fa585321c1
Autor:
Silvia Oggero, Thomas Godec, Rick van Gorp, Adreia L. Pinto, Leon J. Schurgers, Chris Reutelingsperger, Peter Sever, Lucy V. Norling, Mauro Perretti, Ajay Gupta
Publikováno v:
Journal of Hypertension, 40(8), 1522-1529. LIPPINCOTT WILLIAMS & WILKINS
Background: Rapid and accurate new biomarkers to predict risk of cardiovascular disease (CVD) are essential. The utility of extracellular vesicles in predicting the CVD risk is postulated, yet it remains unknown whether their expression is altered in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9f7ef55f068420840747f42dddd238
https://doi.org/10.1097/hjh.0000000000003178
https://doi.org/10.1097/hjh.0000000000003178
Autor:
Silvia Oggero, Chiara Cecconello, Rita Silva, Lynda Zeboudj, George Sideris-Lampretsas, Mauro Perretti, Marzia Malcangio
Publikováno v:
Brain, Behavior, and Immunity
Pain is a persistent symptom of Rheumatoid Arthritis, and the K/BxN serum transfer model recapitulates both association and dissociation between pain and joint inflammation in RA. Furthermore, this model features monocyte/macrophage infiltration in j
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfd0a7e7f3e4c68fcacf5891255da79
https://pubmed.ncbi.nlm.nih.gov/36115544
https://pubmed.ncbi.nlm.nih.gov/36115544
Autor:
Hugo J. Albers, Magdolna Nagy, Perrine Hague, Rory R. Koenen, Silvia Oggero, Mauro Perretti, Jean-Marie Vanderwinden, Daniëlle M. Coenen, Alexandra C.A. Heinzmann, Andries D. van der Meer, Marijke J.E. Kuijpers, Judith M.E.M. Cosemans
Publikováno v:
Cells
Cells, Vol 10, Iss 1998, p 1998 (2021)
Cells, 10(8):1998. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 10
Issue 8
Cells, Vol 10, Iss 1998, p 1998 (2021)
Cells, 10(8):1998. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 10
Issue 8
Objective: platelets possess not only haemostatic but also inflammatory properties, which combined are thought to play a detrimental role in thromboinflammatory diseases such as acute coronary syndromes and stroke. Phosphodiesterase (PDE) 3 and -5 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838f724491a67ff9b481beb5f65dd733
https://pubmed.ncbi.nlm.nih.gov/34440764
https://pubmed.ncbi.nlm.nih.gov/34440764
Publikováno v:
Free radical biologymedicine. 175
Extracellular vesicles are small membrane-derived packages of information that are released from virtually all cell types. These nano-packages contain regulatory material including proteins, lipids, mRNA and microRNA and are a key mechanism of parace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd023df277fe0605ffe132c85f6ceea4
https://pubmed.ncbi.nlm.nih.gov/34461260
https://pubmed.ncbi.nlm.nih.gov/34461260